Determination of Chlorpheniramine and Its Binding with Human Serum Albumin by Capillary Electrophoresis with Tris(2,2′-bipyridyl)ruthenium(II) Electrochemiluminescence Detection

Chemiluminescence determination of chlorpheniramine using tris(1,10‐phenanthroline)–ruthenium(II) peroxydisulphate system and sequential injection analysis

“…Gas chromatographic, HPLC, spectrophotometric, radioimmunoassay, capillary electrophoresis and CL methods have been applied to the analysis of this compound (36)(37)(38)(39)(40)(41)(42)(43)(44)(45)]. Recently, an LC-MS-MS method, using 2-acetamidophenol as an internal standard, was reported for the determination of CPA (46).…”

“…4(N,Ndimethylaminosulphonyl)-7-fluoro-2,1,3-benzoxadiazole and bis(2,4,6-trichlorophenyl)-oxalate-hydrogen peroxide were used as post-column CL reagents for CPA following its derivatization with dansyl chloride (40,41). Other CL methods are also reported where the luminol-potassium ferricyanide system and electrochemically generated Ru(bpy) 3 3+ were used as post-column reagents (42,43).…”

Functionalized Fe3O4Magnetic Nanoparticle Potentiometric Detection Strategy versus Classical Potentiometric Strategy for Determination of Chlorpheniramine Maleate and Pseudoephedrine HCl

“…A detailed survey for the reported methods that were utilized for the analysis of CPM, PSE, and IBF has revealed that these drugs were determined either singly or in their binary mixtures by spectrophotometry [4, 5], HPTLC [6], HPLC-MS and GC-MS [7–9], HPLC-UV [10], capillary electrophoresis [11, 12], and potentiometry [13–22]. However, only one method was found for the simultaneous determination of the three drugs based on liquid chromatography with experimental design [23].…”

A solid-state electrochemiluminescence composite modified electrode based on Ru(bpy)32+/PAHNSA: Characterization and pharmaceutical applications

“…Chlorpheniramine maleate (CPM), a common antihistamine drug used regularly for cold and cough treatment, has been quantified in pharmaceutical formulations and biological fluids using different methods. These include spectrophotometry [26], liquid chromatography [27], mass spectrometry [28], electrochemical [29][30][31], CL [32] and ECL [33][34].…”