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“…2 ) associated predominantly with the presence of water and ethanol in the sanitizer composition. The root mean square error of prediction (RMSEP) values obtained after model validation were improved when compared to those obtained previously by using NIRS and an instrument significantly more expensive [14] .…”
Section: Resultsmentioning
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“…2 ) associated predominantly with the presence of water and ethanol in the sanitizer composition. The root mean square error of prediction (RMSEP) values obtained after model validation were improved when compared to those obtained previously by using NIRS and an instrument significantly more expensive [14] .…”
Section: Resultsmentioning
“…The literature lacks in describing direct analytical methods for quality control of the composition of ethanol-based sanitizers. So far, only one communication very recently published on-line describes the determination of ethanol in hand sanitizers using infrared (IR) and near-infrared spectroscopy (NIRS) [14] . This communication attempted to determine the ethanol content of sanitizers neglecting the effect of interferents and employing costly NIRS instrumentation (above US$ 20,000), which restricts their extensive use by small companies and by inspection agencies.…”
Section: Introductionmentioning
“…Other analytical methods used for the determination of alcohols in ABHRs include Fourier transformed infrared spectroscopy for gel-based hand sanitisers. 16 Most of the products analysed contained ethanol as their active ingredient, with only two found to contain isopropanol and one product contained a mixture of ethanol and isobutanol. Ethanol was the preferred alcohol over propanols for ABHR formulations because of its superior virucidal activity and its skin tolerance.…”
Section: Discussionmentioning
“…Products formulated with alcohol levels close to the 60% lower limit risk the active ingredient content falling below the threshold during processing, transport, storage or use as constituent alcohols may evaporate. Post market surveillance reports by regulatory authorities in a number of countries have found some products with alcohol assays below threshold limits [ 12 , 13 ].…”
Section: Faces Of the Tetrahedron: Inputsmentioning