Determination of the proton LET using thin film solar cells coated with scintillating powder

Jeong, Seonghoon; Kim, Chan-Kyu; An, Seohyeon; Kwon, Yong‐Cheol; Pak, Sang‐il; Cheon, Wonjoong; Shin, Dongho; Lim, Young Kyung; Jeong, Jee–Heon; Kim, Hak‐Soo; Lee, Se Byeong

doi:10.1002/mp.15977

Cited by 2 publications

(1 citation statement)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Because the stopping power can be replaced by LET in the therapeutic proton beam, the LET can be calculated using Equations ( 3) and ( 4). It is given by the following equation [13]:…”

Section: Concept Of Let Measurementmentioning

confidence: 99%

Measurement of Proton Beam Dose-Averaged Linear Energy Transfer Using a Radiochromic Film

Pak

Jeong

et al. 2022

Progress in Medical Physics

View full text Add to dashboard Cite

Proton therapy has different relative biological effectiveness (RBE) compared with X-ray treatment, which is the standard in radiation therapy, and the fixed RBE value of 1.1 is widely used. However, RBE depends on a charged particle's linear energy transfer (LET); therefore, measuring LET is important. We have developed a LET measurement method using the inefficiency characteristic of an EBT3 film on a proton beam's Bragg peak (BP) region.Methods: A Gafchromic EBT3 film was used to measure the proton beam LET. It measured the dose at a 10-cm pristine BP proton beam in water to determine the quenching factor of the EBT3 film as a reference beam condition. Monte Carlo (MC) calculations of dose-averaged LET (LET d ) were used to determine the quenching factor and validation. The dose-averaged LETs at the 12-, 16-, and 20-cm pristine BP proton beam in water were calculated with the quenching factor.Results: Using the passive scattering proton beam nozzle of the National Cancer Center in Korea, the LET d was measured for each beam range. The quenching factor was determined to be 26.15 with 0.3% uncertainty under the reference beam condition. The dose-averaged LETs were measured for each test beam condition. Conclusions:We developed a method for measuring the proton beam LET using an EBT3 film.This study showed that the magnitude of the quenching effect can be estimated using only one beam range, and the quenching factor determined under the reference condition can be applied to any therapeutic proton beam range.

show abstract

“…Because the stopping power can be replaced by LET in the therapeutic proton beam, the LET can be calculated using Equations ( 3) and ( 4). It is given by the following equation [13]:…”

Section: Concept Of Let Measurementmentioning

confidence: 99%

Measurement of Proton Beam Dose-Averaged Linear Energy Transfer Using a Radiochromic Film

Pak

Jeong

et al. 2022

Progress in Medical Physics

View full text Add to dashboard Cite

show abstract

Feasibility study for the development of multilayered solar cells for proton linear energy transfer depth profile measurement

Jeong,

Kim,

Kim

et al. 2024

Medical Physics

View full text Add to dashboard Cite

BackgroundPrevious study proposed a method to measure linear energy transfer (LET) at specific points using the quenching magnitude of thin film solar cells. This study was conducted to propose a more advanced method for measuring the LET distribution.PurposeThis study focuses on evaluating the feasibility of estimating the proton LET distribution in proton therapy. The feasibility of measuring the proton LET and dose distribution simultaneously using a single‐channel configuration comprising two solar cells with distinct quenching constants is investigated with the objective of paving the way for enhanced proton therapy dosimetry.MethodsTwo solar cells with different quenching constants were used to estimate the proton LET distribution. Detector characteristics (e.g., dose linearity and dose‐rate dependency) of the solar cells were evaluated to assess their suitability for dosimetry applications. First, using a reference beam condition, the quenching constants of the two solar cells were determined according to the modified Birks equation. The signal ratios of the two solar cells were then evaluated according to proton LET in relation to the estimated quenching constants. The proton LET distributions of six test beams were obtained by measuring the signal ratios of the two solar cells at each depth, and the ratios were evaluated by comparing them with those calculated by Monte Carlo simulation.ResultsThe detector characterization of the two solar cells including dose linearity and dose‐rate dependence affirmed their suitability for use in dosimetry applications. The maximum difference between the LET measured using the two solar cells and that calculated by Monte Carlo simulation was 2.34 keV/µm. In the case of the dose distribution measured using the method proposed in this study, the maximum difference between range measured using the proposed method and that measured using a multilayered ionization chamber was 0.7 mm. The expected accuracy of simultaneous LET and dose distribution measurement using the method proposed in this study were estimated to be 3.82%. The signal ratios of the two solar cells, which are related to quenching constants, demonstrated the feasibility of measuring LET and dose distribution simultaneously.ConclusionThe feasibility of measuring proton LET and dose distribution simultaneously using two solar cells with different quenching constants was demonstrated. Although the method proposed in this study was evaluated using a single channel by varying the measuring depth, the results suggest that the proton LET and dose distribution can be simultaneously measured if the detector is configured in a multichannel form. We believe that the results presented in this study provide the envisioned transition to a multichannel configuration, with the promise of substantially advancing proton therapy's accuracy and efficacy in cancer treatment.

show abstract

Determination of the proton LET using thin film solar cells coated with scintillating powder

Cited by 2 publications

References 38 publications

Measurement of Proton Beam Dose-Averaged Linear Energy Transfer Using a Radiochromic Film

Measurement of Proton Beam Dose-Averaged Linear Energy Transfer Using a Radiochromic Film

Feasibility study for the development of multilayered solar cells for proton linear energy transfer depth profile measurement

Contact Info

Product

Resources

About