Determination of Optimum Combination of Voxel Size and b-value for Brain Diffusion Tensor Imaging

Taib, Nur Hartini Mohd; Abdullah, Wan Ahmad Kamil Wan; Shuaib, Ibrahim Lutfi; Magosso, Enrico; Isa, Suzana Mat

doi:10.17576/jsm-2017-4601-09

“…The balance of the trade-off between acquisition time and imaging resolution was shifted toward lower imaging resolution to decrease the acquisition time. Thus, we used 2.5 mm 3 as the isotropic voxel size, which is an acceptable protocol ( Mohd Taib et al, 2017 ). Fifth, the optimal ODI threshold of 0.45 was only calibrated for the CST.…”

Section: Discussionmentioning

confidence: 99%

Exploring Peritumoral Neural Tracts by Using Neurite Orientation Dispersion and Density Imaging

Chong

¹

,

Liu

²

,

Kao

³

et al. 2021

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Diffusion Tensor Imaging (DTI) tractography has been widely used in brain tumor surgery to ensure thorough resection and minimize functional damage. However, due to enhanced anisotropic uncertainty in the area with peritumoral edema, diffusion tractography is generally not practicable leading to high false-negative results in neural tracking. In this study, we evaluated the usefulness of the neurite orientation dispersion and density imaging (NODDI) derived tractography for investigating structural heterogeneity of the brain in patients with brain tumor. A total of 24 patients with brain tumors, characterized by peritumoral edema, and 10 healthy counterparts were recruited from 2014 to 2021. All participants underwent magnetic resonance imaging. Moreover, we used the images obtained from the healthy participants for calibrating the orientation dispersion threshold for NODDI-derived corticospinal tract (CST) reconstruction. Compared to DTI, NODDI-derived tractography has a great potential to improve the reconstruction of fiber tracking through regions of vasogenic edema. The regions with edematous CST in NODDI-derived tractography demonstrated a significant decrease in the intracellular volume fraction (VFic, p < 0.000) and an increase in the isotropic volume fraction (VFiso, p < 0.014). Notably, the percentage of the involved volume of the concealed CST and lesion-to-tract distance could reflect the motor function of the patients. After the tumor resection, four patients with 1–5 years follow-up were showed subsidence of the vasogenic edema and normal CST on DTI tractography. NODDI-derived tractography revealed tracts within the edematous area and could assist neurosurgeons to locate the neural tracts that are otherwise not visualized by conventional DTI tractography.

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“…Previous studies on optimal b value are mainly focused on the low field strength. Taib et al [ 9 ] also evaluated the imaging quality from the aspects of image quality (SNR) and data quality (FA, MD). However, the number of b values set in their study was relatively less ( b = 700, 1000, and 1200 s/mm 2 ), and only SNR, FA, and MD were assessed.…”

Section: Discussionmentioning

confidence: 99%

“…Sakai et al [ 8 ] evaluated the DTI imaging quality of lumbar nerve root at b = 200, 400, and 800 s/mm 2 by using 1.5 T MRI and reported the less distortion of DTI images at 400 s/mm 2 . Taib et al [ 9 ] performed a human whole brain DTI at 1.5 T scanner and used two settings of voxel size: 2.0 × 2.0 × 2.0 mm 3 and 2.5 × 2.5 × 2.5 mm 3 . Six sets of parameter settings were formed under three b values: 700, 1000, and 1200 s/mm 2 .…”

Section: Introductionmentioning

confidence: 99%

Effect of $b$ Value on Imaging Quality for Diffusion Tensor Imaging of the Spinal Cord at Ultrahigh Field Strength

Bao

¹

,

Zhao

²

,

Bao

³

et al. 2021

BioMed Research International

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Objective. To explore the optimal b value setting for diffusion tensor imaging of rats’ spinal cord at ultrahigh field strength (7 T). Methods. Spinal cord diffusion tensor imaging data were collected from 14 rats (5 healthy, 9 spinal cord injured) with a series of b values (200, 300, 400, 500, 600, 700, 800, 900, and 1000 s/mm2) under the condition that other scanning parameters were consistent. The image quality (including image signal-to-noise ratio and image distortion degree) and data quality (i.e., the stability and consistency of the DTI-derived parameters, referred to as data stability and data consistency) were quantitatively evaluated. The min-max normalization method was used to process the calculation results of the four indicators. Finally, the image and data quality under each b value were synthesized to determine the optimal b value. Results. b = 200 s / m m 2 and b = 900 s / m m 2 ranked in the top two of the comprehensive evaluation, with the best image quality at b = 200 s / m m 2 and the best data quality at b = 900 s / m m 2 . Conclusion. Considering the shortcomings of the ability of low b values to reflect the microstructure, b = 900 s / m m 2 can be used as the optimal b value for 7 T spinal cord diffusion tensor scanning.

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Analysis of genu and splenium of the corpus callosum: comparison between healthy subjects with and without Leukoaraiosis

Salbinih

¹

,

Taib

²

,

Mustapha

³

et al. 2019

J. Phys.: Conf. Ser.

0

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The purpose of this study to investigate whether there are any differences in Diffusion Tensor Imaging (DTI) values in subjects that have leukoaraiosis (LA) in the frontal white matter (fWM) and occipital white matter (oWM) compared to subjects that have no LA in those areas in the brain. DTI indices namely axial diffusivity (AD), radial diffusivity (RD), mean diffusivity (MD), fractional anisotropy (FA) were measured via retrospective study. Finding from this study shows that there is no significant difference in AD, RD, MD, and FA values between both groups. It is concluded that there are no significant differences in DTI values of genu and splenium of the corpus callosum between subjects with and without LA. This study shows that subjects with LA does not having degeneration on fiber bundles of the genu and splenium, in which the genu and splenium function in connecting right and left of hemisphere. Also, it might does not affect or not yet affect the genu and splenium fiber bundles. This finding the differences is important to determine whether any changes in AD and RD values.

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Determination of Optimum Combination of Voxel Size and b-value for Brain Diffusion Tensor Imaging

Abstract: Optimum combination of voxel size resolution and b-value for whole brain imaging has been determined. Data images were acquired using a 1.5T magnetic resonance imaging (MRI) system (GE Signa HDxt

Cited by 4 publications

References 22 publications

Exploring Peritumoral Neural Tracts by Using Neurite Orientation Dispersion and Density Imaging

Exploring Peritumoral Neural Tracts by Using Neurite Orientation Dispersion and Density Imaging

Effect of $b$ Value on Imaging Quality for Diffusion Tensor Imaging of the Spinal Cord at Ultrahigh Field Strength

Analysis of genu and splenium of the corpus callosum: comparison between healthy subjects with and without Leukoaraiosis

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Determination of Optimum Combination of Voxel Size and b-value for Brain Diffusion Tensor Imaging

Abstract: Optimum combination of voxel size resolution and b-value for whole brain imaging has been determined. Data images were acquired using a 1.5T magnetic resonance imaging (MRI) system (GE Signa HDxt

Cited by 4 publications

References 22 publications

Exploring Peritumoral Neural Tracts by Using Neurite Orientation Dispersion and Density Imaging

Exploring Peritumoral Neural Tracts by Using Neurite Orientation Dispersion and Density Imaging

Effect of b Value on Imaging Quality for Diffusion Tensor Imaging of the Spinal Cord at Ultrahigh Field Strength

Analysis of genu and splenium of the corpus callosum: comparison between healthy subjects with and without Leukoaraiosis

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Effect of $b$ Value on Imaging Quality for Diffusion Tensor Imaging of the Spinal Cord at Ultrahigh Field Strength