Detection of Immunoglobulin G (IgG) and Immunoglobulin M (IgM) Antibodies Using Circular Photonic Crystal Fiber Sensor

Nizar, S. Mohamed; Kesavaraman, B.; Priyanka, E.; Jayasri, R.

doi:10.1088/1742-6596/1717/1/012039

Cited by 3 publications

(2 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, the detection of antibodies like immunoglobulin M (IgM) and immunoglobulin G (IgG) response is also proposed for the tracking of the COVID virus [76,77]. Reported RI values of 1.343-1.3493 for IgG (minimum and maximum values) and 1.34414-1.3448 for IgM indicated the potential of our proposed structure for sensing multiple antibodies simultaneously [78].…”

Section: Application-level Perspectives Across Biosensingmentioning

confidence: 99%

Matrix shaped plasmonic hybrid nanostructure with direction-dependent functionality for multianalyte detection and biosensing

S¹,

Francis²,

Ramachandran³

et al. 2022

J. Phys. D: Appl. Phys.

View full text Add to dashboard Cite

A Surface plasmon resonance (SPR) based hybrid nanosystem with the competence of single and multiple analytes analysis is demonstrated using a symmetry modified sensory platform for promising application in biosensing. Plasmonic properties of the designed 2×2 matrix system arising from higher-order plasmonic modes generated near groove positions in the structure are analyzed numerically and calibrated for enhanced sensor performance and multi-functionality. The asymmetric defect/ percentage of asymmetry (∆) in the structure incorporated by means of a position-wise shift of Ag nanodisc exhibits pivotal results in performance parameters, including intra channel sensitivity (Sintra), channel separation factor (CHfactor), Figure of merit (FOM) and Q-factor. The pairs of sensing windows of the hybrid structure show a geometric symmetry along the x and -x direction and an asymmetry along its perpendicular (y and -y). Among the symmetric and asymmetric channels, spatially resolved plasmonic modes of asymmetric channels facilitate the multi quantification of analytes in a single stimulation, whereas symmetric ones confirm the presence of the different analytes in the given specimen. With the sensor function flexible to light incidence direction, the matrix system can be effectively employed across medical diagnostics and healthcare monitoring.

show abstract

Section: Application-level Perspectives Across Biosensingmentioning

confidence: 99%

Matrix shaped plasmonic hybrid nanostructure with direction-dependent functionality for multianalyte detection and biosensing

S¹,

Francis²,

Ramachandran³

et al. 2022

J. Phys. D: Appl. Phys.

View full text Add to dashboard Cite

show abstract

“…The antibody such as immunoglobulin G (IgG) is used as recognition element to detect the SARS-CoV-2. The RI of IgG is taken as 1.3430 [37] and the dimension of IgG is 13.7 nm × 8.4 nm × 4.0 nm [38]. The diameter of each hole of the designed PC is d = 2r = 900 nm with a height of h = 600 nm and volume V = π r 2 h = 0.381 µm 3 .…”

Section: Proposed Pc Based Biosensor With the Layers Of Recognition E...mentioning

confidence: 99%

Computational study of 2D photonic crystal based biosensor for SARS-COV-2 detection

Miyan

Agrahari

Gowre³

et al. 2023

Meas. Sci. Technol.

View full text Add to dashboard Cite

A computational study to design a 2D-photonic crystal (PC) structure with a fluorescence-based biosensor has been demonstrated for the detection of the SARS-COV-2 virus in the lungs. The proposed sensor can detect the different concentrations of the virus without any pretreatment of the sample. The virus detection is performed by measuring the mid-gap wavelength from the dispersion diagram and a redshift in the mid-gap wavelength has been observed as the concentration of virus increases in the lung tissue. The plane wave expansion (PWE) method is used to determine the dispersion diagram of the proposed PC. The interaction of incident light with the proposed PC-based biosensor has been analyzed to evaluate the shift in the mid-gap wavelength. A maximum sensitivity of about 1459.3 nm/RIU is obtained for r/a=0.45 with a mid-gap wavelength shift of 145.93 nm at =1.49 concentration of SARS-COV 2. Moreover, a very-small detection time has been observed with the proposed device as compared to conventional methods. This study provides a simple process to detect the presence of a virus within a short period and could be helpful in the development of a direct and easy-to-use portable detection kit in the future.

show abstract

Highly sensitive fiber optic biosensors with graphene-MoS₂ heterostructure for hemoglobin detection

Xiao

Yang

et al. 2022

Opt. Continuum

View full text Add to dashboard Cite

Two-dimensional materials, which can be used to modify sensor surfaces to increase sensor sensitivity, have important research in the field of sensors. In this paper, we design a highly sensitive D-shaped photonic crystal fiber sensor with graphene-MoS2 heterostructure for hemoglobin detection. The research utilized the finite element method and involved addition of different layers of graphene and MoS2 to the optical fiber sensing area, and it was determined that the hybrid nano-heterostructures made of monolayer graphene and bilayer MoS2 provided the greatest improvement in sensor performance. The sensor shows excellent detection performance in 1.33∼1.38 refractive index units. Using incident light in the wavelength ranges of 650 nm and 850 nm, the proposed sensor has a maximum wavelength sensitivity of 4700 nm/RIU, a maximum amplitude sensitivity of 327.5 RIU-1, and a resolution of 2.17×10−5 RIU. The range of hemoglobin concentrations detected with this sensor was 0 g/L∼241 g/L, with an average sensitivity of 0.7 nm/(g/L). A fiber biosensor was enhanced with graphene-MoS2 hybrid nanostructures, which exhibit excellent photoelectric properties and detection performance, enabling highly sensitive, highly accurate, and real-time hemoglobin detection. The result shows the significant research value and application prospects in the field of biomedical detection.

show abstract

Detection of Immunoglobulin G (IgG) and Immunoglobulin M (IgM) Antibodies Using Circular Photonic Crystal Fiber Sensor

Cited by 3 publications

References 5 publications

Matrix shaped plasmonic hybrid nanostructure with direction-dependent functionality for multianalyte detection and biosensing

Matrix shaped plasmonic hybrid nanostructure with direction-dependent functionality for multianalyte detection and biosensing

Computational study of 2D photonic crystal based biosensor for SARS-COV-2 detection

Highly sensitive fiber optic biosensors with graphene-MoS₂ heterostructure for hemoglobin detection

Contact Info

Product

Resources

About

Detection of Immunoglobulin G (IgG) and Immunoglobulin M (IgM) Antibodies Using Circular Photonic Crystal Fiber Sensor

Cited by 3 publications

References 5 publications

Matrix shaped plasmonic hybrid nanostructure with direction-dependent functionality for multianalyte detection and biosensing

Matrix shaped plasmonic hybrid nanostructure with direction-dependent functionality for multianalyte detection and biosensing

Computational study of 2D photonic crystal based biosensor for SARS-COV-2 detection

Highly sensitive fiber optic biosensors with graphene-MoS2 heterostructure for hemoglobin detection

Contact Info

Product

Resources

About

Highly sensitive fiber optic biosensors with graphene-MoS₂ heterostructure for hemoglobin detection