Determination of azoxystrobin and its impurity in pesticide formulations by liquid chromatography

Identification and Characterization of the Isomeric Impurity of the Fungicide “Cyazofamid”

“…In recent times, researchers have been focusing on the impurity profiling of agrochemicals. [7][8][9][10][11][12][13] In these lines, we have developed high-performance liquid chromatography (HPLC), gas chromatography/mass spectrometry, and nuclear magnetic resonance (NMR)-based analytical methods for investigating the impurity profile of bifenthrin. [2] Cyazofamid, chemically known as 4-chloro-2-cyano-N,Ndimethyl-5-p-tolylimidazole-1-sulfonamide (Scheme 1), is a fungicide belonging to the phenylimidazole family that has broad spectrum activity against plasmodiophoromycetes and oomy-cetes with various sites of action.…”

A novel validated simple derivatization liquid chromatographic method with diode array detection for the simultaneous determination of mancozeb, azoxystrobin and difenoconazole in pesticide dosage form

“…For the determination of mancozeb by iodometry, 12 square-wave adsorptive stripping voltammetry (SWAdSV), 13,14 batch injection analysis (BIA) with pulsed amperometric detection (PAD) on boron-doped diamond (BDD) electrode, 15 UV-spectrophotometry, 16–20 flow injection (FI) spectrophotometry, 21,22 photoacoustic and Fourier transform infrared spectroscopy, 23,24 gas chromatography (GLC) with specific detectors such as an electron capture detector (ECD), flame atomic absorption spectroscopic detector (FAAS) and flame photometric detector (FPD), 25,26 high performance liquid chromatography (HPLC), 27–35 gas chromatography-mass spectrometry (GC-MS), 36–42 and liquid chromatography-mass spectrometry (LC-MS) 43–49 methods have been reported. Similarly, various analytical methods for the quantification of azoxystrobin using UV-spectrophotometry, 50 flow injection chemiluminescence (FI-CL), 51 gas chromatography (GLC), 52–58 high-performance liquid chromatography (HPLC), 59–68 gas chromatography-mass spectrometry (GC-MS) 69–71 and liquid chromatography-mass spectrometry (LC-MS) 72–74 for single and multipesticide formulations were reported in literature. Furthermore, several methods for the quantification of Difenoconazole using voltammetric and flow amperometric detection on a boron-doped diamond electrode (FIA-ED), 75 UV-spectrophotometry, 76 gas chromatography (GLC), 77–83 high-performance liquid chromatography(HPLC), 84–87 gas chromatography-mass spectrometry (GC-MS) 88–92 and liquid chromatography-mass spectrometry (LC-MS) 93–99 methods were repored.…”

Development and validation of stability-indicating RP-HPLC method for the estimation of azoxystrobin in its formulations

“…The approach has been shown to be effective for extracting and determining Azoxystrobin residues in green beans and peas based on these findings. P.Marczewska et al 3 used high performance liquid chromatography with diode array detector (HPLC-DAD) in suspension concentrate pesticide formulations to create a technique for the simultaneous qualitative and quantitative measurement of Azoxystrobin and its related impurity (Z)azoxystrobin. Individual recovery rates for azoxystrobin and (Z)-azoxystrobin were 97-103 % and 90-110 %, respectively.…”