Determination Of Sun Protection Factor By Uv-Vis Spectrophotometry

Nobre, R. S.; Fonseca, Ana Paula

doi:10.4172/hccr.1000108

Cited by 12 publications

(14 citation statements)

References 6 publications

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“…To determine the photoprotective potential according to ANVISA (Brasil, 2016) it is recommended to use an in vivo method employing healthy volunteers with different skin types Alternatively, there are in vitro methods that are based on the absorptive or reflective properties of the UV filter and can be used to evaluate the SPF. This method has been shown to be effective, fast and simple and shows good correlation with in vivo results (Yang et al, 2018;Fonseca, Rafaela, 2013;Dutra et al, 2004).…”

Section: Evaluation Of In Vitro Photoprotective Potentialmentioning

confidence: 94%

“…The in vivo method of determination of SPF is officially adopted in several countries (ANVISA, Brazil; FDA, United States; DIN, Germany; COLIPA, European Union; AAN, Australia). UV-vis spectrophotometry is an in vitro approach based on spectrophotometric analysis developed by Mansur et al (1986) for the evaluation of approximate SPF values of sunscreen products (Yang et al, 2018;Fonseca, Rafaela, 2013;Dutra et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

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A study on 2-(2’-hydroxyphenyl) benzoxazoles derivatives as potential organic UV filters, Part I

Silva

Picada

Campos

et al. 2022

Braz. J. Pharm. Sci.

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Damage resulting from the incidence of ultraviolet (UV) radiation on the skin is common nowadays, with UVB (290-320 nm) and UVA (320-400 nm) radiation responsible for photoaging, sunburn and carcinogenesis. For this reason, sunscreens represent products of growing interest to prevent such damage. However, there are few organic filters marketed worldwide with photostability and effectiveness at wavelengths greater than 340 nm (long UVA), which justifies the exploration for new compounds. In this work, we determined the photostability and sun protection factor (SPF) of three 2-(2'-hydroxyphenyl)benzoxazole derivative dyes in order to develop new organic UV filters. UV-vis spectrophotometry has high level of reproducibility when compared with in vivo human clinical methods. Solubility determinations were performed in different solvents. The compounds absorbed UVA and UVB radiation, with maximum absorption wavelengths ranging from 336 to 374 nm. Photostability was evaluated using a solar simulator (3 J.m 2 .s -1 UVA radiation) for a maximum of 3 h. The 2-(amino-2'-hydroxyphenyl)benzoxazoles showed higher photostability than the acetylated derivative under the evaluated conditions. The three benzoxazoles presented SPF values of around 40 and preliminary results indicate that they show suitable properties to act as good chemical filters in photoprotective formulations.

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Section: Evaluation Of In Vitro Photoprotective Potentialmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

A study on 2-(2’-hydroxyphenyl) benzoxazoles derivatives as potential organic UV filters, Part I

Silva

Picada

Campos

et al. 2022

Braz. J. Pharm. Sci.

View full text Add to dashboard Cite

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“…Uptake with a peak of 1636 cm -1 indicated an aromatic benzene group conjugated with alkene [7]. Based on that spectrum, the product contained ethanol was showed wave number at 3334 cm -1 .…”

Section: Jkpk (Jurnalmentioning

confidence: 95%

“…There are two types of sunscreens; organic and inorganic [6,7]. Popular choices for inorganic sunscreens are Titanium dioxide (TiO2) and Zinc oxide (ZnO).…”

Section: Introductionmentioning

confidence: 99%

Sonochemical Synthesis of Ethyl Cinnamate

Purwaningsih

Syukur

Purwanto

2020

JKPK

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<p>This research aimed to determine the yield of ethyl cinnamate synthesized by the sonochemical method and its potency as a sunscreen agent. Ethyl cinnamate was synthesized from cinnamic acid and ethanol with concentrated sulfuric acid as catalysts assisted by ultrasonic waves. The Identification of compounds was carried out by infrared spectrophotometry and gas chromatography-mass spectroscopy. Synthesis of ethyl cinnamate resulted in the form of clear yellow liquid with a fragrant aroma of a cinnamon ester with a 96.61% yield. Identification by an infrared spectrophotometer showed many functional groups of ethyl cinnamate. Identification by GC-MS was given a relative abundance of 98.96%. The product of synthesis had SPF number 4.769 at 10 ppm used Mansur Equation. Based on this research, it concluded that it has potential as a sunscreen agent. The sonochemical method provides an excellent yield of ethyl cinnamate.</p>

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“…These consist of a stratified squamous epithelial layer, with most cells being keratinocytes, which are responsible for the structural strength and permeability characteristic of this layer. In the epidermis, there are also melanocytes (melanin-producing cells, responsible for pigmentation), Langerhans cells (responsible for controlling the skin's immune responses) and Merkel cells (for detection of light touch and surface pressure) [1] .…”

Section: Introductionmentioning

confidence: 99%

Skin microbiome vs. atopic dermatitis: A review

Maia¹,

Fonseca²

2022

Int. J. Sci. Res. Arch.

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Introduction: The human skin is home-grown to an abundant colonization of bacteria, fungi and viruses. Atopic dermatitis is a chronic or recurrent and pruritic inflammatory skin disease that affects mainly the flexed areas of the skin, affecting the quality of life of the patient. People. In a situation of normal skin without pathology, the bacteria present in greater quantity are Actinobacteria and Firmicutes, and the fungi most easily found are Malassezia and Candida. Aim: This review aims to observe the relationship between the skin microbiome and atopic dermatitis as well as to verify the changes that occur at the microbiome level when faced with this pathology and treatment options. Materials and Methods: To carry out this literature review, articles were collected from “Pubmed”, “NCBI” and “Google schoolar” databases, publications dates between 2005 and 2020. Results and discussion: There are several treatment options for this disease, the use of topical corticosteroids, emollients and topical moisturizing therapy remains the therapy of choice. When an exacerbation of bacterial proliferation is observed, the use of antibiotics, namely anti-staphylococcal drugs, is advisable since there is a considerable increase in the proliferation of Staphylococcus aureus (S. aureus) throughout the course of the disease. Conclusion: According to the bibliography used, it is concluded that during the disease there is an increase in the S. aureus community as well as the loss of bacterial diversity in the skin, and the increase in S. aureus colonization is facilitated by changes that occur in it due to the presence of the pathology.

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Determination Of Sun Protection Factor By Uv-Vis Spectrophotometry

Cited by 12 publications

References 6 publications

A study on 2-(2’-hydroxyphenyl) benzoxazoles derivatives as potential organic UV filters, Part I

A study on 2-(2’-hydroxyphenyl) benzoxazoles derivatives as potential organic UV filters, Part I

Sonochemical Synthesis of Ethyl Cinnamate

Skin microbiome vs. atopic dermatitis: A review

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