Determinants of Survival of Cervical Cancer: A Hospital Based Study

Abstract

Globally uterine cervix cancer is one of the leading causes of death in females due to cancer, especially in developing countries. The aim of the study was to analyse the survival as well as understanding various prognostic factors for survival in patients of carcinoma cervix presenting in our hospital. A total of 508 patients were evaluated in radiotherapy department of Mahavir Cancer Sansthan and Research centre Patna, Bihar who came for follow up between April 2015 to March 2016 after completion of radical radiotherapy. Out of 508 patients 3.54% (n 18), 71.65% (n 364), 22.83% (n 116) and 1.9% (n 10) patients presented in sage I, II, III and IV A respectively. 53.54% of patients belonged to age group of 35 to 50 years with Survival of 937 ± 53.49 days. 46.46% of the patients were more than 50 years age and their survival was 933.3 ± 57.12 days. The mean duration for overall survival for all cases evaluated was 957.4 ± 39.49 days. The mean duration for survival of stages I, II, III and IVA was 1186 ± 281.8 days, 960 ± 85.04 days, 945.1 ± 45.66 days and 765 ± 181.5 days respectively. Survival of patients having squamous cell carcinoma was 970 ± 42.89 days and that of adenocarcinoma was 669.5 ± 120 days and that of premenopausal and postmenopausal lady was 997.5 ± 79.28 and 940.1 ± 45.39 days respectively. It was evident from study that patients who presented in early stage had a better survival. There was no significant difference in survival of cervix cancer patients in different age groups while survival was greater in premenopausal cervical cancer patients.

Staging and Management of Cervical Cancer at the Colposcopy Clinic of Bangabandhu Sheikh Sheikh Mujib Medical University (BSMMU), Bangladesh

“…A study in Karnataka, India (stage I—7.36%, stage IIA—9.21%) and North East India (stage I—4.10%) revealed relatively smaller proportion of CC cases with early disease and this was related to lack of awareness and absence of efficient screening program in the mentioned parts of India during the mentioned period. 8 26 27 On the other hand, comparatively higher proportion of patients presented with stage I disease in rural Kerala (12.80%) and Trivandrum (11.10%), where state is running national CC screening program. 28 29 These studies stressed on the importance of formulating public health policies with improving awareness and implementation of CC screening programs.…”

Associated predictor covariates of cervical cancer stage and impact on survival at Khartoum oncology hospital, Sudan

“…1 In Sub-Saharan Africa, the incidence is low but mortality rates are high due to advanced stage at presentation. 5 In Sudan, cervical cancer represents more than 16% of all cancer in women and 85% of cases are diagnosed at an advanced stage. 6,7 Cervical cancer is closely related to human papillomavirus (HPV) 16/18 infection and 78% of cases in the Sudan are diagnosed as invasive Lesions.…”

Associated predictor covariates of cervical cancer and impact on survival at Khartoum oncology hospital, Sudan

“…In Africa, there is a wide variation due to different exposure and disease susceptibility 1 . In Sub-Saharan Africa, the incidence is low but mortality rates are high due to advanced stage at presentation 5 . In the Sudan, cervical cancer represents more than 16% of all cancer in women and 85% of cases are diagnosed at an advanced stage 6 , 7 .…”