Determination of Elastic Modulus of Gelatin Gels by Indentation Experiments

Czerner, Marina; Fellay, Lucas Sanchez; Suárez, M.P.; Frontini, Patricia María; Fasce, Laura Alejandra

doi:10.1016/j.mspro.2015.04.075

Cited by 97 publications

(65 citation statements)

References 5 publications

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“…Unlike most dilute mucous gels, it is stiff, with an average elastic modulus of 30 kPa (Wilks et al 2015). This is stiffer than 7% gelatin and approaches the stiffness of 20% gelatin (Eysturskard et al 2009; Czerner et al 2015). Unlike gelatin and other stiff gels, however, slug glue can be stretched over ten times its initial length (Wilks et al 2015).…”

Section: Introductionmentioning

confidence: 78%

RNA-Seq reveals a central role for lectin, C1q and von Willebrand factor A domains in the defensive glue of a terrestrial slug

et al. 2017

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The tough, hydrogel glue produced by the slug Arion subfuscus achieves impressive performance through metal-based, protein cross-links. The primary sequence of these proteins was determined through transcriptome sequencing and proteome analysis by tandem mass spectrometry. The main proteins that correlate with adhesive function are a group of eleven small, highly abundant lectin-like proteins. These proteins matched the ligand-binding C-lectin, C1q or H-lectin domains. The variety of different lectin-like proteins and their potential for oligomerization suggests that they function as versatile and potent cross-linkers. In addition, the glue contains five matrilin-like proteins that are rich in von Willebrand Factor A (VWA) and EGF domains. Both C-lectins and VWA domains are known to bind to ligands using divalent cations. These findings are consistent with the double network mechanism proposed for slug glue, with divalent ions serving as sacrificial bonds to dissipate energy.

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Section: Introductionmentioning

confidence: 78%

RNA-Seq reveals a central role for lectin, C1q and von Willebrand factor A domains in the defensive glue of a terrestrial slug

et al. 2017

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“…The radius of the dishes, R, and the height, h, are between 36 mm and 150 mm and between 8 mm and 40 mm respectively. The shear modulus of the gel is measured by indentation of a non-adhesive rigid sphere (diameter 6 mm at the surface of control samples fully covered with pure water in order to remove capillary forces [14][15][16]. For the experiments reported here, it lies between 10 and 160 Pa, a low value compared to modulus of ordinary rubber-like materials (µ ∼ 1 MPa), but comparable with the modulus of tissues (as liver or brain).…”

Section: Methodsmentioning

confidence: 96%

The shape of hanging elastic cylinders

et al. 2019

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Deformations of heavy elastic cylinders with their axis in the direction of earth's gravity field are investigated. The specimens, made of polyacrylamide hydrogels, are attached from their top circular cross section to a rigid plate. An equilibrium configuration results from the interplay between gravity that tends to deform the cylinders downwards under their own weight, and elasticity that resists these distortions. The corresponding steady state exhibits fascinating shapes which are measured with lab-based micro-tomography. For any given initial radius to height ratio, the deformed cylinders are no longer axially symmetric beyond a critical value of a control parameter that depends on the volume force, the height and the elastic modulus: self-similar wrinkling hierarchies develop, and dimples appear at the bottom surface of the shallowest samples. We show that these patterns are the consequences of elastic instabilities.

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“…The corresponding indentation force F i is given by: where E is the Young’s modulus and ν is the Poisson’s ratio of the substrate. We employ equation (4) to fit the experimental data of the indentation part of the curves, by assuming ν = 0.5 for the gelatin (Czerner et al, 2015) and β = 5.5° for the viper fang and β = 8° for the burrowing snake fang, as shown in Figure A1. The deformed shape of the surface outside of the contact area (i.e., for x > a ) is given by (Sneddon, 1965): …”

Section: Resultsmentioning

confidence: 99%

Mechanics of snake biting: Experiments and modelling

Kundanati

Guarino

Menegon

et al. 2019

Preprint

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Among all the vertebrates, snakes possess the most sophisticated venom delivering system using their fangs. Fangs of many animals are well adapted to the mechanical loads experienced during the functions such as breaking the diet and puncturing the skin of the prey. Thus, investigation and modelling of puncturing mechanics of snakes is of importance to understand the form-function relationship of the fangs and tissue-fang interactions in detail. We have thus chosen fangs of two snake species i.e. viper (Bitis arietans) and burrowing snake (Atractaspis aterrima), with different shape and size and performed insertion experiments using tissue phantoms. Our results showed that both the species have similar mechanical properties but there was a difference in the insertion forces owing to the difference in shape of the fang. Also, our modelling of the fang-tissue interactions predicted some parameters close to the experimental values. Thus, our study can help in the development of bioinspired needles that can potentially have reduced insertion forces and less damage to the tissue.

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Determination of Elastic Modulus of Gelatin Gels by Indentation Experiments

Cited by 97 publications

References 5 publications

RNA-Seq reveals a central role for lectin, C1q and von Willebrand factor A domains in the defensive glue of a terrestrial slug

RNA-Seq reveals a central role for lectin, C1q and von Willebrand factor A domains in the defensive glue of a terrestrial slug

The shape of hanging elastic cylinders

Mechanics of snake biting: Experiments and modelling

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