Determination of a dantrolene metabolite, 5-(p-nitrophenyl)-2-furoic acid, in plasma and urine by high-performance liquid chromatography

Analytical Aspects of Amino, Quaternary Ammonium, Nitro, Nitroso and Related Functional Groups

“…A sensitive HPLC method for the determination of 5-(4-nitrophenyl)-2-furoic acid (225), a dantrolene (226) metabolite, in blood plasma and urine was developed 464 .…”

Stability-Indicating Chromatographic Methods for the Determination of a Skeletal Muscle Relaxant and an Analgesic in their Combined Dosage Form

“…Literature review revealed that several electrochemical methods [4][5][6] and HPLC methods [7][8][9][10][11][12][13][14] have been reported for the determination of DNT either in pharmaceutical or biological samples. Degradation behavior of DNT was reported in different buffers and temperature [15].…”