“…These techniques include cell suspensions such as [3H]-thymidine (Silvestrini et al, 1989;Veneroni et al, 1988) or bromodeoxyuridine (Brd U) (Kawauchi et al, 1989;Sasaki et al, 1988;Schrape et al, 1987) labelling indices, or flow cytometric measurement of DNA content (Baisch and Gerdes, 1987;Bauer et af., 1986;Braylan and Benson, 1989;Christensson et al, 1989;Roos et al, 1985). They also concern histological sections such as counts of mitoses (Akerman et al, 1987;Donhijsen, 1987) or nucleolar organizer regions (Schrape et ai., 1987;Crocker and Nar, 1987;Hall et al, 1988a) or the counting of cells expressing a nuclear antigen present during the cell cycle (G 1, S, G2, M) as revealed by the monoclonal antibody Ki-67 (Veneroni et al, 1988;Schrape et al, 1987;Baisch and Gerdes, 1987;Hall et al, 1988a;Gerdes et al, 1983Gerdes et al, , 1984aGerdes et al, , b, 1987Hall et al, 1988b;Cibull et al, 1989;Drach et al, 1989;Schonk et al, 1989;Shirono et al, 1989;Weinberg, 1989;Weiss et al, 1987).…”