Determination of fluoroquinolones in the environmental samples using vortex assisted dispersive liquid-liquid microextraction coupled with high performance liquid chromatography

Selahle, Shirley Kholofelo; Nomngongo, Philiswa N.

doi:10.1080/03067319.2019.1636042

Cited by 21 publications

(8 citation statements)

References 41 publications

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“…The method was based on dispersive magnetic solid-phase extraction (DMSPE) based on the previously reported MMPC/CycChit adsorbent combined with high-performance liquid chromatography with diode array detection (HPLC-DAD). The choice of analytes to be investigated was based on the previous studies which revealed that anticonvulsants, beta-blockers, parabens and fluoroquinolones (FQs) are frequently detected in South African water systems [ 7 , 31 , 36 , 44 , 45 ]. The experimental factors (mass of adsorbent, eluent type, eluent volume, extraction time, desorption time and sample pH) affecting the extraction and preconcentration procedure were optimized using univariate and multivariate approaches.…”

Section: Introductionmentioning

confidence: 99%

Magnetic Mesoporous Carbon/β-Cyclodextrin–Chitosan Nanocomposite for Extraction and Preconcentration of Multi-Class Emerging Contaminant Residues in Environmental Samples

2021

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This study reports the development of magnetic solid-phase extraction combined with high-performance liquid chromatography for the determination of ten trace amounts of emerging contaminants (fluoroquinolone antibiotics, parabens, anticonvulsants and β-blockers) in water systems. Magnetic mesoporous carbon/β-cyclodextrin–chitosan (MMPC/Cyc-Chit) was used as an adsorbent in dispersive magnetic solid-phase extraction (DMSPE). The magnetic solid-phase extraction method was optimized using central composite design. Under the optimum conditions, the limits of detection (LODs) ranged from 0.1 to 0.7 ng L−1, 0.5 to 1.1 ng L−1 and 0.2 to 0.8 ng L−1 for anticonvulsants and β-blockers, fluoroquinolone and parabens, respectively. Relatively good dynamic linear ranges were obtained for all the investigated analytes. The repeatability (n = 7) and reproducibility (n = 5) were less than 5%, while the enrichment factors ranged between 90 and 150. The feasibility of the method in real samples was assessed by analysis of river water, tap water and wastewater samples. The recoveries for the investigated analytes in the real samples ranged from 93.5 to 98.8%, with %RSDs under 4%.

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Section: Introductionmentioning

confidence: 99%

Magnetic Mesoporous Carbon/β-Cyclodextrin–Chitosan Nanocomposite for Extraction and Preconcentration of Multi-Class Emerging Contaminant Residues in Environmental Samples

2021

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“…The structural formula of ciprofloxacin is provided in Figure 1 [3]. Several analytical methods have been reported for the quantification of ciprofloxacin, including high-performance liquid chromatography (HPLC) [4,5], spectrofluorometry [6], flow injection analysis [7], voltammetry [8], derivative spectrophotometric methods [9], titrimetric and spectrophotometric techniques using cerium (IV) sulfate [10], and various other spectrophotometric techniques [11,12]. Some studies have focused on the development of spectrophotometric methods based on charge-transfer complexation techniques [13], indirect spectrophotometric determination using N-Bromosuccinimide and Janus Green B dye [14], and the use of capillary electrophoresis with transient pseudo-isotachophoresis [11,12,15].…”

Section: Introductionmentioning

confidence: 99%

Spectrophotometric Method for the Determination of Ciprofloxacin in Pure and Pharmaceutical Preparations: Development and Validation

Mahmoud,

Hamza,

Jarallah

2024

RAiSE-2023

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“…As a result, laboratories are focusing on developing new, simple but sensitive and precise methods for the determination of hazardous compounds in food [ 12 , 13 , 14 ]. Several methods for the determination of FQLs in different matrices based on HPLC-UV (in plasma [ 9 , 15 , 16 ], urine [ 15 , 16 ] and wastewaters [ 17 ]) or LC-MS (in animal products [ 18 , 19 ] and wastewaters [ 8 , 20 ]) techniques were developed. The CE technique was also used for the determination of FQLs in water [ 21 ] or in water, urine and milk [ 22 ].…”

Section: Introductionmentioning

confidence: 99%

The Use of Extraction on C18-Silica-Modified Magnetic Nanoparticles for the Determination of Ciprofloxacin and Ofloxacin in Meat Tissues

Kośka,

Kubalczyk,

Cichomski

et al. 2023

Molecules

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A simple, fast, and low-cost method of extraction using magnetic nanoparticles was developed for sample preparation in the determination of ciprofloxacin and ofloxacin in meat tissues with the use of capillary electrophoresis. This study is the first utilization of silica-coated magnetic nanoparticles with attached C18 chains to extract fluoroquinolones from meat tissues. This method is therefore characterized by a very simple sample preparation procedure, but on the other hand, by satisfactory precision and accuracy. Magnetic nanoparticles with an appropriately modified surface were placed in an Eppendorf tube, then conditioned with methanol, next rinsed with water and, finally, a homogenized tissue sample was added. At the neutral pH of the sample solution, these compounds do not have a charge and are able to adsorb on the modified particles. After extraction, the nanoparticles were dried and, then, desorption of analytes was conducted with the use of a mixture of 0.1 mol/L HCl and acetonitrile (1:1). This approach made it possible to purify the sample matrix and to obtain satisfactory LOQ levels for the method using the CE technique with UV-Vis detection. In this method, the LOD and LOQ values for both analytes were 0.04 nmol/g tissue and 0.15 nmol/g tissue, respectively. The calibration curves were linear in the entire concentration range, and the accuracy and the recovery of the method were at the satisfactory levels. The square value of the linear correlation coefficients (R2) for Cpx and Ofx were 0.9995 and 0.9992, respectively. The precision value of the method was within the range of 3–11% and accuracy was in the range of 93–110%.

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Determination of fluoroquinolones in the environmental samples using vortex assisted dispersive liquid-liquid microextraction coupled with high performance liquid chromatography

Cited by 21 publications

References 41 publications

Magnetic Mesoporous Carbon/β-Cyclodextrin–Chitosan Nanocomposite for Extraction and Preconcentration of Multi-Class Emerging Contaminant Residues in Environmental Samples

Magnetic Mesoporous Carbon/β-Cyclodextrin–Chitosan Nanocomposite for Extraction and Preconcentration of Multi-Class Emerging Contaminant Residues in Environmental Samples

Spectrophotometric Method for the Determination of Ciprofloxacin in Pure and Pharmaceutical Preparations: Development and Validation

The Use of Extraction on C18-Silica-Modified Magnetic Nanoparticles for the Determination of Ciprofloxacin and Ofloxacin in Meat Tissues

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