Determinants of Asthma Attack Among Adult Asthmatic Patients Attending at Public Hospitals of West Shoa Zone, Oromia Regional State, Ethiopia, 2021: Case–Control Study

Abstract

Background: Asthma attacks are life-threatening episodes that place a costly burden on the individual and the community in both high-and low-income countries including Ethiopia. There is scant information on the determinant of it in the study area. Objective: To identify determinants of asthma attack among adult asthmatic patients attending at public hospitals of West Shoa Zone, Oromia Regional State, Ethiopia. Methods: An institutional-based unmatched case-control study design was conducted. In this study, 300 participants (100 cases and 200 controls) were included. A pre-tested structured questionnaire was used to collect data. After the data were entered into Epidata version 3.1, it was exported to SPSS version 25 for analysis. First, bivariable logistic regression was performed. Independent variables with a p-value < 0.25 in binary logistic regression were entered into a multivariable logistic regression model. In the multivariable logistic regression model, independent variables with a p-value < 0.05 were considered to be significant determinants of the outcome variable of the study. Results: This finding identified that upper respiratory tract infection (

The relationship between obstructive sleep apnea and asthma severity and vice versa: a systematic review and meta-analysis

“…In Part A, 13 studies [ 7 – 19 ] examined the effect of OSA on lung function and ACT in asthma with 1,111 subjects (Table 1 ), and 7 studies [ 20 – 26 ] examined the relationship between asthma and varying severity of OSA with 15,266 subjects (Table 2 ). In Part B, 10 studies [ 9 , 22 , 25 , 27 – 33 ] examined the effect of asthma on PSG and ESS in OSA patients with 9,666 subjects (Table 3 ), and 11 studies [ 10 , 13 – 15 , 34 – 40 ] examined the relationship between OSA and varying severity of asthma with 1869 subjects (Table 4 ). Other characteristics of the included studies are presented in each table.…”

“…Although more severe OSA aggravated asthma control, the meta-analysis came out that it was not associated with the risk of OSA (OR = 0.87, P = 0.047, I2 = 0%). In the two included studies with the largest population (N = 8400), AHI was slightly lower in asthmatic than in non-asthmatic patients with OSA [ 25 , 32 ] (26.2 vs 23.0 events/h, P < 0.001; 12.6 vs 11.3 events/h, P < 0.001). In terms of baseline characteristics, those without asthma were more likely to be male and older than those with asthma.…”