Determinants of medication adherence and blood pressure control among hypertensive patients in Hong Kong: A cross-sectional study

Kang, Candy D.; Tsang, Prilla P.M.; Li, Winson T.L.; Wang, Haoxiang; Liu, Kirin Q.L.; Griffiths, Siân; Wong, Martin C. S.

doi:10.1016/j.ijcard.2014.12.064

Cited by 84 publications

(95 citation statements)

References 24 publications

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“…The finding is similar with those of other studies in comprehensive teaching Hospital in Shanghai, China [32], Hong Kong [25], and Singapore [28]. When patients take antihypertensive medications for a long period, they would develop awareness about the complications of missing drugs and have good attitude about hypertension treatment, and these encourage patients to adhere.…”

Section: Discussionsupporting

confidence: 88%

“…This finding is supported by studies conducted in Adama Hospital [17], Gondar University Hospital [20], Bangladesh [31] and Hong Kong [25]. The adherence to antihypertensive medication was increased when there was no co- morbidity.…”

Section: Discussionsupporting

confidence: 65%

“…However, the finding is higher than what was reported in the study done in Adama Referral Hospital (59.5%) [17], Dar es Salaam (56%) [22], Eastern Nigeria (52.5%) [23], Southwest Nigeria (51%) [24], and Hong Kong (55.1%) [25]. This might be due to differences in socio-demographic characteristics, small sample size in Dar es Salaam and time difference.…”

Section: Discussionmentioning

confidence: 57%

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Drug adherence for antihypertensive medications and its determinants among adult hypertensive patients attending in chronic clinics of referral hospitals in Northwest Ethiopia

Mekonnen

Gebrie

Eyasu

et al. 2017

BMC Pharmacol Toxicol

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BackgroundAdherence to prescribed medication is an imperative issue which can be directly linked with the management of chronic diseases like hypertension; failure to adhere can affect the effectiveness of medication as well as the efficiency of the health care system. There is scarcity of information regarding the level of drug adherence for antihypertensive medications and its determinants in Ethiopia, particularly in the study area. Therefore, the aim of this study was to assess adherence level and its determinants for antihypertensive medications among adult hypertensive patients attending the chronic illness clinics of the referral hospitals in northwest Ethiopia.MethodsInstitution based cross sectional study was conducted from March to April, 2016. The systematic random sampling technique was used to select 409 study participants from three referral hospitals. The questionnaire was prepared using the World Health Organization (WHO) conceptual model and by reviewing international literature. The data were collected using an interviewer administered questionnaire. The data were entered in to Epi - Info version 7 and then transferred to the statistical package for social science (SPSS) version 20 for data cleaning and analysis.Bivariate analysis was first done to see the association between each independent variables and dependent variable. Variables with a P-value of less than 0.2 in the bivariate analysis were entered in to the multivariate logistic regression model for final analysis. Multivariate analysis was done using Backward logistic regression method. P-value less than 0.05 was considered to determine the statistical significance of the association and odds ratio with a 95% confidence interval was used to determine the presence, strength, and direction of association between covariates (explanatory variables) and the outcome variable. The Morisky medication adherence scale was used to assess the adherence status using > = 6 as adherent or < 6 as non adherent score.ResultsFour hundred and nine (409) study participants were interviewed with a response rate of 100%. The mean age of the respondents was 54.5 years with (Standard Deviation (SD) ± 13.58). The overall rate of good adherence was 67.2% (95% CI = 62.8, 71.6). Participants who had a favourable attitude towards antihypertensive medications (Adjusted odds ratio (AOR) = 9.88, 95% confidence interval (CI): 5.34, 18.27), having good patient- provider relationship (AOR = 4.25, 95% CI: 2.32, 7.86), having one (AOR = 4.36, 95% CI: 1.34, 14.12) or no (AOR = 3.38, 95% CI:1.01,11.31) co-morbidities, a long duration of treatment (AOR = 1.89, 95%CI: 1.07, 3.35), and a low medical cost (AOR = 2.06, 95% CI: 1.13, 3.76) had associations with good drug adherence for antihypertensive medication/s.ConclusionsThe prevalence of good drug adherence for anti-hypertensive medications in this study was high. Prevention of co- morbidities, making medical services accessible, and maintaining good client-provider interaction are of paramount importance for good drug adherence.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionsupporting

confidence: 65%

Section: Discussionmentioning

confidence: 57%

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Drug adherence for antihypertensive medications and its determinants among adult hypertensive patients attending in chronic clinics of referral hospitals in Northwest Ethiopia

