Determination of Antimicrobial Agents in Non-Formalin Adhesives for Wallpaper.

Nakashima, Harunobu; Matsunaga, Ichiro; Miyano, Naoko; Kitagawa, Mikiya

doi:10.1248/jhs.46.447

Cited by 28 publications

(19 citation statements)

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“…Furthermore, Cl-MIT was only detected in samples that contained MIT and the concentrations of Cl-MIT detected in the samples were two or three times higher than those of MIT, except for in A17 and B6. A similar tendency was also observed in wallpaper adhesives 15) . It was thought that the reason for this tendency was that the preservatives always contained Cl-MIT as a mixture with MIT (for example, Kathon TM CG 6) ) and the concentration of Cl-MIT was three or four times higher than MIT in these preservatives.…”

Section: Concentrations and Detection Frequencies Of The Target Composupporting

confidence: 82%

Analysis of Isothiazolinones and Other Preservatives in Gel-Products Used for Cooling in Japan

2012

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Summar yRecently, two cases of contact dermatitis caused by 2-n-octyl-4-isothiazolin-3-one (OIT) used as a preservative in cooling gel-products has been reported in Japan, and one of the cases was declared a serious product accident based on the ＂Consumer Safety Product Act.＂ In this study, the concentrations of three isothiazolinone preservatives (OIT, 2-methyl-4-isothiazolin-3-one [MIT], and 5-chloro-2-methyl-4-isothiazolin-3-one [Cl-MIT]), seven different parabens, carbendazim (MBC), and tebuconazole (Teb) in 24 cooling gel-products were investigated. OIT was detected in two samples (0． 14 µg/g and 2． 2 µg/g). MIT was detected in 11 samples at concentrations in the range of 0． 12-115 µg/g and Cl-MIT was detected in six samples in concentrations ranging from a trace amount to 16 µg/g. The EU cosmetic limits were used to consider the risk of skin sensitization and the concentrations of MIT and Cl-MIT detected in several samples were over these limit. It is possible for the gel to cause contact dermatitis when the consumer＇s weight presses on the gel-product because OIT might penetrate from the gel to the textile surface in the case of a serious product accident. Furthermore, it is possible that using the gel product for the forehead or neck has a similar risk of skin sensitization if the gel-product＇s surface tears and the gel containing isothiazolinone preservative leaks out. It is advisable to replace the preservatives in cooling gel-products with non-sensitizing preservatives. All parabens were detected in the gel-products, except benzylparaben, and their concentrations were 12-696 µg/g. MBC and Teb were detected in three samples with concentrations in the ranges of 0． 82-54 µg/g and 1． 5-25 µg/g, respectively.

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Section: Concentrations and Detection Frequencies Of The Target Composupporting

confidence: 82%

Analysis of Isothiazolinones and Other Preservatives in Gel-Products Used for Cooling in Japan

2012

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“…Actually, many recent developments in LLE have been focused on new techniques, which greatly reduce the amount of solvent used (cost and environmental factors) and facilitate automation of the process in conjunction with chromatographic analysis [84]. In the literature, a number of reports describe the use of LLE during sample preparation of different samples prior to the evaluation of their isothiazolinone content [83,85,86].…”

Section: Analysis and Determination Of Isothiazolinone Biocidesmentioning

confidence: 99%

“…The wide variety of cartridge types and solvents makes the SPE procedure suitable for many polar or nonpolar analytes. For the analysis of isothiazolinones, different SPE stationary phases were used [83,[86][87][88][89][90][91].…”

Section: Analysis and Determination Of Isothiazolinone Biocidesmentioning

confidence: 99%

Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles

et al. 2020

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The importance of isothiazole and of compounds containing the isothiazole nucleus has been growing over the last few years. Isothiazolinones are used in cosmetic and as chemical additives for occupational and industrial usage due to their bacteriostatic and fungiostatic activity. Despite their effectiveness as biocides, isothiazolinones are strong sensitizers, producing skin irritations and allergies and may pose ecotoxicological hazards. Therefore, their use is restricted by EU legislation. Considering the relevance and importance of isothiazolinone biocides, the present review describes the state-of-the-art knowledge regarding their synthesis, antibacterial components, toxicity (including structure–activity–toxicity relationships) outlines, and (photo)chemical stability. Due to the increasing prevalence and impact of isothiazolinones in consumer’s health, analytical methods for the identification and determination of this type of biocides were also discussed.

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“…The most common antimicrobial compounds are benzalkonium chloride, triclosan and silver [4-6] although other heavy metals are also used. Some antimicrobials incorporated to other materials have been applied as adhesives [7], window cleaners [8], textiles, and wallpaper gloves [9], among others.…”

Section: Introductionmentioning

confidence: 99%

Gold nanoparticles as efficient antimicrobial agents for Escherichia coli and Salmonella typhi

Lima¹,

Guerra-González

Lara

et al. 2013

Chemistry Central Journal

169

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BackgroundIt is imperative to eliminate bacteria present in water in order to avoid problems in healthy. Escherichia coli and Salmonella typhi bacteria are two common pollutants and they are developing resistance to some of the most used bactericide. Therefore new biocide materials are being tested. Thus, gold nanoparticles are proposed to inhibit the growth of these two microorganisms.ResultsGold nanoparticles were supported onto clinoptilolite, mordenite and faujasite zeolites. Content of gold in materials varied between 2.3 and 2.8 wt%. The size, dispersion and roughness of gold nanoparticles were highly dependent of the zeolite support. The faujasite support was the support where the 5 nm nanoparticles were highly dispersed. The efficiency of gold-zeolites as bactericides of Escherichia coli and Salmonella typhi was determined by the zeolite support.ConclusionsGold nanoparticles dispersed on zeolites eliminate Escherichia coli and Salmonella typhi at short times. The biocidal properties of gold nanoparticles are influenced by the type of support which, indeed, drives key parameters as the size and roughness of nanoparticles. The more actives materials were pointed out Au-faujasite. These materials contained particles sized 5 nm at surface and eliminate 90–95% of Escherichia coli and Salmonella typhi colonies.

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Determination of Antimicrobial Agents in Non-Formalin Adhesives for Wallpaper.

Cited by 28 publications

References 1 publication

Analysis of Isothiazolinones and Other Preservatives in Gel-Products Used for Cooling in Japan

Analysis of Isothiazolinones and Other Preservatives in Gel-Products Used for Cooling in Japan

Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles

Gold nanoparticles as efficient antimicrobial agents for Escherichia coli and Salmonella typhi

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