Determination of phenolic acids in Prunella vulgaris L.: a safe and green extraction method using alcohol-based deep eutectic solvents

Xia, Bo‐Hou; Yan, Dong; Bai, Yubing; Xie, Jiachi; Cao, Yi; Liao, Duan‐Fang; Lin, Limei

doi:10.1039/c5ay02035b

Cited by 60 publications

(21 citation statements)

References 39 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…An increased amount of rosmarinic acid was obtained with a higher addition of H 2 O, but increased temperature showed an important influence only in the experiment with 10% of H 2 O (v/v) probably due to lower viscosity at higher temperatures. This was also determined with alcohol-based deep eutectic solvents, where 40% of H 2 O provided the highest yield of rosmarinic acid, but the yield was higher at higher temperatures in all experiments [52]. In a paper by Duan et al [53], DESs with different HBAs were prepared for polyphenol extraction, and ChCl-based DESs proved to be more suitable for rosmarinic acid extraction than Bet-and Pro-based DESs.…”

Section: Comparison Of the Possibility Of Extraction By Dessmentioning

confidence: 70%

Application of Deep Eutectic Solvents for the Extraction of Rutin and Rosmarinic Acid from Satureja montana L. and Evaluation of the Extracts Antiradical Activity

Jakovljević

Vladić

Vidović

et al. 2020

Plants

View full text Add to dashboard Cite

Satureja montana L. was used in the current research as the plant exhibits numerous health-promoting benefits due to its specific chemical composition. The extraction method based on deep eutectic solvents (DESs) was used for the extraction of rutin and rosmarinic acid from this plant. Five different choline chloride-based DESs with different volumes of water (10%, 30%, and 50% (v/v)) were used for the extraction at different temperatures (30, 50, and 70 °C) to investigate the influence on rosmarinic acid and rutin content obtained by high-performance liquid chromatography with diode-array detector (HPLC-DAD) in the obtained extracts. A principal component analysis was employed to explore and visualize the influence of applied parameters on the efficiency of the extraction procedure of rutin and rosmarinic acid. Among the tested DESs, choline chloride:lactic acid (mole ratio 1:2) and choline chloride:levulinic acid (mole ratio 1:2) were the most suitable for the extraction of rutin, while for rosmarinic acid choline chloride:urea (mole ratio 1:2) was the most effective solvent. The extract showing the best antiradical activity was obtained with choline chloride:urea (mole ratio 1:1) at 30 °C and 50% H2O (v/v).

show abstract

Section: Comparison Of the Possibility Of Extraction By Dessmentioning

confidence: 70%

Application of Deep Eutectic Solvents for the Extraction of Rutin and Rosmarinic Acid from Satureja montana L. and Evaluation of the Extracts Antiradical Activity

Jakovljević

Vladić

Vidović

et al. 2020

Plants

View full text Add to dashboard Cite

show abstract

“…Za razliku od drugih eutektičkih smjesa s kolin kloridom, kolin klorid/etilen glikol ima nisku viskoznost, kao posljedica velikog broja vodikovih veza između komponenti otapala, van der Waalsovih sila između molekula te veličine iona. 19 Taj DES se pokazao dobrim otapalom za acetaminofen, komponentu s analgetičkim i antipiretičkim djelovanjem 21 kao i dobro otapalo za ekstrakciju fenolnih spojeva u lišću masline, 22 fenolnih spojeva u kori citrusa, 23 rosmarinske kiseline i rosmarinske kiselina-3'-glukozida iz obične celinščice (Prunella vulgaris L.) 24 te katehina iz zelenog čaja. 25 Također, u našim prethodnim istraživanjima, gdje su fenolne komponente ekstrahirane uz pomoć vode u subkritičnom stanju 10 ili ekstrakcijom potpomognutom ultrazvukom, 7 pokazano je da je refabrikat, kao vrsta duhanskog industrijskog otpada najbogatiji ciljanim bioaktivnim spojevima.…”

