This study was designed to show, the role of Carthamus tinctorius safflower aqueous extract against toxicity of nickel chloride (NiCl 2 ). Twenty male, rabbits were used and divided into four groups (with 5 rabbits in each group); group (control group) received normal diet, group II received orally 100mg/kg NiCl 2 for six weeks, group III received 100mg/kg NiCl 2 and 100mg/kg extract six weeks, group IV received 100mg/kg NiCl 2 and 200mg/ kg extract six weeks. Hematological parameters showed (RBC (Red blood cells), Hb (Hemoglobin), PCV (Packed cells volume) decreased and WBC (White blood cells) increased) significant changes (P < 0.05) compared with control group. Immunological parameters (IgG, IgA and IgM increased) and oxidative stress factors (MDA increased and GSH decreased) show significant changes (P < 0.05) compared with control group. While, safflower aqueous adverse the negative effects of NiCl 2 and causing ameliorative effects on all hematological parameters, hematological immunological parameters and oxidative stress factors showed no significant changes (P < 0.05) compared with control group. It was concluded that flower extract of Carthamus tinctorius has been antioxidant role against nickel chloride toxicity in rabbits.
The study designed to evaluate the inhibin B and sexual hormones levels with atherosclerosis. One hundred volunteers resecived at private laboratory between 4/2017 to 7/2017in Kirkuk city (eighty volunteers with atherosclerosis and twenty apparently healthy subjects) were used. Then, volunteers divided to two groups. The first group was including apparently healthy and the second group was including patients (Wt:70-90 kg and age average 50-65 years). Laboratory diagnosis showed a decrease in inhibin B, Testosterone, Lutenizing hormone (LH) follicle stimulating hormone (FSH) in patient group. Moreover, all parameter levels showed significant (P<0.05) decrease in all patients compare with all healthy subject group. It was concluded from this study that the atherosclerosis may led to decrease in an inhibin B and sexual hormones levels.
This study aimed to estimate the level of leptin hormone and some biochemical variables in patients with lung cancer. Twenty five patients with lung cancer and 24 healthy control were enrolled in this study. The results showed a significant decrease in the level of leptin in patients with lung cancer compared to healthy control. In group of patients with lung cancer who had BMI ( 20 -23 kg/m 2 ), ( 24-26 kg/m 2 ), ( more than 30 kg/m 2 ) the levels of leptin were (1.42 ± 0.54), (4.35 ± 2.19), (8.75 ± 1.2) ng/ml respectively, comparing with the healthy control (4.89 ± 1.29), (6.85 ± 1.49), (9.85 ± 2.62) ng/ml respectively. The results also showed that there was a significant increase in activity of ALT in patients group (30.8 ± 16.4) U/L compared to healthy control (22.8 ± 6.55), while there was no statistically significant differences in the activity of AST in patients group (25.4 ± 8.9) U/L compared to healthy control (27 ± 9.2). There were no statistically significant correlation between leptin level with ALT ( r = -0.104 ) and AST ( r = 0.092 ).
The current study was conducted from April 19 to May 29, 2021 Public Health department, Animal Origin Division, in the Kirkuk Health department in Kirkuk city to study the causes and spread of infections recorded for period from 2016-2019 in Kirkuk Governorate, 67 cases were diagnosed according to the months,. The highest infection recorded in 2019 was (26) 38.80% and the lowest infection was (10) 14.92% in each of 2016 and 2017 years. The group of health sectors showed the cyst disease caused by strays dogs, which is one of environmental pollutants, where Kirkuk First sector recorded the highest infection (31) 44.77%, while Hawija First sector recorded the lowest infection (4) 5.97%. The study recorded that the percentage of infection among females was 68.65%, and it was more than males 31.34%. The age group 15-25 years showed the highest number of injuries (46), with a rate of 68.65% of injuries during the years.
The current study was used 20 male rabbits that divided into four groups (consist of five rabbits in each group), The first group was considered as control and fed normal diet and given tap water, The second group was consisted of rabbits that fed on high cholesterol diet for six weeks, The third group was consisted of rabbits that fed on high cholesterol diet and 50mg root extract for six weeks, The forth group was consisted of rabbits that fed on high cholesterol diet and 100mg root extract for six weeks. The male rabbits that feeding on high cholesterol diet showed significant increased (P < 0.05) the levels of cholesterol, triglyceride, LDL, VLDL, MDA and HMG-CoA reductase while HDL and GSH levels were significantly decreased (P < 0.05) compared with to control group. It was concluded from this study that root extract has amply good effective role on hyperlipidemia of male rabbits.
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The present study used 20 male rabbits that divided randomly to four groups (each group consist 5 rabbits), control group received only normal diet, the group received carbon tetrachloride (CCL 4 ) for forty days, the group treated (orally) with carbon tetrachloride and (100mg/per day) root extract for forty days, the fourth treated with carbon tetrachloride and (200mg/per day) root extract for forty days. the rabbits that treated with carbon tetrachloride showed decreased in the counts, motility, number of living sperms and increased the deformity of sperms with decreased the levels of LH, FSH and testosterone show high significant changes (P <0.05) compare with control. In contrast, these parameters still normal when the groups that administrated with Panax ginseng root extract. It was concluded that the root extract play important role against heavy metals that causes fertility of male rabbits.
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