Determinants of Chronic Respiratory Symptoms among Pharmaceutical Factory Workers

Asfaw, Sahle; Enquselassie, Fikre; Tefera, Yifokire; Gizaw, Muluken; Wakuma, Samson; Woldemariam, Messay

doi:10.1155/2018/3815689

Cited by 21 publications

(31 citation statements)

References 18 publications

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“…According to a case control study by Asfaw et al among pharmaceutical workers of Ethiopia the adjusted odds ratio for previous history of respiratory diseases was 3.36 for the development of chronic respiratory symptoms in the future. 15 The study done by Galobardes et al among the historical cohort of male students who attended Glasgow university between 1948 and 1968 also revealed that a history of bronchitis in early life was moderately associated with chronic phlegm, dyspnea and a doctor's diagnosis of asthma in childhood, was very strongly associated with a doctor's diagnosis of bronchitis and emphysema in adulthood. 16 This may be due to the fact that previous respiratory disease could have damaged the normal respiratory functions which may cause airway obstruction later, lead to breathlessness and asthma.…”

Section: Discussionmentioning

confidence: 97%

Prevalence of chronic respiratory symptoms in an urban population of North Kerala

Vasudevan

Silpa

2019

Int J Community Med Public Health

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INTRODUCTIONWith the advent of antibiotics in 1940s, the importance of acute respiratory tract infection as a cause of high mortality and morbidity, declined rapidly in developed countries and also it is decreasing in developing countries. However the burden of chronic diseases of respiratory system is increasing day by day. Tobacco smoking, socio economic development, urbanization, associated life style changes and resulting increase in air pollution are undoubtedly the underlying causative factors. Apart from the discomfort of the symptoms and the prolonged treatment, chronic respiratory diseases are associated with a variety of serious complications, which result in high treatment costs, reduced quality of life, reduced productivity, and shortened life expectancy. ABSTRACTBackground: Chronic respiratory diseases are becoming a challenge to public health due to its high morbidity and mortality. Most of these diseases are preceded by variable periods of chronic respiratory symptoms. If chronic respiratory symptoms can be diagnosed and managed properly and timely, we can reduce the incidence and complication of chronic respiratory diseases. Methods: A community based cross sectional survey was conducted in 20 electoral wards of Calicut corporation of Northern Kerala among the adult resident population of 20-70 years to assess the prevalence of chronic respiratory symptoms such as chronic cough, phlegm, wheezing, breathlessness and nasal allergy and the factors associated with these chronic symptoms. The information was collected from 1384 eligible subjects selected by cluster sampling using British research council respiratory questionnaire. Results: About 9.2% (n=95) of study population had at-least one of the chronic respiratory symptoms. 1.8% (n=19) had all the chronic respiratory symptoms. Prevalence of various chronic respiratory symptoms was chronic cough (8.7%), Phlegm (14.3%), wheezing (8.5%), breathlessness (2.2%) and nasal allergy (14.5%). Advancing age, current smoking, family history and past history of various respiratory diseases are significantly associated with the development of chronic respiratory symptoms. Female gender, longer duration of stay in Calicut corporation and regular alcoholism were significantly associated with chronic phlegm in the study population. Wheezing, breathlessness and chronic nasal allergy was significantly higher among lower socio economic status. Conclusions: Prevalence of chronic respiratory symptoms is high among the urban population of Northern Kerala. Older age group, smoking, past and family history of respiratory diseases are the major risk factors associated with these respiratory symptoms.

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Section: Discussionmentioning

confidence: 97%

Prevalence of chronic respiratory symptoms in an urban population of North Kerala

Vasudevan

Silpa

2019

Int J Community Med Public Health

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“…Chronic respiratory symptoms were defined as the development of one or more of the symptom (s) of chronic cough, chronic phlegm, chronic wheezing, chronic shortness of breath, and chronic chest tightness which last (s) at least 3 months in 1 year. Detail definitions of each respiratory symptom were published elsewhere [1,2] and used in this study. The modified Medical Research Council (mMRC) Dyspnoea Scale was used as a measure of dyspnoea severity, ranged from 0 to 4, being 0 indicated no breathlessness and 4 indicated too breathless to leave the house.…”

Section: Operational Definitionsmentioning

confidence: 99%

“…Similarly, height was measured by using an erect height measuring device and approximated to 0.1 cm. Then, body mass index (BMI) of the study participants was calculated from their body weight and height using weight in kilogram / (height in meter) 2 as a formula [35].…”

Section: Data Collection Proceduresmentioning

confidence: 99%

“…Chronic respiratory symptoms including chronic cough, phlegm, wheezing, shortness of breath, and chest tightness could be the manifestations of chronic respiratory diseases, which are mainly developed as a result of exposure to occupational hazards [1,2]. Occupational exposures to respiratory hazards remain significant contributors to the global burden of respiratory disease [3] and the burden of occupational respiratory diseases is increasing worldwide [4].…”