Section: P2unclassified

Ekstrakcija bioaktivnih spojeva iz duhanskog otpada primjenom eutektičkih otapala

Banožić¹,

Agronomy

Šafranko

et al. 2020

Kem. ind. (Online)

View full text Add to dashboard Cite

Duhanski otpad je kruti otpad, a njegove vrste međusobno se razlikuju po granulaciji i mjestu izdvajanja u procesu proizvodnje. Cilj ovog rada bio je istražiti učinkovitost eutektičkih otapala u ekstrakciji bioaktivnih komponenti iz duhanskog industrijskog otpada (refabrikat, rebro i prašina). Ispitan je utjecaj procesnih parametara (vrijeme miješanja, temperatura i udio vode u otapalu) na svojstva samog ekstrakta (ukupne fenole, antiradikalnu aktivnost, udio klorogenske kiseline i rutina). Metodom odzivne površine određeni su optimalni parametri ekstrakcije (30 min, 70 °C, 29,99 % vode). Provedeno istraživanje ogleda se u maksimalnom iskorištavanju nusproizvoda duhanske industrije, a rezultira visokovrijednim ekstraktima koji se mogu implementirati u druge procese i proizvode.

show abstract

“…They were recognized as a promising solvent in extraction and separation processes [ 23 ]. Until now, DESs have been widely used in the extraction of bioactive compounds in Chinese herbal medicine, such as polyphenols [ 24 , 25 , 26 ], flavonoids [ 27 , 28 ] and alkaloids [ 29 , 30 ]. DESs are mostly hydrophilic, and hydrophobic DESs were first reported in 2015 [ 31 ].…”

Section: Introductionmentioning

confidence: 99%

Optimization of Extraction of Bioactive Compounds from Baphicacanthus cusia Leaves by Hydrophobic Deep Eutectic Solvents

Cai

et al. 2021

Molecules

View full text Add to dashboard Cite

Deep eutectic solvents (DESs) are considered as efficient and green solvents for the extraction of bioactive compounds from medicinal plants. In this work, a novel method of DES-based ultrasound-assisted extraction of bioactive compounds from Baphicacanthus cusia leaves (BCL) was established. Systematic screening and the morphology of the original and treated BCL were observed with scanning electron microscopy to determine the extraction efficiency of different solvents. The extraction conditions were optimized by Box–Behnken design (BBD) tests and the optimal extraction conditions were as follows: lactic acid/L-menthol ratio of 5: 2 (mol/mol), solid–liquid ratio of 80.0 mL/g and temperature of 60.5 °C. The extraction yields of tryptanthrin, indigo and indirubin reached 0.356, 1.744 and 0.562 mg/g, respectively. The results of a 2,2-diphenyl-1-picrylhydrazy (DPPH) radical scavenging activity test indicated the feasibility of DESs in the extraction of bioactive compounds. This study indicated that L-menthol/lactic acid was a green and efficient solvent for the extraction of bioactive compounds from BCL, and DES-based ultrasound-assisted extraction could be used as an effective application strategy for the extraction of bioactive compounds from medicinal plants.

show abstract

Determination of phenolic acids in Prunella vulgaris L.: a safe and green extraction method using alcohol-based deep eutectic solvents

Abstract: The extraction of natural products with available green and safe solvents is rather limited.

Cited by 60 publications

References 39 publications

Application of Deep Eutectic Solvents for the Extraction of Rutin and Rosmarinic Acid from Satureja montana L. and Evaluation of the Extracts Antiradical Activity

Application of Deep Eutectic Solvents for the Extraction of Rutin and Rosmarinic Acid from Satureja montana L. and Evaluation of the Extracts Antiradical Activity

Ekstrakcija bioaktivnih spojeva iz duhanskog otpada primjenom eutektičkih otapala

Optimization of Extraction of Bioactive Compounds from Baphicacanthus cusia Leaves by Hydrophobic Deep Eutectic Solvents

Contact Info

Product

Resources

About