Mekonnen

Gebrie

Eyasu

et al. 2017

BMC Pharmacol Toxicol

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“…Studies from two settings of Ethiopia were reported lower rates of non-adherence (26% and 19%) than the current study 11,16 . On the contrary, other literature findings were reported higher rates of non-adherence 17,18 . There are also other findings with comparable results non-adherence rate 19,20 .…”

Section: Discussionmentioning

confidence: 74%

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2017

IJPSR

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Background: The objective of this study was to assess drug therapy problems (DTPs) and their predictors among hypertensive patients on follow up at Dil-Chora Referral Hospital, Ethiopia. Methods: Hospital based cross-sectional study involving medical record review was conducted from February-to-April 2015 using a structured questionnaire and this was complemented by a face-to-face interview. Adult hypertensive patients aged ≥18 years who were on follow-up for at least 3-months were enrolled in the study using a convenient sampling method. Data analysis was done using SPSS software version 16.0. Multiple logistic regressions were fitted and odds ratios with 95%CI were calculated to identify factors associated with DTPs. Results: The study included 271 hypertensive patients. Mean age was 57.73±12.13. One hundred sixty three (60.1%) were females. More than half of the respondents (50.6%) had comorbid condition and diabetes was the most common. More than 71% of patients were found to have at least one DTP and the mean number of DTPs per patient was 1.39±1.28. Need additional drug therapy(62.4%) and non-adherence(32.8%) were the two most common DTPs. Presence of comorbidity (AOR=5.74, 95%CI; 2.49-13.00), taking ≥3 medications per day (AOR=7.04, 95%CI; 2.33-21.25), and uncontrolled blood pressure (BP) (AOR=7.68, 95%CI; 3.70-15.90) were factors associated with DTPs. Conclusions: DTPs are common among hypertensive patients on follow up and the most common were need additional drug therapy and non-adherence to medications. Pharmacist interventions in drug therapy would help physicians in early identification and prevention of DTPs so that a joint effort between physicians and pharmacists should be made.

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“…Rajpura and Nayak in their study reported a positive relationship between perception of the disease and positive beliefs about treatment in the elderly people with hypertension adhering the treatment (Rajpura & Nayak, 2014). Moreover, the results of the study conducted by Kang et al (2015) showed that patients who have higher perception of their disease are more adhering to their diet (Hacihasanoğlu & Gözüm, 2011). The results of the study conducted by Saarti et al showed that the mean scores of disease perception in patients who followed good treatment were higher than those who had weaker adherence to treatment, but the relationship was not significant (Saarti et al, 2016).…”

Section: Discussionmentioning

confidence: 91%

Assessing the Nutritional Knowledge, Disease Perception, and Adherence to Diet in Patients with Hypertension Admitted to Farshchian Cardiovascular Clinic in 2017

Khodaveisi¹,

Fakhrazizi²,

Mohammadi³

et al. 2018

JMBR

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Background and objective: adherence to diet by patients to control the blood pressure has always been challenging. The current study was conducted to evaluate the nutritional knowledge status and disease perception and adherence to diet in patients with hypertension.Methodology: In this quasi-experimental study conducted in 2017, 100 patients with hypertension admitted to Farshchian Cardiovascular Clinic were selected using convenient sampling method and by considering the inclusion criteria. The data were collected using demographic questionnaire, observing nutritional knowledge questionnaire, disease perception questionnaire, and adherence to diet questionnaire in patients with hypertension. Data were analyzed using spss16 software and descriptive statistics.Results: based on the results, mean score of knowledge was 4.73 ± 1.55. In this study 58% of the patients did not have knowledge on high fat diet, 56% of subjects did not have knowledge on red meat diet and 63% did not have knowledge on confection. The mean score of perception was 29.58 ± 3.94, which 38% of the patients believed that their diseases cannot be controlled with behavior and 43% were completely opposed that that their disease can lead into early death, and 56% opposed to restricting the diet. The mean score of follow-up of diet is 9.45 ± 2.27. In this study, 46% of patients did not adhere to their diet at home and 51% of patients did not adhere to their diet at workplace.Conclusion: Due to the lack of knowledge and perception of the disease and the effective follow-up of the diet, it is recommended that necessary measures to be taken to prevent complications of hypertension.

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Determinants of medication adherence and blood pressure control among hypertensive patients in Hong Kong: A cross-sectional study

Cited by 84 publications

References 24 publications

Drug adherence for antihypertensive medications and its determinants among adult hypertensive patients attending in chronic clinics of referral hospitals in Northwest Ethiopia

Drug adherence for antihypertensive medications and its determinants among adult hypertensive patients attending in chronic clinics of referral hospitals in Northwest Ethiopia

Untitled

Assessing the Nutritional Knowledge, Disease Perception, and Adherence to Diet in Patients with Hypertension Admitted to Farshchian Cardiovascular Clinic in 2017

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