Detection of Fatty Acids Profile in Human Saliva with Special Reference to Ovulation

Alagendran, S; Archunan, Govindaraju; Kumar, K. Ramesh; Rengarajan, Rengasamy Lakshminarayanan; Guzmán, Rosalinda Guevara

doi:10.5539/ijb.v3n1p87

Cited by 4 publications

(3 citation statements)

References 26 publications

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“…Saliva samples are easy to obtain without pain and can be obtained on a daily basis (Hofman, 2001). It is known that saliva ferning depends principally on the electrolytes concentration (especially NaCl) and chemo-physical properties of the mucins it contains (sialic acid) (Alagendran et al, 2007;2009;Pattanasuttinont et al, 2007). The estrogens increase the water content in mid-cycle and determine the most favorable condition, optimal proportion of water and optimal amounts of salts and sialomucin (Oster and Yang, 1972).…”

Section: Resultsmentioning

confidence: 99%

Evaluation of Salivary Electrolytes during Normal Menstrual Cycle with Special Reference to Ovulation

Alagendran¹,

Archunan²,

Armando³

et al. 2010

American Journal of Applied Sciences

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Abstract:There is evidence to imply that estrogen influences salivary electrolytes activity in women. Problem statement: In this study we investigated changes in sodium, potassium and inorganic phosphorus, calcium and magnesium which related to find out the precise day of ovulation. These changes might help to explain the fluctuation of ovarian hormones such as preovulatory estrogen surge. Approach: Human whole saliva was collected from 48 healthy subjects of women (age range 20-30 years) during reproductive phases of menstrual cycle were assayed using atomic absorption spectrometer and enzyme immune assay. Amongst a range of electrolytes have been identified such as sodium, potassium, inorganic phosphorus and calcium were comparatively found to be higher during ovulatory phase when compared to that of other phases. Changes were attributed to a probable hormonal outcome on salivary composition. Results: Conversely, in other phases (preovulatory and postovulatory) electrolytes activity like magnesium and calcium decreased later, declining significantly (p<0.05). The increase of electrolytes like sodium and potassium in human saliva, during ovulatory phase might be due to the circulation of steroid hormones. Conclusion: Further, the presence of particular salts influence by ovarian hormones like LH and progesterone in ovulatory saliva makes the possibility to expand a sign for spotlight of ovulation by means of noninvasive method.

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Section: Resultsmentioning

confidence: 99%

Evaluation of Salivary Electrolytes during Normal Menstrual Cycle with Special Reference to Ovulation

Alagendran¹,

Archunan²,

Armando³

et al. 2010

American Journal of Applied Sciences

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“…Thus, it appears that sodium is lost in excess of water in the period of ovulation. It is known that saliva ferning depends principally on the electrolytes concentration (especially NaCl, KCl, CaCl 2 ) and chemo-physical properties of the mucins it contains (sialic acid) [16,17]. The estrogens increase the water content in mid-cycle and determine the most favorable condition, optimal proportion of water and optimal amounts of salts and sialomucin [18].…”

Section: Resultsmentioning

confidence: 99%

Evaluation of salivary electrolytes during estrous cycle in Murrah buffaloes with reference to estrus detection

et al. 2016

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Aim:Timely estrus detection is one of the critical factors for increasing reproductive efficiency in buffaloes. In recent decades, saliva has become a more popular as a noninvasive source for determining physiological status of animals by various biochemical electrolytes. This study was designed to assess and correlate changes in different salivary minerals concentration (calcium, inorganic phosphorus, magnesium, sodium, potassium, and chloride) during different stages of the estrous cycle in Murrah buffaloes.Materials and Methods:The saliva samples were collected during the different phases of the estrous cycle from 20 Murrah buffaloes in early morning hours and were assayed using respective minerals assay kits.Results:The concentrations of calcium (8.76±0.08-12.11±0.11 mg/dl), inorganic phosphorus (6.56±0.13-14.72±4.50 mg/dl), magnesium (2.27±0.14-5.79±0.15 mg/dl), sodium (139.47±0.31-159.62±1.22 mmol/L), potassium (12.40±0.22-26.85±1.22 mmol/L), and chloride (109.28±0.41-137.07±0.68 mmol/L) varied during the different phases of estrous cycle. The concentration of calcium, inorganic phosphorus, magnesium, sodium, potassium, and chloride in saliva were significantly (p<0.01) higher during estrus phase compared to other phases of the estrous cycle. All these minerals were positively and significantly (p<0.0001) related to estrogen concentration while salivary concentrations of calcium, magnesium, sodium, and chloride showed a significant (p<0.0001) negative correlation with progesterone level in blood plasma.Conclusion:These preliminary findings indicate that there are definite variations in salivary mineral and electrolyte concentrations during different phases of the estrous cycle. These results may be used as an aid for estrus detection/confirmation in buffaloes although validation of the results using a large number of animals is required.

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“…[ 18 ] using UV Spectrophotometry in human saliva by Alagendran et al . [ 19 ] In our study, saliva has been studied as a possible adjunct or as an alternative to estimation of serum LDH levels.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Serum and Salivary Lactate Dehydrogenase Levels in Patients with Oral Potentially Malignant Conditions/Lesions: A Clinical and Biochemical Study

Rao,

Babu,

Shetty

et al. 2024

Indian Journal of Community Medicine

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Background: Oral cancer encompasses all malignancies that originate in the oral tissues and remains a major public health problem throughout the world as an important case of poor health and illness. Head and neck cancer accounts for 9.8% of the estimated 6,44,600 incidental cancer cases in India. Oral Squamous Cell Carcinoma (SCC) is a serious and developing concern globally, accounting for more than 90% of malignant cancers of the oral cavity. Salivary diagnostics have been demonstrated to have potential in the detection and screening of oral pre-cancer and cancer in a variety of research settings. The continual and close contact between saliva and the mucosa, where cancer develops, is the foundation of this diagnostic capability. Materials and Methods: This research utilized spectrophotometry to quantify Lactate Dehydrogenase levels in serum and saliva of 30 healthy people which consisted the control group and 31 Oral Potentially Malignant people which constituted the study group. Results: On estimation and comparison, the mean Lactate Dehydrogenase levels in serum (397.4968+71.6392 IU/L) and saliva (675.4935+139.3352 IU/L) among patients with Oral Potentially malignant lesions/conditions were higher than the mean Lactate Dehydrogenase levels in serum (390.8667+71.0953 IU/L) and saliva (201.3700+89.1439 IU/L) among controls. Conclusion: Higher serum and salivary LDH levels in Oral Potentially malignant lesions/conditions than in control groups signifies the importance of assessing salivary LDH levels, in the prognosis of the same. Further prospective longitudinal studies are required to assess the salivary LDH levels among the patients with malignant transformation of Oral Potentially malignant lesions/conditions to oral cancers.

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Detection of Fatty Acids Profile in Human Saliva with Special Reference to Ovulation

Cited by 4 publications

References 26 publications

Evaluation of Salivary Electrolytes during Normal Menstrual Cycle with Special Reference to Ovulation

Evaluation of Salivary Electrolytes during Normal Menstrual Cycle with Special Reference to Ovulation

Evaluation of salivary electrolytes during estrous cycle in Murrah buffaloes with reference to estrus detection

Evaluation of Serum and Salivary Lactate Dehydrogenase Levels in Patients with Oral Potentially Malignant Conditions/Lesions: A Clinical and Biochemical Study

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