Section: Introductionmentioning

confidence: 99%

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Chronic respiratory symptoms and pulmonary function status in Ethiopian agricultural workers: a comparative study

et al. 2020

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Background: Work-related respiratory disorders are major contributors to the global burden of respiratory diseases. Agricultural workers are exposed to a number of dusts, which may contribute to the development of respiratory disorders. However, the knowledge about the prevalence of respiratory symptoms and pulmonary function status in African farmers was limited. This study was conducted to assess the prevalence of chronic respiratory symptoms and pulmonary function status of Ethiopian farmers exposed to farming activities. Methods: A community based comparative cross sectional study was conducted among 288 agricultural workers (farmers) aged 18 to 65 years and 288 control subjects (non-agricultural workers). Data were collected by interviewer administered structured questionnaires adopted from British Medical Research Council respiratory questionnaire and American Thoracic Society Division of Lung Diseases questionnaire. Moreover, all study participants underwent spirometry. Results: The prevalence of chronic respiratory symptoms was higher in farmers than in controls, with significant difference for cough (20.5% vs. 9.0%, p = 0.001) and phlegm (19.1% vs. 9.0%, p = 0.001). Chronic respiratory symptoms among farmers were significantly associated with duration of agricultural exposure (p = 0.014). The mean values of all spirometric parameters were lower in farmers than in controls with significant difference for FVC, FEV1, FEF 25% , FEF 50% , FEF 25-75% and PEFR. Moreover, the mean values of all spirometric parameters of farmers have found to be decreased with increased duration of workplace exposure. Lung function test results also showed a higher prevalence of obstructive (15.6% vs. 10.8%, p = 0.085) and restrictive type (12.8% vs. 3.1%, p < 0.001) of pulmonary function impairment in farmers than in controls. However, the difference was not significant for obstructive type of impairment. Conclusion: This study indicated that farmers are at high risk for the development of chronic respiratory symptoms and reduced pulmonary function indices. Hence, a comprehensive occupational safety practices are important to maintain the respiratory health of farmers.

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“…Moreover, a recent study indicated the previous and family history of chronic obstructive respiratory disease, previous dusty working environment, and ever smoking were the main risk factors for chronic obstructive respiratory symptoms and its exacerbation [12]. Several risk factors like cigarette smoking, ambient particulate matter, household air pollution, occupational particulates, ozone, and second-hand smoke can cause COPD.…”

Section: Introductionmentioning

confidence: 99%

Mortality and its predictors among patients treated for acute exacerbations of chronic obstructive respiratory diseases in Jimma Medical Center; Jimma, Ethiopia: Prospective observational study

Mega¹,

Anbese²,

Yoo³

2020

PLoS ONE

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Background Chronic obstructive pulmonary disease (COPD) and asthma exacerbations are associated with ill health, increased mortality, and health care costs. However, there is limited evidence regarding mortality and its predictors among patients treated for COPD and asthma exacerbations in low-income nations, particularly in Ethiopia. Methods A-6 month prospective observational study was conducted from April 20-September 20, 2019. Data were collected on socio-demographic, baseline clinical characteristics and outcomes of asthma and COPD exacerbations. Data were entered into Epi-Data version 4.02.01 for cleaning and exported to STATA 14.0 for analysis. Kaplan-Meier (Log-rank test) was used to compare the baseline survival experience of the study participants and Cox proportional hazard regression analysis was conducted to determine the predictors of mortality. Adjusted hazard ratios (AHRs) with two-sided p-value <0.05 were considered statistically significant. Results A total of 130 patients (60% males) were included. The median (interquartile range (IQR)) age of the study participants was 59(50-70) years. The median (IQR) survival time to death was 17.5 (10-26) days. The total proportion of in-hospital mortality was 10.78% (14/130), and the incidence rate of mortality was 2.56 per 1000 person-years. The duration of oxygen therapy �16hours/day (AHR = 6.330, 95% CI [1.092-36.679], and old age (AHR = 1.066, 95% CI [1.0001-1.136] were the independent predictors of in-hospital mortality.

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Determinants of Chronic Respiratory Symptoms among Pharmaceutical Factory Workers

Cited by 21 publications

References 18 publications

Prevalence of chronic respiratory symptoms in an urban population of North Kerala

Prevalence of chronic respiratory symptoms in an urban population of North Kerala

Chronic respiratory symptoms and pulmonary function status in Ethiopian agricultural workers: a comparative study

Mortality and its predictors among patients treated for acute exacerbations of chronic obstructive respiratory diseases in Jimma Medical Center; Jimma, Ethiopia: Prospective observational study

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