Determination of arsenic species in Solanum Lyratum Thunb using capillary electrophoresis with inductively coupled plasma mass spectrometry

Abstract

A simple and highly efficient interface to couple capillary electrophoresis with inductively coupled plasma mass spectrometry by a microflow polyfluoroalkoxy nebulizer and a quadruple ion deflector was developed in this study. By using this interface, six arsenic species, including arsenite, arsenate, monomethylarsonic acid, dimethylarsinic acid, arsenobetaine, and arsenocholine, were baseline-separated and determined in a single run within 11 min under the optimized separation conditions. The instrumental detection limit was in the range of 0.02-0.06 ng/mL for the six arsenic compounds. Repeatability expressed as the relative standard deviation (n = 5) of both migration time and peak area were better than 2.5 and 4.3% for six arsenic compounds. The proposed method, combined with a closed-vessel microwave-assisted extraction procedure, was successfully applied for the determination of arsenic species in the Solanum Lyratum Thunb samples from Anhui province in China with the relative standard deviations (n = 5) ≤4%, method detection limits of 0.2-0.6 ng As/g and a recovery of 98-104%. The experimental results showed that arsenobetaine was the main speciation of arsenic in the Solanum Lyratum Thunb samples from different provinces in China, with a concentration of 0.42-1.30 μg/g.

Determination of different arsenic species in food‐grade spirulina powder by ion chromatography combined with inductively coupled plasma mass spectrometry

“…The effects of other MAE parameters on the extraction of As species were further investigated, similar to our previous report [13]. The experimental results also revealed that the ratio of extracting solvent volume to spirulina powder mass of 300 mL/g is the best ratio (Fig.…”

“…Their RSDs (n = 5) of migration time and peak area were 0.2-1.3% and 0.8-4.8%, respectively. Their instrumental detection limit (3σ/S) calculated with counts was 5.00, 5.00, 10.0, and 10.0 ng/L, respectively, much lower than that obtained in CE-ICP-MS [13,18].…”

“…Method detection limit for As species in spirulina samples was also investigated based on the results of IC-ICP-MS (Supporting Information Table S2). The method detection limit of As(III), DMA(V), MMA(V), and As(V) in spirulina samples was 0.1, 0.1, 0.2, and 0.2 ng/g, respectively, two to three times lower than that obtained in CE-ICP-MS even if the highly sensitive polyfluoroalkoxy nebulizer was used for nebulization [13].…”

“…So far, various method have been developed for extracting different arsenic compounds in different samples [11], and it is accepted that MAE is a more effective method for extracting As species from alga products than shaking or sonication extraction [12]. Moreover, the extraction efficiency of MAE is also closely related to its parameters such as the composition of extracting solvents, ratios of extracting solvents volume to sample mass, microwave heating temperature, and time [13].…”

Simultaneous detection of zinc dimethyldithiocarbamate and zinc ethylenebisdithiocarbamate in cabbage leaves by capillary electrophoresis with inductively coupled plasma mass spectrometry

“…Inductively coupled plasma mass spectrometry (ICP‐MS), which is widely used for the determination of trace metals , possesses several inherent advantages including extremely high sensitivity for most metallic ions, wide linear dynamic range, high speed analysis, excellent mass resolution for metallic ions, and the ability to perform isotopic analysis . Therefore, the coupling of CE and ICP‐MS becomes a powerful tool for elemental speciation analysis, and has been used in the speciation analysis of some elements such as arsenic , selenium , lead , mercury , and chromium . To the best of our knowledge, the method of simultaneous analysis of Ziram and Zineb using CE–ICP‐MS has not been reported so far.…”