“…11 Of the 21 studies, the most common conditions were as follows: cerebral palsy (n = 5), cystic fibrosis (n = 4), and CHD (n = 4). Most studies used generic QoL questionnaires that have both The majority of these studies reported that a child' s perception of QoL differed from that of his or her parents, with parents frequently underestimating their children' s QoL, 11,49,56 in particular in subjective domains (eg, emotional and psychosocial). 34,45,47,49,51,52,58,59 Despite reports of weak correlation 11,47,48 or large differences in mean scores 58 between selfreports and proxy reports for the emotional domain, White-Koning et al 11 demonstrated that the self-report-proxy agreement rate for "emotions" was higher (44%) than for most domains (range: 25%-40%).…”