Detection limit including selectivity as a criterion for line selection in trace analysis using inductively coupled plasma-atomic emission spectrometry (ICP-AES)—a tutorial treatment of a fundamental problem of AES

Capillary‐channeled polymer (C‐CP) fibers for the rapid extraction of proteins from urine matrices prior to detection with MALDI‐MS

“…With the optimized procedure, LODs were assessed to determine whether or not the PP C‐CP fiber μ‐SPE tips would indeed be relevant for extraction of low mass quantities in human urine. The single‐point LODs were determined by use of the “SBR‐RSD” method originally described by Boumans and Vrakking . In this approach, the LOD is defined as: where RSD is the RSD of the adjacent spectral background, m is the concentration of the test element in the specimen, S/B is the SBR, and the k is a statistical factor equal to 3, which reflects a 99% confidence interval.…”

Improving the Analytical Performances of Inductively Coupled Plasma Optical Emission Spectrometry by Multivariate Analysis Techniques

“…The procedure does not require or assume information about the sample composition or the preparation of solutions for the suspected interferents and allow some figures of merit to be calculated, namely the structured background factor, the overall spectral interference and the true detection limit (detection limit including selectivity as a criterion, ref. 45), which can be used as criteria to accept or reject an analytical line. Finally, Wirsz and Blades 46 proposed a factor analysis approach to optimize the line selection.…”

Use of multiple emission lines and principal component regression for quantitative analysis in inductively coupled plasma atomic emission spectrometry with charge coupled device detection

“…There is also no direct measurement of the degree of spectral interference, given only the Z and Zsam data matrices. Measures of line selectivity, such as those described by Boumans and Vrakking, 25 Bauer et ~1 . ~~ and Lorber2' require that the matrix of partial sensitivities for the interfering spectral lines are known.…”