Determination of Dopamine in the Presence of Uric Acid and Folic Acid by Carbon Paste Electrode Modified with CuO Nanoparticles/Hemoglobin and Multi-Walled Carbon Nanotube

Ghodsi, Javad; Rafati, Amir Abbas; Shoja, Yalda; Najafi, Mojgan

doi:10.1149/2.0491504jes

Cited by 32 publications

(18 citation statements)

References 44 publications

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“…Dopamine is a neurotransmitter that is an integral part of the central nervous system. It causes low-level neurological disorders like senile dementia, epilepsy, Parkinson's Huntington's schizophrenia, and Alzheimer's disease [58][59][60][61].…”

Section: Sensors For Dopamine Detectionmentioning

confidence: 99%

Copper Oxide Nanoparticles: Reactive Oxygen Species Generation and Biomedical Applications

Sarfraz¹,

Javed²,

Mughal³

et al. 2020

IJCTC

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Copper oxide is a p-type semiconductor which has many applications in a different field. Copper oxide has excellent applications as an antioxidant, antibacterial, and antitumor or anticancer. Copper oxide nanoparticle combines with the cell membrane and enters into a cell; generate reactive oxygen specie (ROS), which causes oxidative stress in the cell. Oxidative stress leads to metastasis, cancer proliferation, apoptosis, DNA damage, cytotoxicity, and unregulated cell signaling. Hydroxyl free radical generated by Nanoparticles, combined with DNA and yield 8-hydroxyl-2-deoxyguanosine (8-OHdG), resultantly DNA is damaged. CuO nanoparticle shows antibacterial activity on different bacterial strains such as staphylococcus aureus, bacillus circulens BP2, Escherichia coli, and P. aeruginosa. Recently, CuO nanoparticles have applications in the detection of Cholesterol, lactate biosensor, DNA sequencing of microbe, and anti-HIV drug analysis. There is specialized CuO nanoparticle such as Glucose sensor, Hydrogen peroxide sensor, Immunosensor, Dopamine sensor for the detection of the different biomolecule. ROS generated by CuO nanoparticle causes toxicity, which leads to cell death. There is a fascinating area of research against tumors by nanoparticle use because of its antitumor nature. Metal nanoparticle exhibits anticancer activity due to physicochemical properties as antioxidant action or use of external stimuli. Free radical which are produced by the metal nanoparticle, kill cancer cells.

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Section: Sensors For Dopamine Detectionmentioning

confidence: 99%

Copper Oxide Nanoparticles: Reactive Oxygen Species Generation and Biomedical Applications

Sarfraz¹,

Javed²,

Mughal³

et al. 2020

IJCTC

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“…Though analytical methods like chro matography, fluorescence, mass spectrometry and other techniques are available for the detection of Tyr [19][20][21][22], DA [23][24][25][26][27][28][29][30][31] and AA [32][33][34][35][36][37][38] in biological fluids, they are useful to certain extent due to their own limitations. Owing to fast response, accuracy and portability, the electrochemical methods using electrochemical sensors [39] to analy ze the DA, AA and Tyr coexisting in biological flu id [40][41][42][43] are very promising in accurate quantification of these bio-molecu les.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous detection of dopamine, tyrosine and ascorbic acid using NiO/graphene modified graphite electrode

2020

Biointerface Res Appl Chem

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In this work, an electrochemical sensor is fabricated by decorating the surface of graphite electrode with NiO/graphene (NGMG) nanoparticles and employed for the detection of dopamine (DA), tyrosine (Tyr) and ascorbic acid (AA). The structure and morphology of prepared NiO nanoparticles are examined by XRD,SEM, FTIR and Raman techniques. The electrochemical properties have been investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV) and chronoamperommety. The modified electrode is prepared by a simple drop casting method. The electrode shows good electro catalyticactivity towards oxidation of DA, Tyr and AA. It successfully separates the oxidation current signals of AA, DA and Tyr into clearly visible three distinct oxidation peaks compared to a single, overlapped oxidative peak on bare graphite electrode. The peak potential difference between AA-DA, DA-Tyr and AA-Tyr is 228 mV, 303 mV and 565 mV respectively in cyclic voltammetry (CV) studies and the corresponding peak potential separations are 243 mV, 318 mV and 561 mV respectively in differential pulse voltammetry (DPV). It is found that oxidation mechanism of DA, AA and Tyr on NGMG are different owing to a different type of interaction of the modified layer with the bio-analytes. The modified electrode, NGMG has high selectivity and sensitivity in addition to other factors like low cost, convenient and a hassle free electrochemical method for simultaneous determination of DA, AA and Tyr in their ternary mixture.

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“…It is necessary to design DA biosensor with excellent characteristics such as high sensitivity and excellent selectivity. Recently several analytical methods have been proposed for the DA detection such as high-performance liquid chromatography (HPLC) 12 , chemiluminescence 13 , fluorescence 14 , capillary electrophoresis 15 , mass spectrometry, calorimetry 16 , and surface-enhanced Raman scattering spectroscopy 17 . Although, these methods associated with some drawbacks such as require complicated pretreatment, time-consuming, expensive instruments, and consume large quantities of chemical, solvents, and reagents which might possibly cause environmental pollution 18,19 .…”

Section: Introductionmentioning

confidence: 99%

A core-shell molybdenum nanoparticles entrapped f-MWCNTs hybrid nanostructured material based non-enzymatic biosensor for electrochemical detection of dopamine neurotransmitter in biological samples

Keerthi

Boopathy

Chen

et al. 2019

Sci Rep

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Dopamine (DA) is a critical neurotransmitter and has been known to be liable for several neurological diseases. Hence, its sensitive and selective detection is essential for the early diagnosis of diseases related to abnormal levels of DA. In this study, we reported novel molybdenum nanoparticles self-supported functionalized multiwalled carbon nanotubes (Mo NPs@f-MWCNTs) based core-shell hybrid nanomaterial with an average diameter of 40–45 nm was found to be the best for electrochemical DA detection. The Mo NPs@f-MWCNTs hybrid material possesses tremendous superiority in the DA sensing is mainly due to the large surface area and numerous electroactive sites. The morphological and structural characteristics of the as-synthesized hybrid nanomaterial were examined by XRD, Raman, FE-SEM, HR-TEM, EDX. The electrochemical characteristics and catalytic behavior of the as-prepared Mo NPs@f-MWCNTs modified screen-printed carbon electrode for the determination of DA were systematically investigated via electrochemical impedance spectroscopy, cyclic voltammetry, and amperometry. The results demonstrate that the developed DA biosensor exhibit a low detection limit of 1.26 nM, excellent linear response of 0.01 µM to 1609 µM with good sensitivity of 4.925 µA µM−1 cm−2. We proposed outstanding appreciable stability sensor was expressed to the real-time detection of DA in the real sample analysis of rat brain, human blood serum, and DA hydrochloride injection.

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Determination of Dopamine in the Presence of Uric Acid and Folic Acid by Carbon Paste Electrode Modified with CuO Nanoparticles/Hemoglobin and Multi-Walled Carbon Nanotube

Cited by 32 publications

References 44 publications

Copper Oxide Nanoparticles: Reactive Oxygen Species Generation and Biomedical Applications

Copper Oxide Nanoparticles: Reactive Oxygen Species Generation and Biomedical Applications

Simultaneous detection of dopamine, tyrosine and ascorbic acid using NiO/graphene modified graphite electrode

A core-shell molybdenum nanoparticles entrapped f-MWCNTs hybrid nanostructured material based non-enzymatic biosensor for electrochemical detection of dopamine neurotransmitter in biological samples

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