Detection of human papillomavirus genotypes associated with mucopurulent cervicitis and cervical cancer in Changchun, China

Liu, Wei; Enqi, Wu; Yu, Xianghui; Feng, Liang; Jiang, Chunlai; Xiao, Zhengguo; Kong, Wei

doi:10.1016/j.ijgo.2012.07.032

Cited by 12 publications

(22 citation statements)

References 12 publications

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“…The overall prevalence of HPV infection in the CC group (84.4%) was similar to the rate of 85.9% reported in a meta-analysis of CC in Asia (Bao et al, 2008b). Like other regions worldwide, HPV16 was the predominant type (55.8%, 43/77) identified among CC patients in the present study; very similar to the previously reported rate in a meta-analysis of HPV in mainland China and Hong Kong (58.7%) (Bao et al, 2008a), but it was significantly lower than the rate found in Changchun, China (87.7%, 57/65) (Liu et al, 2013). As we know, except for HPV16 appears most frequently, the probability of other genotype can vary in different countries or areas.…”

Section: Discussionsupporting

confidence: 87%

“…The difference may partially be due to our method is more sensitive than that of they used. The prevalence of oncogenic HPV infection in this group was up to 88.1% (37/42), simlar to that (77.5%) of Liu et al (2013). HPV16, 58, 59-as oncogenic genotypes-were predominant in MPC group, indicative of MPC patients should be made aware of the danger of developing CC.…”

Section: Discussionmentioning

confidence: 62%

“…DNA samples were extracted from the cervical swabs as previously described (Liu et al, 2013). Briefly, a cervical specimen was collected from each patient using a cotton swab and stored at −80°C.…”

Section: Methodsmentioning

confidence: 99%

“…DNA samples from the MPC and control groups were screened for HPV infection by nested PCR using L1 MY09/11-GP5+/6+ consensus primers (Liu et al, 2013).…”

Section: Methodsmentioning

confidence: 99%

“…The inflammatory condition of the cervix among patients with MPC is thought to be the consequence of infection with sexually acquired pathogens, such as Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Mycoplasma genitalium (MG), Gardnerella vaginalis (GV) and Trichomonas vaginalis (TV), Mycoplasma hominis (MH), herpes simplex virus type 2 (HSV-2) (Paavonen et al, 1986). Furthermore, several studies have indicated that MPC may accompany infection with HPV (Liu et al, 2013).…”

Section: Human Papillomavirus Genotypes Associated With Mucopurulent mentioning

confidence: 99%

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Human Papillomavirus Genotypes Associated with Mucopurulent Cervicitis and Cervical Cancer in Hangzhou, China

Shen¹,

Liu²

2013

Asian Pacific Journal of Cancer Prevention

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Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 62%

Section: Methodsmentioning

confidence: 99%

“…DNA samples from the MPC and control groups were screened for HPV infection by nested PCR using L1 MY09/11-GP5+/6+ consensus primers (Liu et al, 2013).…”

Section: Methodsmentioning

confidence: 99%

Section: Human Papillomavirus Genotypes Associated With Mucopurulent mentioning

confidence: 99%

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Human Papillomavirus Genotypes Associated with Mucopurulent Cervicitis and Cervical Cancer in Hangzhou, China

Shen¹,

Liu²

2013

Asian Pacific Journal of Cancer Prevention

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Prevalence of high‐risk human papillomavirus infection among women in Shaanxi province of China: A hospital‐based investigation

Cao

Zhang

et al. 2016

Journal of Medical Virology

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This study aimed to investigate the characteristics of female high-risk human papillomavirus (HR-HPV) infection in Shaanxi province of China. A total of 14 111 women were enrolled for HPV genotyping test, and a cytology, and/or cervix biopsy were performed in partial women. Of these women, the HPV infection rate was 30.21%, and 26.73% were caused by HR-HPV. The most common HR-HPV genotypes were HPV-16, HPV-58, HPV-52, HPV-18, and HPV-31. The prevalence of HR-HPV among women older than 50 years was significantly higher than the other groups (P < 0.05). The main carcinogenic genotypes were HPV-16, HPV-18, HPV-58, HPV-52, and HPV-31. HPV-16 and HPV-18 combined caused 80.79% of cervical cancer cases. The infection with multiple HR-HPVs was not a risk factor for cervical lesions. In conclusion, HPV infection was common among women in Shaanxi province. Women older than 50 years were a high-risk group for HR-HPV infection and cervical cancer. HPV-16 and HPV-18 were the main carcinogenic genotypes in this region.

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Prevalence and genotype distribution of human papillomavirus in women with cervical cancer or cervical intraepithelial neoplasia in Henan province, central China

Chen

Zheng

Gao

et al. 2020

Journal of Medical Virology

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To evaluate the prevalence of human papillomavirus (HPV) infection and its genotype among women with cervical lesions in Henan Province, central China. A total of 1317 cervical scrapes from patients with cervical intraepithelial neoplasia 1 (CIN1) (n = 91), CIN2/3 (n = 466), and cervical cancer (CC; n = 760) were collected from 2013 to 2018, and then tested for HPV genotypes using polymerase chain reaction followed by flow‐through hybridization assay. The prevalence of HPV was 62.64% for patients with CIN1, 86.91% for patients with CIN2/3%, and 89.21% for patients with CC. In total, the HPV prevalence was 86.56%, and the most common HPV type was HPV16 (58.77%) followed by HPV58 (10.33%), 18 (7.67%), 52 (6.61%), and 33 (5.54%). In this study, the high‐risk HPV cumulative attribution rate of nine‐valent vaccine coverage was markedly higher than that of bivalent or quadrivalent vaccine coverage in each histopathological category or overall (P < .001). Single HPV infection was the main infection category in each histopathological diagnosis, and the total infection rate was 65.83% (867/1317; P < .001). The prevalence of HPV16 or single HPV infection increased with the severity of cervical lesions (P < .001). HPV16, 58, 18, 52, and 33 may be predominant high‐risk factors for cervical lesions in Henan Province. The nine‐valent prophylactic HPV vaccine is more effective than a bivalent or quadrivalent vaccine for protecting women from CC in the region.

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Detection of human papillomavirus genotypes associated with mucopurulent cervicitis and cervical cancer in Changchun, China

Abstract: Infection with HPV was prevalent among Chinese women with MPC or CC. Furthermore, the high prevalence of oncogenic genotypes observed among HPV-positive patients with MPC suggests that this group is at increased risk of developing CC.

Cited by 12 publications

References 12 publications

Human Papillomavirus Genotypes Associated with Mucopurulent Cervicitis and Cervical Cancer in Hangzhou, China

Human Papillomavirus Genotypes Associated with Mucopurulent Cervicitis and Cervical Cancer in Hangzhou, China

Prevalence of high‐risk human papillomavirus infection among women in Shaanxi province of China: A hospital‐based investigation

Prevalence and genotype distribution of human papillomavirus in women with cervical cancer or cervical intraepithelial neoplasia in Henan province, central China

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