Determination of polyphenol components of Lonicera japonica Thunb. using liquid chromatography–tandem mass spectrometry: Contribution to the overall antioxidant activity

Seo, On Nuri; Kim, Gon‐Sup; Park, Semin; Lee, Jung Han; Kim, Yun‐Hi; Lee, Won Sup; Lee, Soo Jung; Kim, Chi Yeon; Jin, Jong Sung; Choi, Sang Kyung; Shin, Sung Chul

doi:10.1016/j.foodchem.2012.02.124

Cited by 89 publications

(68 citation statements)

References 25 publications

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“…Tyrosine (4), guanosine (5), adenosine (6), vanillic acid (8), protocatechuic acid (13), loganic acid (17), salicylic acid (19), caffeic acid (26) …”

Section: Chemical Regents and Materialsmentioning

confidence: 99%

Comprehensive identification of 125 multifarious constituents in Shuang–huang–lian powder injection by HPLC-DAD-ESI-IT-TOF-MS

Sun

Liu

Lin

et al. 2015

Journal of Pharmaceutical and Biomedical Analysis

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“…Tyrosine (4), guanosine (5), adenosine (6), vanillic acid (8), protocatechuic acid (13), loganic acid (17), salicylic acid (19), caffeic acid (26) …”

Section: Chemical Regents and Materialsmentioning

confidence: 99%

Comprehensive identification of 125 multifarious constituents in Shuang–huang–lian powder injection by HPLC-DAD-ESI-IT-TOF-MS

Sun

Liu

Lin

et al. 2015

Journal of Pharmaceutical and Biomedical Analysis

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“…For the contents of flavonoids (rutin and luteoloside), no significant influence was observed with sulfur fumigating for LJF. As the literature displayed, the main o-diphenolic compounds in LJF were chlorogenic acid and isochlorogenic acids [24]. The polyphenol oxidase (PPO) enriched in the damaged tissues of fresh LJF, which oxidize caffeoylquinic acids to pigments in processing, is involved in the enzymatic browning leading to severe loss of this type of compound [25].…”

Section: Quantification Of Main Phenolic Acids Flavonoids and Iridoimentioning

confidence: 99%

Influence of Sulfur Fumigation on the Chemical Constituents and Antioxidant Activity of Buds of Lonicera japonica

et al. 2014

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Lonicera japonica flos is widely used as a pharmaceutical resource and a commonly-employed ingredient in healthy food, soft beverages and cosmetics in China. Sometimes, sulfur fumigation is used during post-harvest handling. In this study, a comprehensive comparison of the chemical profile between sun-dried and sulfur-fumigated samples was conducted by HPLC fingerprints and simultaneous quantification of nine constituents, including secologanic acid, along with another eight usually-analyzed markers. Secologanic acid was destroyed, and its sulfonates were generated, whereas caffeoylquinic acids were protected from being oxidized. The residual sulfur dioxide in sulfur-fumigated samples was significantly higher than that in sun-dried samples, which might increase the potential incidence of toxicity to humans. Meanwhile, compared with sun-dried samples, sulfur-fumigated samples have significantly stronger antioxidant activity, which could be attributed to the joint effect of protected phenolic acids and flavonoids, as well as newly-generated iridoid sulfonates.

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“…While, Peak 12 was assigned as kaempferol‐3‐O‐glucoside due to the similar fragmentation pattern with reference (Sun, Liu, Yang, Slovin, & Chen, ). These compounds have been identified in the ingredients of ARFT (Seo et al, ; Zheng, Pan, Cai, Yuan, & Gao, ).…”

Section: Resultsmentioning

confidence: 99%

Antioxidant activity, α-glucosidase inhibition, and phytochemical fingerprints ofAnoectochilus roxburghiiformula tea residues with HPLC-QTOF-MS/MS

Xie

Zhang

et al. 2017

J Food Biochem

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This study assessed the phytochemical composition, antioxidant activities, and α‐glucosidase inhibition of Anoectochilus roxburghii formula tea (ARFT) residue by comparing with that of ARFT infusion and ARFT extract. ARFT residue extract showed the maximum total phenolics, total flavonoids, and total condensed tannins content, with the values of 146.70 GAE mg/g E, 58.50 QE mg/g E, and 312.08 mg CE/g E, respectively, while ARFT infusion exhibited the lowest values. The strongest ABTS+· scavenging ability and α‐glucosidase inhibition were also found in ARFT residue extract, but the best DPPH· scavenging ability was observed on the 95% ethanol extract of ARFT. Totally, 29 compounds were tentatively identified from the ARFT residue extract by using HPLC‐QTOF‐MS/MS, including 2 organic acids, 17 flavonoids, 4 fatty acids, 5 saponins, and 1 sugar. The results indicated that ARFT residue can be a promising source of natural antioxidants and α‐glucosidase inhibitors. Practical applications Anoectochilus roxburghii formula tea (ARFT) is a popular health‐promoting tea in China, but research on the bio‐activities and functional constitution of ARFT and its residues is not available. This study suggested promising antioxidant and α‐glucosidase inhibition of ARFT residue and revealed the presence of 29 major phytochemical compounds, which indicated that ARFT residue can be a potential resource of natural antioxidants and α‐glucosidase inhibitors in food, cosmetic, and pharmaceutical industry.

show abstract

Determination of polyphenol components of Lonicera japonica Thunb. using liquid chromatography–tandem mass spectrometry: Contribution to the overall antioxidant activity

Cited by 89 publications

References 25 publications

Comprehensive identification of 125 multifarious constituents in Shuang–huang–lian powder injection by HPLC-DAD-ESI-IT-TOF-MS

Comprehensive identification of 125 multifarious constituents in Shuang–huang–lian powder injection by HPLC-DAD-ESI-IT-TOF-MS

Influence of Sulfur Fumigation on the Chemical Constituents and Antioxidant Activity of Buds of Lonicera japonica

Antioxidant activity, α-glucosidase inhibition, and phytochemical fingerprints ofAnoectochilus roxburghiiformula tea residues with HPLC-QTOF-MS/MS

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