Determination of 5-methoxypsoralen in human serum

Simultaneous and sensitive determination of xanthotoxin, psoralen, isoimpinellin and bergapten in rat plasma by liquid chromatography–electrospray ionization mass spectrometry

“…A number of analytical methods have been developed to determine the four compounds in plasma, urine and serum including fluorometric method [17], high-performance liquid chromatography with ultraviolet detection (HPLC-UV) [18][19][20] or fluorometric detection (HPLC-FD) [21], thin layer chromatogra- Fig. 1.…”

Implementation of a Spectrofluorimetric Method to the Determination of 8-Methoxypsoralen in Capsules and Creams Used in Treatment of Psoriasis and Vitiligo: an Evaluation of the Quality of Compounding Pharmacies in Rio de Janeiro

“…A spectrofluorimetric determination was chosen for quantification of 8-MOP in the manipulated formulations due to the knowledge about the intrinsic fluorescence characteristics of the molecule. 17 This is a low-cost and simple technique when compared to the chromatographic methods described in the literature for 8-MOP and its isomer 5-methoxypsoralen (5-MOP), [18][19][20][21] becoming more appealing for compounding pharmacies. Said et al 22 published a paper describing a spectrofluorimetric method to another psoralen (5-methoxypsoralen) in serum samples of patients, but did not show results for 8-MOP.…”

A method for fast determination of psoralens in oral solutions of phytomedicines using liquid chromatography

“…HPLC methods have been reported for the determination of psoralens in callus cultures, vitro culture, serum, dermis, plants, citrus essential oils, phytomedicines, but only the most recent published methods report assay validation [8,[18][19][20][21][22][23][24][25][26]. There are no previous descriptions in the literature about sample preparation and HPLC analysis of psoralen and bergapten (Fig.…”