2020
DOI: 10.1590/1678-4324-2020190179
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Detection of Drug Resistant Mycobacterium Tuberculosis Strains Using Kit SIRE Nitratase®: a Multicenter Study

Abstract: (1) Background: The Commercial Kit SIRE Nitratase ® PlastLabor, is a drug susceptibility test kit used to detect Mycobacterium tuberculosis resistance to first-line TB treatment drugs. The present study aimed at evaluating its performance in a multicenter study. (2) Methods: To determine its accuracy, the proportion methods in Lowenstein Jensen medium or the BACTEC TM MGIT TM 960 system was used as a gold standard. (3) Results: The study revealed that the respective accuracies of the kit with 190 M. tuberculos… Show more

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“…Latent TB infection (LTBI) affects around 1.7 billion people, of which 5-15% will suffer from reactivation of TB during their lifetime [1,2]. Rapid and accurate diagnosis is crucial to reduce transmission and enhance primary treatment of infection, and the use of tools able to detect LTBI is of extreme importance for TB eradication [3].…”
Section: Introductionmentioning
confidence: 99%
“…Latent TB infection (LTBI) affects around 1.7 billion people, of which 5-15% will suffer from reactivation of TB during their lifetime [1,2]. Rapid and accurate diagnosis is crucial to reduce transmission and enhance primary treatment of infection, and the use of tools able to detect LTBI is of extreme importance for TB eradication [3].…”
Section: Introductionmentioning
confidence: 99%