Determination of SOD in black ginger extract and its effect on the liver of rats with type 2 diabetes

HUA, Li Yue; NING, Zhou; Ning, Yue-Bao

doi:10.1590/fst.115021

Cited by 4 publications

(3 citation statements)

References 11 publications

(11 reference statements)

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“…Type 2 diabetes is a common disease that can cause great harm to human health, but most western medicines for diabetes have side effects, so it is a potential to control blood sugar and relieve diabetes by extracting SDF from edible fungi (Bai et al,2021;Hua et al, 2022). Auricularia auricular polysaccharide belongs to soluble dietary fiber.…”

Section: Hypoglycemic Effect Of Edible Fungi Soluble Dietary Fibermentioning

confidence: 99%

Extraction, physiological function and application of soluble dietary fiber from edible fungi: a review

Zheng

DENG

et al. 2022

Food Sci. Technol

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The methods AOAC (Association of Official Analytical Chemists) (Tobaruela et al., 2018) 991.43 is a traditional DF analysis method, mainly analyzing insoluble and soluble higher molecular weight dietary fiber (HMWDF), while methods AOAC 2011.25 is a new dietary fiber analysis method. This method can not only analyze the content of TDF, but also the content of IDF, SDF and resistant starch (RS) (Tobaruela et al.,

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Section: Hypoglycemic Effect Of Edible Fungi Soluble Dietary Fibermentioning

confidence: 99%

Extraction, physiological function and application of soluble dietary fiber from edible fungi: a review

Zheng

DENG

et al. 2022

Food Sci. Technol

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“…Mai Dong extract [27] can reduce hepatic lipids, while Xuan Sen [28] extract suppresses the hepatic inflammation induced by a high-cholesterol diet. Other adjuvants of the LMY formula, including ginger [29,30] and Sheng Di [31], can protect hepatocytes from various types of stress. Considering that the ingredients of the LMY formula antagonize NAFLD pathologies, LMY might play an excellent role in alleviating NAFLD.…”

Section: Introductionmentioning

confidence: 99%

Lian-Mei-Yin formula alleviates diet-induced hepatic steatosis by suppressing Yap1/FOXM1 pathway-dependent lipid synthesis

Zhang,

Cao,

Liang

et al. 2024

ABBS

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Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, with a global prevalence of 25%. Patients with NAFLD are more likely to suffer from advanced liver disease, cardiovascular disease, or type II diabetes. However, unfortunately, there is still a shortage of FDA-approved therapeutic agents for NAFLD. Lian-Mei-Yin (LMY) is a traditional Chinese medicine formula used for decades to treat liver disorders. It has recently been applied to type II diabetes which is closely related to insulin resistance. Given that NAFLD is another disease involved in insulin resistance, we hypothesize that LMY might be a promising formula for NAFLD therapy. Herein, we verify that the LMY formula effectively reduces hepatic steatosis in diet-induced zebrafish and NAFLD model mice in a time-and dose-dependent manner. Mechanistically, LMY suppresses Yap1-mediated Foxm1 activation, which is crucial for the occurrence and development of NAFLD. Consequently, lipogenesis is ameliorated by LMY administration. In summary, the LMY formula alleviates diet-induced NAFLD in zebrafish and mice by inhibiting Yap1/Foxm1 signaling-mediated NAFLD pathology.

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“…S.O.D.s extracted from plants have been evaluated in human studies as interventions in different pathologies such as diseases related to oxidative stress and aging [ 1 ]. Hua et al [ 15 ] have extracted S.O.D. from black ginger and observed a protective effect on the liver of type 2 diabetic rats.…”

Section: Introductionmentioning

confidence: 99%

Optimization of Sonication Parameters to Produce a Cashew Apple Bagasse Puree Rich in Superoxide Dismutase

Fonteles

Leite

Fernandes

et al. 2022

Foods

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The effects of ultrasound processing parameters on the extraction of antioxidative enzymes and a toxicity assessment of cashew apple bagasse puree were investigated. Ultrasound directly affects the formation of reactive oxygen species such as H2O2, and consequently, superoxide dismutase, catalase, and ascorbate peroxidase activities. S.O.D. activity increased up to 280% after U.S. processing at 75 W/cm2, 1:3 bagasse: water ratio, and 10 min compared to non-processed bagasse. Therefore, the effect of ultrasound in delaying browning could be correlated to the enhanced antioxidant enzyme activity and decrease in peroxidase activity. At center point conditions (226 W/cm2, 1:3 bagasse: water ratio; 6 min), a decrease of 20% and 50% on POD and PPO activities was observed, respectively. No significant acute toxicity or protective effect was observed in unprocessed and sonicated cashew apple bagasse. Although cashew bagasse processed at 75 W/cm2 prevented nauplii death after 24 h of exposure, this data cannot assure the protective effect once the number of dead nauplii on 100 μg/mL was similar. However, these data indicate a possible protective effect, especially in higher cashew bagasse concentrations. The results suggest that sonicated cashew apple bagasse puree, a coproduct obtained from a traditional valued fruit in Brazil, may be used as a source of antioxidative enzymes, which further has great importance in therapeutics.

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Determination of SOD in black ginger extract and its effect on the liver of rats with type 2 diabetes

Cited by 4 publications

References 11 publications

Extraction, physiological function and application of soluble dietary fiber from edible fungi: a review

Extraction, physiological function and application of soluble dietary fiber from edible fungi: a review

Lian-Mei-Yin formula alleviates diet-induced hepatic steatosis by suppressing Yap1/FOXM1 pathway-dependent lipid synthesis

Optimization of Sonication Parameters to Produce a Cashew Apple Bagasse Puree Rich in Superoxide Dismutase

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