Determination of Psoralen and Isopsoralen in Traditional Chinese Medicines by Capillary Zone Electrophoresis with Amperometric Detection

Determination of Bioactive Constituents in Traditional Chinese Medicines by CE with Electrochemical Detection

“…[58]. umbelliferone in Flos Chrysanthemum [63], scopoletin in Herba Erigerontis [74], psoralen and isopsoralen in Radix Sileris, and Fructus Psoraleae [81], respectively. Because the coumarins are difficult to be oxidized, the employed detection potentials were as high as +0.95 to +1.0 V (vs. SCE) to acquire a good sensitivity.…”

“…It has been demonstrated that some Chinese herbs showed strong OH· scavenging activity that is correlated to the concentration of scavenger (i.e. the extract of TCMs Fructus Forsythiae Febrile disease, carbuncle Anti-bacteria, anti-inflammation, anti-oxidation, [71] Sophora japonica L. pericarps Hemafecia, hemorrhoid Anti-cancer, anti-oxidation [72] Sophora japonica L. seeds Hemafecia, hemorrhoid Anti-cancer, anti-oxidation [72] Flos Lonicerae Febrile disease, dysentery, sore Anti-bacteria, anti-inflammation, anti-tumor [73] Herba Erigerontis Brain and coronary diseases Anti-oxidation, antimutagen [74] Folium Apocyni Veneti Hepatopathy, insomnia, edema Anti-oxidation, anti-inflammation [75] Folium Ginkgo Coronary disease, angina, hyperlipaemia Scavenging radical, anti-oxidation [76] Radix Glycyrrhizae Infirmary, palmus, cough Detoxifcation, antiasthmatic [77] Rhizoma Gastrodiae Headache, megrim, torpidity Sedation, acesodyne [5] Herba Agrimoniae Emptysis, diarrhea, carbuncle Anti-inflammation, anti-tumor, desinsection [78] Rhizoma Curcumae Longae Chest ache, amenorrhoea Reducing fever, anti-oxidation anti-inflammation [79] Radix Salviae Miltiorrhizae Menoxenia, sore, coronarism Anti-bacteria, sedation [80] Radix Sileris Cold, rheumatism, tetanus Reducing fever, anti-bacteria [81] Fructus Psoraleae Spermatorrhea, vitligo, pelade Reducing fever, anti-bacteria, UV absorbant [81] ( Rhizoma Gastrodiae capsules Headache, megrim, torpidity Sedation, acesodyne [5] Radix Salviae Miltiorrhizae tablets Menoxenia, sore, coronarism Anti-bacteria, sedation [80] Fructus Lycii capsules Tinnitus, nervosis, hepatitis, diabetes Enhancing organism immunization depressurization, [82] Zhen Ju Jiang Ya tablet Hyperpiesis Depressing hypertension, dilating blood vessels [90] HuangdanYinchen Granule Hepatitis Antioxidation, anti-bacteria, anti-inflammation [91] …”

Simultaneous determination of psoralen and isopsoralen in plasma and Chinese medicine Xian Ling Gu Bao capsule by using HPLC-DAD coupled with alternating trilinear decomposition algorithm

“…Several methods for analyzing the presence in medicine and plasma have been reported, such as reversed-phase liquid chromatography-photodiode-array detection (RP-HPLC-DAD) [6], capillary zone electrophoresis-amperometric detection (CZE-AD) [7]. Also the method of fingerprint analysis with liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS n ) [8] has been reported so far.…”

Simultaneous determination of 10 active components in traditional Chinese medicine “YIGONG” capsule by RP-HPLC–DAD

“…According to the literature, the major constituents in YGC, such as GLY [3,4], AG [5,6], PS, IS [7,8], SC [9], IM, ISO [10,11], EM [12], OA [13], and SH [14], were reported to possess arrays of biological activities. Although HPLC methods have been applied to determine some of the constituents in crude drugs and Chinese patented medicines [15][16][17][18][19][20][21][22], no analytical method has been reported for simultaneous determination of 10 major constituents in YGC. Hence, it is very important to establish such a method for quality control of these bioactive compounds, which could help to evaluate the quality of the herbal formula.…”