Determination of Bioactive Components of Myxopyrum Serratulum A.W. Hill (Oleaceae) Stem by Gc-MS Analysis

Abstract

The present study is to evaluate bioactive compounds of ethanol extract of Myxopyrum serratulum stem using GC-MS analysis. The chemical compositions of the ethanol extract of stem of Myxopyrum serratulum were investigated using Perkin-Elmer Gas Chromatography-Mass Spectrometry, while the mass spectra of the compounds found in the extract were matched with the National Institute of Standard and Technology (NIST) library. Thirty two compounds were identified. The prevailing compounds in ethanol extract were 2-Propenoic acid, 3-(4-methoxyphenyl)-, α-Amyrin, 1-(2-Hydroxy-ethyl)-2-methyl-1H-benzoimidazole-5-carboxylic acid methyl ester, n-Hexadecanoic acid, Pyrazolidine-3,5-dione and 4-phenyl-, 5-Hydroxymethylfurfural. The compounds identified through the GC-MS analysis were used in various applications as antimicrobial, antiinflammatory, hepatoprotective and cancer preventive.

Mystroxylon aethiopicum chloroform root bark extracts phytochemical analysis using gas chromatography mass spectrometry

“…Additionally, fatty acids identified are 9,12,15-octadecatrienoic acid, (Z,Z,Z), 9,12-octadecadienoic acid (Z,Z), 9-octadecenoic acid, (E), tetradecanoic acid and nhexadecanoic acid (Figure 2). α-humulene, isoledene, caryophyllene oxide, 9,12,15-octadecatrienoic acid (Z,Z,Z), 9,12-octadecadienoic acid (Z,Z), 9-octadecenoic acid (E), tetradecanoic acid and nhexadecanoic acid (Kumar et al, 2010;Prabhadevi et al, 2012;Sermakkani and Thangapandian, 2012;Rajeswari et al, 2011;Devi and Muthu, 2014;Selvamangai and Bhaskar, 2012;Prabhadevi et al, 2012;Mickymaray et al, 2015;Hadri et al, 2010;Legault and Pichette, 2007;Sagwan et al, 2013;Kajalakshmi and Mohan, 2016;Asif et al, 2016).…”

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“…L-(+)-Ascorbic acid 2,6-dihexadecanoate exhibit antinociceptive, anti-inflammatory and anti-oxidant properties 54,55 . 3, 7, 11, 15-Tetramethyl-2hexadecen-1-ol have several biological activities like anti-inflammatory and antimicrobial 56 . Nhexadecanoic acid also known as Palmitic acid possesses 5-alpha reductase inhibitor activities antiandrogenic, antioxidant, hypocholesterolemic, lubricant, hemolytic, flavor, nematicide, pesticide and mosquito larvicide 55,56 .…”

“…The 9,12-Octadecadienoic acid (Z,Z)-(Linoleic acid) obtained from the methanol extract exhibit more biological activities like anti-acne, antiandrogenic, anti-arthritic, anti-coronary, antieczemic, anti-histamine, anti-inflammatory, cancer preventive, hepatoprotective, hypercholesterolemic, insectifuge, nematicide, and 5-alpha reductase inhibitor 56 . The bioactive compounds present in Xylosma longifolia have various pharmacological and therapeutic activities.…”

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“…Beta-D-glucopyranose, 1, 6-anhydro also known as Levoglucosan acts as a preliminary material for the synthesis of stereoregular polysaccharides and have anti-human immunodeficiency virus and blood coagulant activities 18 . L-gala-L-ido-octose is an important compound needed for memory drug production 19 20,21 . The 9, 12-Octadecadienoic acid (Z, Z)-(Linoleic acid) obtained from GC-MS analysis has many biological activities like anti-acne, anti-androgenic, anti-arthritic, anti-coronary, anti-eczemic, anti-histamine, anti-inflammatory, cancer preventive, 5alpha reductase inhibitor, hepatoprotective, hypercholesterolemic, insectifuge and nematicide 20 .…”

“…L-gala-L-ido-octose is an important compound needed for memory drug production 19 20,21 . The 9, 12-Octadecadienoic acid (Z, Z)-(Linoleic acid) obtained from GC-MS analysis has many biological activities like anti-acne, anti-androgenic, anti-arthritic, anti-coronary, anti-eczemic, anti-histamine, anti-inflammatory, cancer preventive, 5alpha reductase inhibitor, hepatoprotective, hypercholesterolemic, insectifuge and nematicide 20 . Oleyl alcohol (cis-9-octadecen-1-ol) and 9, 12-Octadecadienoic acid, methyl ester (Methyl linoleate) were the major compounds obtained in the study have the anti-tumor or anti-cancer properties 22,23 .…”