Determinants of quality of life in advanced kidney disease: time to screen?

Iyasere, Osasuyi; Brown, Edwina A.

doi:10.1136/postgradmedj-2013-132251

Cited by 25 publications

(21 citation statements)

References 79 publications

(67 reference statements)

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“…This can however lead to important problems going unrecognised, such as pain and fatigue, which have a major impact on HRQOL. 4 Patient self-assessments should be included with laboratory metrics when assessing treatment outcomes.…”

Section: Introductionmentioning

confidence: 99%

Collection and determinants of patient reported outcome measures in haemodialysis patients in Scotland

Nimmo

Bell

Brunton

et al. 2017

QJM: An International Journal of Medicine

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Collection and determinants of patient reported outcome measures in haemodialysis patients in ScotlandNimmo, A.; Bell, S.; Brunton, C.; Campbell, J.; Doyle, A.; Mackinnon, B.; Peel, R. K.; Robertson, S.; Shilliday, I.; Spalding, E.; Traynor, J. P.; Metcalfe, W.; On behalf of the Scottish Renal Registry General rights Copyright and moral rights for the publications made accessible in Discovery Research Portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.• Users may download and print one copy of any publication from Discovery Research Portal for the purpose of private study or research.• You may not further distribute the material or use it for any profit-making activity or commercial gain.• You may freely distribute the URL identifying the publication in the public portal. There were significant differences in PROMs with age, SIMD quintile and primary renal diagnosis. Achieving a urea reduction ratio of >65% and dialysing through arteriovenous access were associated with significantly higher PROMs. PROMs were not affected by haemoglobin or phosphate concentration. Conclusions:Routine collection of PROMs is feasible and can identify potentially under-recognised and treatable determinants to quality of life. The association between attaining recommended standards of care and improved PROMs is striking. Individual and population-wide strategies are required to improve PROMs.

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Section: Introductionmentioning

confidence: 99%

Collection and determinants of patient reported outcome measures in haemodialysis patients in Scotland

Nimmo

Bell

Brunton

et al. 2017

QJM: An International Journal of Medicine

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“…It is evidenced that depression was prevalent and QoL was lower among CKD patients [12,13,14,15,16]. Several studies linked depression or low QoL to increased mortality risk in CKD patients [17,18,19], indicating the importance and potential effects of depression and QoL during CKD.…”

Section: Introductionmentioning

confidence: 99%

Depression and Quality of Life in Relation to Decreased Glomerular Filtration Rate Among Adults with Hypertension in Rural Northeast China

Guo

Zhao

et al. 2015

Kidney Blood Press Res

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Background/Aims: We aim to investigate the extent to which depression and quality of life might be associated with decreased glomerular filtration rate (GFR) in a large hypertensive population in rural Northeast China. Methods: A total of 5566 hypertensive participants aged 35 years and older were screened with a stratified cluster multistage sampling scheme in rural areas of Liaoning Province during 2012-2013. Decreased GFR was defined as estimated GFR <60 ml/min/1.73 m². Results: The overall prevalence of decreased GFR was 3.2%. In the multivariable regression model, participants with moderate or greater depression had a greater risk for having a decreased GFR (OR: 1.739, 95%CI: 1.004 to 3.014) after full adjustment. Every 1-point increase of all the domains in WHOQOL-BREF, except for physical and environment domains, was significantly related to a lower risk for decreased GFR adjusting for age, gender and race. However, after fully adjustment, only social relations remained significant (OR: 0.899, 95%CI: 0.820 to 0.985). Increasing in total scores of WHOQOL-BREF was a protective factor against decreased GFR after fully adjustment. Conclusion: We found that moderate or greater depression and lower quality of life were associated with higher risks for developing decreased GFR.

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“…The consequences of malnutrition include reduced quality of life, sleep disorder, depression, erythropoietin hyporesponsiveness, increased susceptibility to infections and aggravation of heart failure. [39][40][41][42] There is therefore, justification to incorporate nutritional assessment as part of managing CKD patients even in early stages as this study showed that malnutrition starts early in the course of CKD.…”

mentioning

confidence: 99%

Malnutrition in pre-dialysis chronic kidney disease patients in a teaching hospital in Southern Nigeria

Adejumo¹,

Enajite²

2016

Afr H. Sci.

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Background: Malnutrition is a complication in chronic kidney disease (CKD) known to affect quality of life and prognosis although not often diagnosed. It is associated with rapid progression to end stage renal disease (ESRD) and mortality. Early identification and treatment will slow down progression to ESRD and mortality. Objective: To determine the prevalence and pattern of malnutrition in pre-dialysis CKD patients in Southern Nigeria. Methods: One hundred and twenty consecutive pre-dialysis CKD and 40 control subjects without CKD were studied. Data obtained from participants were demographics, body mass index (BMI), and aetiology of CKD. Indices used to assess presence of malnutrition were low BMI, hypocholesterolaemia and hypoalbuminaemia. Statistical significance was taken at 0.05 level. Results: The mean age of the CKD subjects was 48.8±16.6years with a male: female ratio of 1.7:1. Prevalence of malnutrition in the CKD subjects was 46.7%, higher than 27.5% observed in the controls (p=0.033). Prevalence of malnutrition increased significantly across CKD stages 2 to 5 (p=0.020). It was significantly commoner in elderly patients (p=0.047) but not significantly different between males and females(p=0.188). Conclusion: Malnutrition is common in pre-dialysis CKD patients even in early CKD stages. Prevalence of malnutrition increases with worsening kidney function and increasing age.

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Determinants of quality of life in advanced kidney disease: time to screen?

Cited by 25 publications

References 79 publications

Collection and determinants of patient reported outcome measures in haemodialysis patients in Scotland

Collection and determinants of patient reported outcome measures in haemodialysis patients in Scotland

Depression and Quality of Life in Relation to Decreased Glomerular Filtration Rate Among Adults with Hypertension in Rural Northeast China

Malnutrition in pre-dialysis chronic kidney disease patients in a teaching hospital in Southern Nigeria

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