Detection of maduramycin residues in the tissues of chickens and pheasants by the screening test for antibiotic residues (STAR)

Kožárová, I.; Mačanga, Ján; Goldová, M.; Major, Péter; Tkáčiková, Soňa

doi:10.1080/19440049.2011.561879

Cited by 8 publications

(3 citation statements)

References 16 publications

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“…Just lately it has been proven that maduramicin (Bodi et al 2012) and SMD (Olejnik et al 2014) can transfer from feed to eggs in larger proportions than was expected. Similar data were obtained in an experiment performed on broiler chickens for maduramicin, which was found in all tested matrices (thigh and breast muscle, gizzard, liver, heart, kidney, spleen, lung) (Kožárová et al 2011). To the best of our knowledge, the transfer of SMD into tissues has only been investigated once previously (Lynch et al 1992).…”

Section: Introductionsupporting

confidence: 80%

Distribution of semduramicin in hen eggs and tissues after administration of cross-contaminated feed

Olejnik

Szprengier-Juszkiewicz

Jedziniak

2014

Food Additives & Contaminants: Part A

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Semduramicin is an ionophore coccidiostat used in the poultry industry as a feed additive. Cross-contamination of feeds for non-target animals with semduramicin is unavoidable. However, it is not known whether undesirable residues of semduramicin may occur in food after cross-contaminated feed is administered to animals. The aim of the work was to determine the levels of semduramicin in hen eggs (yolks and albumen) and tissues (liver, muscle, spleen, gizzard, ovarian yolks and ovaries) after administration of feed contaminated with 0.27 mg kg(-1) of this coccidiostat. The residues were determined using LC-MS/MS. The distribution pattern confirmed the high lipophilicity of semduramicin. Residues were found mainly in egg yolks (28.8 µg kg(-1)), ovarian yolks (19.5 µg kg(-1)) and liver (2.57 µg kg(-1)), while hens' muscle was free from semduramicin (LOD = 0.1 µg kg(-1)). Among edible tissues, the maximum level (2 µg kg(-1)) was exceeded only in the liver.

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Section: Introductionsupporting

confidence: 80%

Distribution of semduramicin in hen eggs and tissues after administration of cross-contaminated feed

Olejnik

Szprengier-Juszkiewicz

Jedziniak

2014

Food Additives & Contaminants: Part A

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“…calidolactis to the ionophoric coccidiostats under in vitro conditions (Kožárová and Máté, 2000), and also the positive responses on the STAR test plates seeded with B. stearothermophilus var. calidolactis and with the Premi ® Test and the Total Antibiotics after the screening of tissue samples of experimental broiler chickens receiving in-feed coccidiostats (Kožárová et al, 2002(Kožárová et al, , 2008(Kožárová et al, , 2011a(Kožárová et al, , 2011bTkáčiková et al, 2010Tkáčiková et al, , 2012.…”

Section: Inhibition Tests For Antimicrobial Residuesmentioning

confidence: 99%

Comparison of Four Microbiological Inhibition Tests for the Screening of Antimicrobial Residues in the Tissues of Food-Producing Animals

Gondová

Kožárová

Poláková

et al. 2014

Italian Journal of Animal Science

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“…Given the use of calipers for the measurement of IZs associated with antibiotic residue presence, the STAR method could be defined as a semi-quantitative method used as a qualitative screening assessment; where the diameter of the IZ produced theoretically correlates and so is directly proportional to the level/concentration of antibiotic residues found within a sample [11,12,16]. Note that there is some subjectivity in relation to determining at which points to measure on an IZ and also the respective distance of the IZ.…”

Section: Sample Analysismentioning

confidence: 99%

Broad Spectrum Detection of Antibiotic Residues in Poultry Meat by a Multi-Plate Assay

Watkins

Kožárová

2019

Folia Veterinaria

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The objective of this study was to use the “Screening test for antibiotic residues” (STAR) as a broad-spectrum detection method for antibiotic residues in poultry meat. The STAR method is a microbiological inhibition assay (a five plate test) where the development of inhibition zones (IZs) indicates the presence of antibiotic residues in meat samples. By using the STAR method, in a total of 13 poultry products providing 18 meat samples (14 muscle and 4 skin) and 18 corresponding juice samples, 11 out of the 18 samples were positive for containing antibiotic residues. Based on muscle alone (which is the matrix validated for use in the STAR method), 6 of the 14 muscle samples were positive for antibiotic residues. The STAR method as a screening technique proves advantageous as it is relatively easy to perform and of a low cost. Furthermore, the STAR method not only indicates the presence or absence of antibacterial substances, but simultaneously, a positive sample gives an indication of the antibiotic family present due to the use of five different bacterial test organisms. Families of antibiotics pre-identified due to positive samples in the results of this study include aminoglycosides (one out of 18), beta-lactams and sulphonamides (6 out of 18), and macrolides (5 out of 18). Such pre-identification of the antimicrobial families allows for a targeted confirmatory analysis. However, one could argue that the STAR method is laborious and time consuming. Overall, given the potential for false positive/negative results, further confirmatory method analysis of the samples must be performed to ensure that the results and conclusions drawn here are true.

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Detection of maduramycin residues in the tissues of chickens and pheasants by the screening test for antibiotic residues (STAR)

Cited by 8 publications

References 16 publications

Distribution of semduramicin in hen eggs and tissues after administration of cross-contaminated feed

Distribution of semduramicin in hen eggs and tissues after administration of cross-contaminated feed

Comparison of Four Microbiological Inhibition Tests for the Screening of Antimicrobial Residues in the Tissues of Food-Producing Animals

Broad Spectrum Detection of Antibiotic Residues in Poultry Meat by a Multi-Plate Assay

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