Detection of target-site and metabolic resistance to pyrethroids in the bed bug Cimex lectularius in Berlin, Germany

Pan, Arlette Vander; Kuhn, Carola; Schmolz, Erik; Samson‐Himmelstjerna, Georg von; Krücken, Jürgen

doi:10.1016/j.ijpddr.2020.11.003

Cited by 5 publications

(1 citation statement)

References 54 publications

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“…While in another study fenitrothion and imidacloprid resistance showed an association between cuticle thickness and resistance. but, the association may be tenuous because the resistance mechanism is multifactorial in C. hemipterus , and these mechanisms, in the C. hemipterus population were, caused by both M 918I and L1014F mutations, which is likely related to cuticle thickness ( 15 ), as well as, in bed bugs populations, there are multiple resistance mechanisms against pyrethroids, that seem caused by several point mutations in the voltage-sensitive sodium channel α-subunit gene and increased metabolic detoxification by cytochrome P450, all contributing to knockdown resistance (kdr)( 16 , 17 ).…”

Section: Discussionmentioning

confidence: 99%

Testing the Sensitivity of the Tropical Bed Bug Cimex hemipterus (Hemiptera: Cimicidae) to Deltamethrin, Phoxim and Propetamphos in Eastern Iran

Babagolzadeh,

Nasrabadi,

Moghaddas

et al. 2024

JAD

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Background: Bedbugs are nocturnal ectoparasites that have made a comeback after 20 years and have become one of the main challenges for pest control methods worldwide. Monitoring chemical pesticide resistance is crucial for identifying the best bed bugs management strategies to effectively manage arthropods. This study aims to assess the susceptibility of Cimex hemipterus (Hemiptera: Cimicidae) collected from different parts of Khorasan-Razavi Province, (northeast of Iran) to deltamethrin (pyrethroid), phoxim (organothiophosphate) and propetamphos (phosphoramidate). Methods: This study was conducted from Dec 2020 to May 2021. The efficacy of three insecticides (deltamethrin, phoxim, and propetamphos) on adult C.hemipterus was assessed using a bioassay method recommended by the World Health Organization (WHO),. Concentrations of deltamethrin used were 10, 20, 40, 80, 160, 320, 640, 1280, and 2560 ppm, while concentrations of phoxim and propetamphos were 10, 40, 160, and 320 ppm. The bed bugs were continuously exposed to the insecticide for 24 hours, and mortality was assessed at regular intervals during the observation period. The concentration-response data were subjected to POLO-PC software and data were analyzed by the one-way and two-way ANOVA procedures. Results: The lethal concentration fifty values of deltamethrin, phoxim and propetamphos on the examined bed bugs were 0.551, 0.148 and 0.237 ppm, respectively. Insecticide effects of phoxim were significantly higher (P≤ 0.05) compared to each of either deltamethrin and propetamphos agents. Conclusions: The insecticide effects of phoxim against bed bugs were significantly higher compared to each of either deltamethrin or propetamphosinsecticides.

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Section: Discussionmentioning

confidence: 99%

Testing the Sensitivity of the Tropical Bed Bug Cimex hemipterus (Hemiptera: Cimicidae) to Deltamethrin, Phoxim and Propetamphos in Eastern Iran

Babagolzadeh,

Nasrabadi,

Moghaddas

et al. 2024

JAD

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Decade long upsurge in mutations associated with pyrethroid resistance in bed bug populations in the USA

et al. 2022

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The Efficacy of a Pyrethroid-impregnated Mattress Liner on Multiple International Strains ofCimex lectularius(Hemiptera: Cimicidae) andCimex hemipterus(Hemiptera: Cimicidae)

Leong

Lee

Singham

et al. 2022

Journal of Economic Entomology

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Modern bed bugs are resistant to multiple insecticide classes, particularly the pyrethroids. The efficacy of pyrethroid-impregnated mattress liners marketed for bed bug management has been variable. This study evaluated the efficacy of a permethrin-impregnated mattress liner, ActiveGuard, against 24 bed bug strains, consisting of both Cimex hemipterus (F.) and Cimex lectularius L. A ‘mat assay’, employing an allethrin-impregnated mat, was used to establish the pyrethroid resistance profile of all strains. Three experiments were conducted to evaluate the effect of ActiveGuard exposure on bed bug knockdown: 1) exposing the bed bugs continuously on the liner for up to 24 d, 2) holding the bed bugs on the liner for either 4 or 6 h, and 3) placing a noninsecticide treated fabric above the liner with the bed bugs held continuously on top. Our results indicated that all modern strains (collected within the last 15 years during the current resurgence) were pyrethroid-resistant, although the magnitude of resistance was highly variable between strains. In the continuous exposure study, an incomplete knockdown was recorded for most modern bed bug strains, with some having no knockdown even up to 7 d of constant exposure. In the 4 or 6 h exposure study, the level of knockdown was reduced even further, and very few bed bugs were knocked down in the double fabric study. The results of this study indicate that pyrethroid-impregnated mattress liners are not likely to be effective in the management of most modern bed bug infestations involving either C. hemipterus or C. lectularius.

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Detection of target-site and metabolic resistance to pyrethroids in the bed bug Cimex lectularius in Berlin, Germany

Cited by 5 publications

References 54 publications

Testing the Sensitivity of the Tropical Bed Bug Cimex hemipterus (Hemiptera: Cimicidae) to Deltamethrin, Phoxim and Propetamphos in Eastern Iran

Testing the Sensitivity of the Tropical Bed Bug Cimex hemipterus (Hemiptera: Cimicidae) to Deltamethrin, Phoxim and Propetamphos in Eastern Iran

Decade long upsurge in mutations associated with pyrethroid resistance in bed bug populations in the USA

The Efficacy of a Pyrethroid-impregnated Mattress Liner on Multiple International Strains ofCimex lectularius(Hemiptera: Cimicidae) andCimex hemipterus(Hemiptera: Cimicidae)

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