Detectors for in vivo range and dose verification in proton therapy

Abstract

Particle detection instrumentation to address the in vivo verifications of proton dose and range is under development as part of a proton therapy research program focused on patient quality assurance. For in vivo proton range verification, a collimated gamma detector array is under construction to indirectly measure the position of the Bragg peak for each proton beam spot to within 1-2 mm precision. For dose flux verification, a proton fluence detector based on the technology of the Micromegas is under construction. This detector has an active area of about 100 cm 2 , coordinate resolution of better than 1 mm, and handling of incident proton beam fluxes of 10 9 -10 13 particles/s.

GEANT4 Study of Proton–Body Interactions

“…This work is born in support to the project of Arizona State University [7] to develop an out-of-the-body gamma ray detectors that can help determine the location of the proton-tissue interactions during proton therapy. Next we discuss the interactions of protons with body parts and the production of gamma rays, the setup of the GEANT4 simulation, the analysis of the gammas produced, and the result of the simulations.…”