Determination of Plasma Osteopontin and Serum Inhibin B in Pregnant Women with Preeclampsia

Abstract

Pre-eclampsia is a multisystem disorder of pregnancy, which complicates 3%-5% of pregnancies in the world .The present study deals with estimation of levels of Osteopontin, Inhibin B, protein, albumin, globulin and Alb./Glb. ratio in forty five Pregnant Women with Preeclampsia in comparison with thirty healthy Pregnant Women. In Pregnant Women with Preeclampsia, the level of Osteopontin and Inhibin B were significantly higher as compared to the normal subjects [p<0.01]. In Pregnant Women with Preeclampsia the levels of S. calcium S.Protein and albumin were significantly decreased as compared to the normal subjects [p<0.05, p<0.05and p<0.01] respectively. Based on findings of the present study, it can be concluded that Patients with Preeclampsia had significantly higher serum inhibin B and Osteopontin concentrations compared to healthy pregnant women. In addition, the current study could not determine any links between Osteopontin levels and other biochemical markers in this study.

Evalution of Inhibin B and some Sexual Hormones Levels in men with Atherosclerosis Kirkuk city

“…The determination serum Inhibin B by Enzyme Linked Immunosorbent Assay (ELISA) [Ray Biotech, Inc [8]. Testosterone Serum testosterone concentration was determined according to the method of Wilke and Utley [9] using ELISA (Enzyme Linked Immuno Sorbant Assay).…”