Detection of antibiotic resistant enterococci and Escherichia coli in free range Iberian Lynx (Lynx pardinus)

Gonçalves, Alexandre; Igrejas, Gilberto; Radhouani, Hajer; Santos, Tiago; Monteiro, Ricardo; Pacheco, Ricardo; Alcaide, Eva; Zorrilla, Irene; Serra, Rodrigo; Torres, Carmén

doi:10.1016/j.scitotenv.2013.03.073

Cited by 36 publications

(42 citation statements)

References 38 publications

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“…Among 36 chloramphenicol-and florfenicol-resistant E. coli isolates from dogs suffering from urinary tract infections in Taiwan, all isolates harbored the cmlA gene and 18 carried the floR gene (196). The cmlA gene was also detected in two chloramphenicol-resistant E. coli isolates from fecal samples of free-range Iberian lynx (143). Of 89 E. coli isolates from giant pandas, 28 and 23 were resistant to chloramphenicol and florfenicol, respectively.…”

Section: Resistance To Phenicolsmentioning

confidence: 99%

“…ANT(2″) and ANT(3″) are encoded by the genes aadB and aadA, respectively (131), which are both frequently located on gene cassettes in class 1 integrons. These genes have also spread globally, and they have been found in E. coli from animals including pets, wild animals, and food-producing animals (134,(141)(142)(143)(144)(145)(146)(147)(148).…”

Section: Resistance To Aminoglycosides By Enzymatic Inactivationmentioning

confidence: 99%

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Antimicrobial Resistance inEscherichia coli

et al. 2018

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Multidrug resistance in has become a worrying issue that is increasingly observed in human but also in veterinary medicine worldwide. is intrinsically susceptible to almost all clinically relevant antimicrobial agents, but this bacterial species has a great capacity to accumulate resistance genes, mostly through horizontal gene transfer. The most problematic mechanisms in correspond to the acquisition of genes coding for extended-spectrum β-lactamases (conferring resistance to broad-spectrum cephalosporins), carbapenemases (conferring resistance to carbapenems), 16S rRNA methylases (conferring pan-resistance to aminoglycosides), plasmid-mediated quinolone resistance (PMQR) genes (conferring resistance to [fluoro]quinolones), and genes (conferring resistance to polymyxins). Although the spread of carbapenemase genes has been mainly recognized in the human sector but poorly recognized in animals, colistin resistance in seems rather to be related to the use of colistin in veterinary medicine on a global scale. For the other resistance traits, their cross-transfer between the human and animal sectors still remains controversial even though genomic investigations indicate that extended-spectrum β-lactamase producers encountered in animals are distinct from those affecting humans. In addition, of animal origin often also show resistances to other-mostly older-antimicrobial agents, including tetracyclines, phenicols, sulfonamides, trimethoprim, and fosfomycin. Plasmids, especially multiresistance plasmids, but also other mobile genetic elements, such as transposons and gene cassettes in class 1 and class 2 integrons, seem to play a major role in the dissemination of resistance genes. Of note, coselection and persistence of resistances to critically important antimicrobial agents in human medicine also occurs through the massive use of antimicrobial agents in veterinary medicine, such as tetracyclines or sulfonamides, as long as all those determinants are located on the same genetic elements.

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Section: Resistance To Phenicolsmentioning

confidence: 99%

Section: Resistance To Aminoglycosides By Enzymatic Inactivationmentioning

confidence: 99%

Antimicrobial Resistance inEscherichia coli

et al. 2018

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“…hirae has been described in marine sediment by several authors (Anderson et al, 2005;Byappanahalli et al, 2012), suggesting that it is a common finding in this environment. Moreover, several antibiotic resistance genes have been reported in E. hirae isolates from farm (Liu et al, 2012), domestic (Gosh et al, 2012) and wild (Gonçalves et al, 2013) animals, and in water for human consumption (Macedo et al, 2011). Erythromycin-and copper-resistant enterococci and the linkage between erm(B) and tcrB genes (Hasman and Aarestrup, 2002) have already been identified in E. faecium and E. faecalis strains from pigs (Fard et al, 2011) and in bovine milk (Kim et al, 2012).…”

mentioning

confidence: 99%

Erythromycin- and copper-resistant Enterococcus hirae from marine sediment and co-transfer of erm(B) and tcrB to human Enterococcus faecalis

Pasquaroli

Cesare

Vignaroli

et al. 2014

Diagnostic Microbiology and Infectious Disease

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“…Fourteen different tet genes encoding for efflux proteins have been studied in Gram-negative bacteria from different animals and humans origins, being tetA and tetB reported to be more associated in tetracycline resistance [19]. The mechanism of tetracycline resistance through active efflux encoded by the tetA gene was detected in the tetracycline-resistant E. coli isolate and it was the most frequent gene reported among isolates of E. coli from wild Portuguese seagulls and Iberian lynx [16,20]. The presence of the aadA gene was shown in 26 of 33 streptomycinresistant E. coli isolates.…”

Section: Resistance Among E Colimentioning

confidence: 99%