Determination of the Deuterium Content of a Sample of Deuterium Oxide by Three Methods.

Goldblatt, Maxwell; Jones, W.H.

doi:10.1021/ac60208a060

Cited by 15 publications

(3 citation statements)

References 3 publications

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“…The chemical and physical similarities of D 2 O to regular water make it difficult to quantify it in the D 2 O–H 2 O mixture. The prevailing methods for the quantitative determination of D 2 O, namely, gas chromatography–mass spectrometry, , nuclear magnetic spin resonance spectroscopy, , and Fourier transformed infrared spectroscopy, − have several drawbacks, such as nonportable setup, need of expensive instrumental design and specialized operators, time-consuming analysis, and complicated operations, leading to inconvenience in rapid point-of-need detection. Apart from that, there are fluorescence-based sensors for heavy water, which have been reported and are listed in Table .…”

Section: Introductionmentioning

confidence: 99%

Deep Eutectic Solvent-Based Highly Sensitive Turn-On Fluorescent Probe for D₂O

Patil,

Gupta,

Goswami

et al. 2023

ACS Omega

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Owing to the importance of heavy water in spectroscopy, nuclear energy generation, chemical characterization, and biological industry, a design of a robust, cheap, nontoxic, and sensitive D 2 O sensor is very important. In this work, taking advantage of the singular emission fluorescence of the deep eutectic solvent prepared in our laboratory, we propose a first of its kind highly sensitive turn-on fluorescent sensor to effectively sense D 2 O at an ultratrace level based on rapid exchange of the labile DES proton with deuterium. This method can be used as a full-range heavy water detection strategy with a limit of detection of 0.079% (v/v) or 870 ppm. The isotopic purity (IP) obtained from DES fluorescence measurements is also in close agreement with that of the conventional FT-IR method. The current DES-based sensor thus allows both sensing and isotopic purity of D 2 O and can serve as one of the most sensitive monitoring strategies for heavy water analysis.

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Section: Introductionmentioning

confidence: 99%

Deep Eutectic Solvent-Based Highly Sensitive Turn-On Fluorescent Probe for D₂O

Patil,

Gupta,

Goswami

et al. 2023

ACS Omega

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“…Based on its favorable traits, such as simple and controllable pretreatment steps, rapid processing of analyses and high degree of accuracy, qNMR has been applied for the quantification of many compounds 25–28 . However, it has not been widely used for the quantification of deuterated reagents other than D 2 O. Goldblatt et al 29 first applied NMR to determine the isotopic abundance of D 2 O. NMR has shown results comparable with those of MS and density methods. Ma et al 30 used a quantitative method based on 1 H NMR and 2 H NMR to directly determine deuterium concentrations in water.…”

Section: Introductionmentioning

confidence: 99%

“…for the quantification of deuterated reagents other than D 2 O. Goldblatt et al 29 first applied NMR to determine the isotopic abundance of D 2 O. NMR has shown results comparable with those of MS and density methods. Ma et al 30 used a quantitative method based on 1 H NMR and 2 H NMR to directly determine deuterium concentrations in water.…”

Section: Introductionmentioning

confidence: 99%

Determination of isotope abundance for deuterium‐labeled compounds by quantitative ¹H NMR + ²H NMR

Xie

Zhao

Sheng

et al. 2022

Labelled Comp Radiopharmac

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Deuterated reagents have been used in many research fields. Isotope abundance, as the feature parameter of deuterated reagents, the precise quantification, is of great importance. Based on quantitative nuclear magnetic resonance technology, a novel method that combines 1H NMR + 2H NMR was systematically established to determine the isotopic abundance of deuterated reagents. The results showed that the isotopic abundance of partially labeled and fully labeled compounds calculated by this new method was even more accurate than that calculated by classical 1H NMR and mass spectrometry (MS) methods. In brief, this new method is a robust strategy for the determination of isotope abundance in large‐scale deuterated reagents.

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Analyse von stabil-isotop markierten Verbindungen

Schmidt

1974

Messung Von Radioaktiven Und Stabilen Isotopen

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Determination of the Deuterium Content of a Sample of Deuterium Oxide by Three Methods.

Cited by 15 publications

References 3 publications

Deep Eutectic Solvent-Based Highly Sensitive Turn-On Fluorescent Probe for D₂O

Deep Eutectic Solvent-Based Highly Sensitive Turn-On Fluorescent Probe for D₂O

Determination of isotope abundance for deuterium‐labeled compounds by quantitative ¹H NMR + ²H NMR

Analyse von stabil-isotop markierten Verbindungen

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Determination of the Deuterium Content of a Sample of Deuterium Oxide by Three Methods.

Cited by 15 publications

References 3 publications

Deep Eutectic Solvent-Based Highly Sensitive Turn-On Fluorescent Probe for D2O

Deep Eutectic Solvent-Based Highly Sensitive Turn-On Fluorescent Probe for D2O

Determination of isotope abundance for deuterium‐labeled compounds by quantitative 1H NMR + 2H NMR

Analyse von stabil-isotop markierten Verbindungen

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Product

Resources

About

Deep Eutectic Solvent-Based Highly Sensitive Turn-On Fluorescent Probe for D₂O

Deep Eutectic Solvent-Based Highly Sensitive Turn-On Fluorescent Probe for D₂O

Determination of isotope abundance for deuterium‐labeled compounds by quantitative ¹H NMR + ²H NMR