“…11 In a review discussing reasons for discrepancies in left ventricular systolic function between preoperative transthoracic echocardiograms and TEE, Spencer et al tease out a number of important perioperative changes that can influence left ventricular ejection fraction determinations and may ultimately affect management. 12 They address progression of valvular, functional, and ischemic etiologies in the period between evaluations, key hemodynamic changes present under anesthesia and mechanical ventilation, drug effects, and anatomical considerations, specifically open chest and open pericardial physiology. Understanding and anticipating these changes and their contribution to left ventricular systolic function is crucial to our perioperative management of these complicated patients.…”