Detection of focal liver lesions in cirrhotic liver using contrast-enhanced ultrasound

Wong, Grace Lai–Hung; Xu, Hui‐Xiong; Xie, Xian-Jin

doi:10.4329/wjr.v1.i1.25

Cited by 16 publications

(15 citation statements)

References 82 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is believed that the contrast is uptaken by Kupffer cells or remains in the hepatic sinusoids in the late phase. There are new contrast agents that provide the additional post-vascular or Kupffer phase that allows an assumption of the degree of malignancy based on Kupffer function [8] . The portal and late phase enhancement can give important information about the lesion's behavior.…”

Section: Contrast-enhanced Sonographymentioning

confidence: 99%

Contrast-enhanced ultrasound in diagnosis and characterization of focal hepatic lesions

Molins¹

2010

WJR

View full text Add to dashboard Cite

The extensive use of imaging techniques in differential diagnosis of abdominal conditions and screening of hepatocellular carcinoma in patients with chronic hepatic diseases, has led to an important increase in identification of focal liver lesions. The development of contrastenhanced ultrasound (CEUS) opens a new window in the diagnosis and follow-up of these lesions. This technique offers obvious advantages over the computed tomography and magnetic resonance, without a decrease in its sensitivity and specificity. The new second generation contrast agents, due to their intravascular distribution, allow a continuous evaluation of the enhancement pattern, which is crucial in characterization of liver lesions. The dual blood supply in the liver shows three different phases, namely arterial, portal and late phases. The enhancement during portal and late phases can give important information about the lesion's behavior.Each liver lesion has a different enhancement pattern that makes possible an accurate approach to their diagnosis. The role of emerging techniques as a contrastenhanced three-dimensional US is also discussed. In this article, the advantages, indications and technique employed during CEUS and the different enhancement patterns of most benign and malignant focal liver lesions are discussed.

show abstract

Section: Contrast-enhanced Sonographymentioning

confidence: 99%

Contrast-enhanced ultrasound in diagnosis and characterization of focal hepatic lesions

Molins¹

2010

WJR

View full text Add to dashboard Cite

show abstract

“…It is now an era of diagnostic and interventional US [31][32][33] . Dr. Xu's studies in the fields of 3D US, interventional US, and CEUS has greatly enriched the use of US in diagnosis and treatment.…”

Section: Resultsmentioning

confidence: 99%

Era of diagnostic and interventional ultrasound

Xu¹

2011

WJR

View full text Add to dashboard Cite

It is an era of diagnostic and interventional ultrasound (US). Various new techniques such as three-dimensional US (3D US), interventional US, and contrastenhanced US (CEUS) have been introduced into clinical practice. Dr. Xu and his colleagues have taken advantage of these techniques and carried out a series of relevant studies. Their use of 3D US in the liver, gallbladder, liver tumor volumetry, guidance for ablation, and 3D CEUS has widened the application of 3D US in the clinic. They found that prognosis in patients with hepatocellular carcinoma (HCC) after thermal ablation with curative intent was determined by treatment response to ablation, pretreatment serum AFP, and liver function reserve. Tumor response to treatment was the most predictive factor for long-term survival. They compared the use of percutaneous microwave ablation and radiofrequency ablation for the treatment of HCC and found that both are effective methods in treating HCCs. The local tumor control, complications related to treatment, and long-term survival were equivalent for the two modalities. They first compared the enhancement patterns of HCC and intrahepatic cholangiocarcinoma (ICC) and proposed the diagnostic clues for ICC, liver angiomyolipoma (AML), gallbladder cancer, renal carcinoma, and renal AML, which have greatly enhanced the role of CEUS in the clinic. They also evaluated the diagnostic performance of CEUS in characterizing complex cystic focal liver lesions and the agreement between two investigators with different experience levels; and found that CEUS is especially useful for the young investigator. They assessed the effect of anti-angiogenic gene therapy for HCC treated by microbubble-enhanced US exposure and concluded that gene therapy mediated by US exposure enhanced by a microbubble contrast agent may become a new treatment option for HCC.

show abstract

“…Several techniques have been devised to overcome the limitations of B-mode US, and CEUS can serve as a good rescue method. In one report, sensitivity and overall accuracy of detection of HCCs smaller than 2 cm improved with CEUS from 29% to 80% and 64% to 87%, respectively (21).…”

Section: Discussionmentioning

confidence: 99%

Contrast-enhanced ultrasound-guided radiofrequency ablation in inconspicuous hepatocellular carcinoma on B-mode ultrasound

Kim¹,

Kim²,

Shin³

et al. 2017

Turk J Gastroenterol

View full text Add to dashboard Cite

Recently, novel contrast agents for ultrasound have been developed to improve the diagnostic yield. SonoVue (Bracco, Milan, Italy) and Sonazoid (Daiichi-SanTurk J Gastroenterol 2017; 28: 446-52 Contrast-enhanced ultrasound-guided radiofrequency ablation in inconspicuous hepatocellular carcinoma on B-mode ultrasound Eui Joo Kim , Yun Soo Kim , Seung Kak Shin , Oh Sang Kwon , Duck Joo Choi , Ju LiverOriginal Article

show abstract

Detection of focal liver lesions in cirrhotic liver using contrast-enhanced ultrasound

Cited by 16 publications

References 82 publications

Contrast-enhanced ultrasound in diagnosis and characterization of focal hepatic lesions

Contrast-enhanced ultrasound in diagnosis and characterization of focal hepatic lesions

Era of diagnostic and interventional ultrasound

Contrast-enhanced ultrasound-guided radiofrequency ablation in inconspicuous hepatocellular carcinoma on B-mode ultrasound

Contact Info

Product

Resources

About