Determination of Artesunate by Capillary Electrophoresis with Low UV Detection and Possible Applications to Analogues

D’Hulst, A.; Augustijns, Patrick; Arens, S.; Parijs, L. Van; Colson, Sylvia H.; Verbeke, Norbert; Kinget, Renaat

doi:10.1093/chromsci/34.6.276

Cited by 15 publications

(7 citation statements)

References 16 publications

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“…Densitometric scanning was performed on Camag TLC scanner III in the reflectance mode at 565 nm [13] and operated by winCATS Planar chromatography version 1.1.3.0. The source of radiation utilized was halogen tungsten lamp.…”

Section: Hptlc Instrumentationmentioning

confidence: 99%

“…These methods include gas chromatography-mass spectrometry (GC-MS) [6], high-performance liquid chromatography (HPLC) based on UV absorption [7][8][9], chemiluminescence and electrochemical detection [10], high-performance thin-layer chromatography (HPTLC) [11,12] and the capillary electrophoresis techniques [13]. Recently, Gabriëls and Plaizier-Vercammen have reported determination of artemether by using normal phase thin-layer chromatography (NPTLC) [11] using pure chloroform as the mobile phase and also the use of reverse phase thin-layer chromatography (RPTLC) [12] using acetonitrile-water as mobile phase.…”

Section: Introductionmentioning

confidence: 99%

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Validated HPTLC method of analysis for artemether and its formulations

Tayade

Nagarsenker

2007

Journal of Pharmaceutical and Biomedical Analysis

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Section: Hptlc Instrumentationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Validated HPTLC method of analysis for artemether and its formulations

Tayade

Nagarsenker

2007

Journal of Pharmaceutical and Biomedical Analysis

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“…Only limited methods have been reported in the literature survey [ 4 – 10 ]. The aim of the present work was to develop and validate a simple, fast, and reliable isocratic RP-HPLC and UV method for the determination of DI in pharmaceutical dosage forms.…”

Section: Introductionmentioning

confidence: 99%

Development and Validation of a HPLC and an UV Spectrophotometric Methods for Determination of Dexibuprofen in Pharmaceutical Preparations

Muralidharan

Meyyanathan

2011

ISRN Pharmaceutics

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A high-performance liquid chromatographic (HPLC) and a ultraviolet (UV) methods were developed and validated for the quantitative determination of Dexibuprofen (DI) in pharmaceutical dosage form. HPLC was carried out by reversed phase technique on a RP-18 column with a mobile phase composed of acetonitrile and 0.5% triethylamine (pH 7.5 adjusted with orthophosphoric acid (30 : 70, v/v)). UV method was performed with the λ max at 222.0 nm. Both the methods showed good linearity, reproducibility and precision. No spectral or chromatographic interferences from the tablet excipients were found in UV and HPLC. The method was successfully applied to commercial DEXIFEN tablets. Validation parameters such as linearity, precision, accuracy, and specificity were determined. The proposed method could be applicable for routine analysis of DI and monitoring of the quality of marketed drugs.

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“…outros métodos aplicados no estudo para quantificação da artemisinina foram cromatografia líquida capilar, cromatografia com fluido supercrítico, 20 cromatografia em camada delgada, 21 voltametria cíclica 22 e eletroforese capilar. 23 A maioria dos artigos contempla análises apenas com padrões e as referências que descrevem a utilização de extratos não levaram em consideração o número de etapas envolvidas no processo de limpeza e a recuperação do analito durante as extrações.…”

Section: Introductionunclassified