Detection and Characterization of Intracardiac Thrombi on MR  Imaging

Barkhausen, Jörg; Hunold, Peter; Eggebrecht, Holger; Schüler, W.; Sabin, Georg; Erbel, Raimund; Debatin, Jörg F.

doi:10.2214/ajr.179.6.1791539

Cited by 174 publications

(97 citation statements)

References 25 publications

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“…Finally, MR imaging offers many more techniques for tissue differentiation that were not integrated in our study protocol to keep the overall acquisition time within certain limits. MR imaging techniques such as rest perfusion imaging or postcontrast T1w imaging with long inversion times are often used for thrombus discrimination (20), whereas semiquantitative techniques such as diffusion-weighted imaging and T1 and T2 mapping might further improve the diagnostic accuracy in the assessment of cardiac tumors.…”

Section: Discussionmentioning

confidence: 99%

Integrated ¹⁸F-FDG PET/MR Imaging in the Assessment of Cardiac Masses: A Pilot Study

et al. 2014

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The objective of the present study was to evaluate whether integrated 18 F-FDG PET/MR imaging could improve the diagnostic workup in patients with cardiac masses. Methods: Twenty patients were prospectively assessed using integrated cardiac 18 F-FDG PET/MR imaging: 16 patients with cardiac masses of unknown identity and 4 patients with cardiac sarcoma after surgical therapy. All scans were obtained on an integrated 3-T PET/MR device. The MR protocol consisted of half Fourier acquisition single-shot turbo spin-echo sequence, cine, and T2-weighted images as well as T1-weighted images before and after injection of gadobutrol. PET data were acquired simultaneously with the MR scan after injection of 199 ± 58 MBq of 18 F-FDG. Patients were prepared with a high-fat, lowcarbohydrate diet in a period of 24 h before the examination, and 50 IU/kg of unfractionated heparin were administered intravenously 15 min before 18 F-FDG injection. Results: Cardiac masses were diagnosed as follows: metastases, 3; direct tumor infiltration via pulmonary vein, 1; local relapse of primary sarcoma after surgery, 2; Burkitt lymphoma, 1; scar/patch tissue after surgery of primary sarcoma, 2; myxoma, 4; fibroelastoma, 1; caseous calcification of mitral annulus, 3; and thrombus, 3. The maximum standardized uptake value (SUV max ) in malignant lesions was significantly higher than in nonmalignant cases (13.2 ± 6.2 vs. 2.3 ± 1.2, P 5 0.0004). When a threshold of 5.2 or greater was used, SUV max was found to yield 100% sensitivity and 92% specificity for the differentiation between malignant and nonmalignant cases. T2-weighted hyperintensity and contrast enhancement both yielded 100% sensitivity but a weak specificity of 54% and 46%, respectively. Morphologic tumor features as assessed by cine MR imaging yielded 86% sensitivity and 92% specificity. Consent interpretation using all available MR features yielded 100% sensitivity and 92% specificity. A Boolean 'AND' combination of an SUV max of 5.2 or greater with consent MR image interpretation improved sensitivity and specificity to 100%. Conclusion: In selected patients, 18 F-FDG PET/MR imaging can improve the noninvasive diagnosis and follow-up of cardiac masses.

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Section: Discussionmentioning

confidence: 99%

Integrated ¹⁸F-FDG PET/MR Imaging in the Assessment of Cardiac Masses: A Pilot Study

et al. 2014

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“…The strength of 2DE lies in its low cost and real-time visualisation of thrombus. Although MRI can detect intracardiac thrombi with sensitivity close to that of TEE [16], its high cost is often prohibitive and expertise is often lacking. Detection of atrial lesions on CT has also been described [17][18][19].…”

Section: Discussionmentioning

confidence: 99%

Multidetector row CT diagnosis of an infected right atrial thrombus following repeated dialysis catheter placement

Tan

Pua²,

Chia³

2009

BJR

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ABSTRACT. Right atrial thrombus formation is a known complication of dialysis catheter placements. We describe the case of a 61-year-old woman with end-stage renal failure who presented with gram-negative septicaemia. A gas-containing filling defect was noted incidentally in the right atrium during a CT scan of the abdomen and pelvis, indicative of a thrombus infected by a gas-forming organism. The finding correlated with a positive blood culture of Klebsiella pneumoniae and the twodimensional echocardiography finding of an echogenic atrial thrombus.

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“…Além disso, em massas ventriculares, a RMC também permite a diferenciação de tumores com trombos cavitários com melhor sensibilidade que o ecocardiograma 51 . No caso de trombos atriais, o ecocardiograma é o exame de escolha, pois a RMC tem sensibilidade menor nestes casos, sobretudo na avaliação do apêndice atrial.…”

Section: Tumores E Trombosunclassified

I Diretriz de Ressonância e Tomografia Cardiovascular da Sociedade Brasileira de Cardiologia Sumário Executivo

C¹,

Jasinowodolinsk²,

Lucchesi³

et al. 2006

Arq. Bras. Cardiol.

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Detection and Characterization of Intracardiac Thrombi on MR Imaging

Cited by 174 publications

References 25 publications

Integrated ¹⁸F-FDG PET/MR Imaging in the Assessment of Cardiac Masses: A Pilot Study

Integrated ¹⁸F-FDG PET/MR Imaging in the Assessment of Cardiac Masses: A Pilot Study

Multidetector row CT diagnosis of an infected right atrial thrombus following repeated dialysis catheter placement

I Diretriz de Ressonância e Tomografia Cardiovascular da Sociedade Brasileira de Cardiologia Sumário Executivo

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Detection and Characterization of Intracardiac Thrombi on MR Imaging

Cited by 174 publications

References 25 publications

Integrated 18F-FDG PET/MR Imaging in the Assessment of Cardiac Masses: A Pilot Study

Integrated 18F-FDG PET/MR Imaging in the Assessment of Cardiac Masses: A Pilot Study

Multidetector row CT diagnosis of an infected right atrial thrombus following repeated dialysis catheter placement

I Diretriz de Ressonância e Tomografia Cardiovascular da Sociedade Brasileira de Cardiologia Sumário Executivo

Contact Info

Product

Resources

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Integrated ¹⁸F-FDG PET/MR Imaging in the Assessment of Cardiac Masses: A Pilot Study

Integrated ¹⁸F-FDG PET/MR Imaging in the Assessment of Cardiac Masses: A Pilot Study