2001
DOI: 10.1053/jlts.2001.26063
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Detection and treatment of coronary artery disease in liver transplant candidates

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Cited by 85 publications
(72 citation statements)
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“…Gastroesophageal varices are present in approximately half of patients with cirrhosis and data suggests that they develop in about 8% of cirrhotic patients without varices per year [20]. This manifestation of cirrhosis is due to blood stasis in the portal veins, which induces markedly higher pressure within the portal veins, and subsequently results in extrahepatic portosystemic shunts and varices [21]. Also, secondary to the decline of hepatic synthetic function, alterations in vasoreactive substances contribute significantly to the pathophysiology of portal hypertension characterized by increased intrahepatic vascular resistance and hyperdynamic circulation [22].…”
Section: Discussionmentioning
confidence: 99%
“…Gastroesophageal varices are present in approximately half of patients with cirrhosis and data suggests that they develop in about 8% of cirrhotic patients without varices per year [20]. This manifestation of cirrhosis is due to blood stasis in the portal veins, which induces markedly higher pressure within the portal veins, and subsequently results in extrahepatic portosystemic shunts and varices [21]. Also, secondary to the decline of hepatic synthetic function, alterations in vasoreactive substances contribute significantly to the pathophysiology of portal hypertension characterized by increased intrahepatic vascular resistance and hyperdynamic circulation [22].…”
Section: Discussionmentioning
confidence: 99%
“…However, in this study, there was no significant difference in the prevalence of coronary disease in males or females with advanced liver failure. This fact may be attributable to higher estrogen levels found in cirrhotic patients 4 .…”
Section: Discussionmentioning
confidence: 94%
“…Transplantation is the established treatment for advanced liver disease and liver failure. Therefore, in the United States 4000 liver transplants are performed annually 4 .…”
Section: Introductionmentioning
confidence: 99%
“…em um grupo de 1045 pacientes cirróticos (8) . De acordo com outro estudo, a prevalência de DAC relacionada à hepatopatia avançada foi até maior do que na população em geral (9) . A partir da interpretação desses dados, levando-se em consideração o fato de haver estudos indicando que ocorre aumento na morbidade e mortalidade dos hepatopatas crônicos que apresentam DAC quando são submetidos a transplante de fígado, mesmo quando a doença é tratada antes da realização do transplante (10) , podemos entender porque identificar, acompanhar e assistir esses pacientes é extremamente importante para o sucesso do transplante hepático e para a melhoria da qualidade de vida do hepatopata.…”
Section: Introductionunclassified