Detection of AFP with an ultra-sensitive giant magnetoimpedance biosensor

Ultrasensitive Magnetic Field Sensors for Biomedical Applications

“…There are also tests for blood coagulation, measurement of forces or stresses in artificial bones and the mass evaluation of cell cultures. Typical sensors being used in lab-on-a-chip systems are GMR/TMR [213][214][215], search coils [26,216,217], GMI [24,218], and Hall effect [219] magnetometers while for bioengineering purposes the most commonly used magnetic sensors are based on magnetoelasticity [220]. A significant advantage of magnetoresistive sensors in these applications is that they are fabricated with the same overall technology used to produce silicon chips, so it is relatively easy to manufacture them as part of an integrated lab-on-a-chip system.…”

“…Detection of biomarkers can also be performed with magnetic field sensors based on the magnetoimpedance effect. Work on the detection of a-fetoprotein bioconjugates with a GMI magnetometer (with the 100 fg/mL limit of detection) is made by Zhu et al [24]. Two papers demonstrating state-of-the-art GMI sensors in integrated microfluidic platforms were recently published by Feng et al [233,234].…”

“…A list of the common and modern magnetic field sensors with the potential to be used for the detection of biomagnetic signals (magnetocardiography (MCG), magnetoencephalography (MEG), magnetomyography (MMG), magnetoneurography (MNG)) and for point-of-care devices[18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35].…”

Novel Giant Magnetoimpedance Magnetic Field Sensor

“…This allows for linear characteristics to be achieved in the range of −Hk (anisotropy field) and +Hk. Utilizing the GMI effect to construct GMI sensors has been noted [32][33][34][35][36][37], and are used as magnetic memories [34], automotive sensors [35], or biosensors [32,33]. In this paper, a GMI magnetic field sensor was proposed, based on the double-peak characteristics of joule-annealed amorphous ribbons and a novel two-step, microprocessor-based automatic compensation measurement procedure.…”

The Influence of AC Driving Current on Magnetoimpedance in [Ni80Fe20/Cu]x/Cu/[Ni80Fe20/Cu]6-x Multilayers

“…One of the magnetic sensors that have attracted the attention of researchers was magnetoimpedancebased sensor and has many applications such as biosensors (Kurlyandskaya et al, 2003), mineral detection (Wang et al, 2015), nanoparticle detection (Beato-López et al, 2017), etc. Researchers have continued to investigate magnetoimpedance sensors with various parameters such as; magnetic properties (Corte-Leon et al, 2021), sensitivity (Zhu et al, 2019), etc.…”