Detailed Analysis of Specific Nail Psoriasis Features and Their Correlations with Clinical Parameters: A Cross-Sectional Study

Kyriakou, Aikaterini; Patsatsi, Aikaterini; Sotiriadis, Dimitrios

doi:10.1159/000332974

Cited by 36 publications

(41 citation statements)

References 39 publications

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“…25, 81–83 Nail psoriasis can be quite painful and result in decreased functional ability and quality of life. 84 The prevalence of nail disease among patients with PsA ranges from 41–93%.…”

Section: Methodsmentioning

confidence: 99%

“…The prevalence of nail disease in PsO is around 15–50%. 23, 81, 83, 85–88 Nail disease (pitting and onycholysis in particular) have been associated with inflammation at the enthesis where the extensor tendon connects to the nail unit 89 and is often correlated with DIP joint involvement. 90, 91 Furthermore, thickening of the entheses of the extensor tendon on ultrasound was more common in patients with clinical nail changes.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

The Epidemiology of Psoriatic Arthritis

Ogdie

Weiss

2015

Rheumatic Disease Clinics of North America

398

256

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

The Epidemiology of Psoriatic Arthritis

Ogdie

Weiss

2015

Rheumatic Disease Clinics of North America

398

256

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“…It has been suggested that the normal nail is anchored to the skeleton via a network of entheses [11]. Patients with nail disease also have more subclinical enthesitis both at the distal interphalangeal joint level as well as at remote sites [12,13], although the link between the different patterns of nail disease and subclinical enthesitis remains enigmatic [14,15]. …”

Section: Introductionmentioning

confidence: 99%

Potential Use of Optical Coherence Tomography and High-Frequency Ultrasound for the Assessment of Nail Disease in Psoriasis and Psoriatic Arthritis

et al. 2013

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Background: Psoriatic nail disease is increasingly recognised to be of major clinical and research relevance. Clinical assessment remains the current gold standard for its evaluation. Objective: We compared optical coherence tomography (OCT) and ultrasound (US) for nail disease assessment in psoriatic disease. Methods: 18 patients with at least one involved nail and 12 healthy controls were scanned using OCT; psoriatic patients also had an US scan (using a linear probe at 9-14 MHz). Nail and contour abnormalities were documented. Clinical onychopathy was scored independently using the modified Nail Psoriasis Severity Index. Results: Among 180 nails, 67.8% had clinical findings whereas 33.9% were abnormal by US and 44.4% had abnormalities on OCT. A positive OCT had a sensitivity and specificity of 44.4 and 95.8%, respectively, with a positive likelihood ratio of 10.7 for nail disease. OCT demonstrated 76.3% absolute agreement compared with clinical assessment and 65% with US. OCT detected subtle abnormalities in 12 clinically normal nails and in 41 nails with normal US findings. Conclusion: These findings show that OCT has a potential for the systematic characterisation of psoriatic nail changes and could be useful in diagnosis and more objective assessment of treatment response.

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“…Bu oran literatür ile uyumluydu (1,2,14). En sık görülen tırnak tutulumu pitting, en az görülen ise splinter hemoraji olarak saptandı.…”

Section: Gereç Ve Yöntemunclassified

Tırnak Tutulumu Olan ve Olmayan Psoriazis Hastalarında Tırnak Yatağı ve Tırnak Plağı Kalınlığının Sonografik Olarak Değerlendirilmesi

Rifaioğlu¹,

Üstün²,

Şen³

et al. 2016

Kocatepe Tıp Dergisi

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ÖZAmaç: Psoriazis toplumda %1-3 sıklıkta görülen deri, eklemler ve tırnakları, tutan eritemli skuamlı inflamatuar bir hastalıktır. Psoriazis hastalarında tırnak tutulumu sıklığı %15-% 69 arasında değişmektedir. Ankilozan spondilit ise psoriatik artrit gibi seronegatif spondilartritlerdendir. Ultrasonografi günümüzde yumuşak dokuları değerlendirmek için yaygın kullanılan non invaziv bir görüntüleme yöntemidir.Bu çalışmada tırnak tutulumu olan ve olmayan psoriazis hastalarında tırnak yatak ve tırnak plak kalınlıklarını ultrasonografik olarak ölçerek ankilozan spondilit hastaları ve kontrol grubu ile karşılaştırmayı hedefledik. Gereç ve Yöntem:Otuzyedi psoriazis, 39 ankilozan spondilit hastası ile 33 sağlıklı kontrol çalışmaya dahil edildi. Psoriazis hastaları ile ankilozan spondilit ve kontrol grubunun "tırnak plak kalınlığı" ve "tırnak yatak kalınlığı" hasta oturur pozisyonda ve sağ el masa üzerinde nötral pozisyonda iken gri skala ultrasonografi (LOGIQ5Pre, GE, 4-11-MHz lineer prob) ile aynı hekim tarafından sağ el ikinci parmak tırnağında(indeks tırnak) ölçüldü. Bulgular: Tırnak yatak kalınlıkları psoriazis, ankilozan spondilit ve kontrol grubunda sırasıyla 1.60,1.58,1.51 mm olarak ölçüldü. Tırnak plak kalınlıkları ise psoriazis, ankilozan spondilit ve kontrol grubunda sırasıyla 0.64,0.62,0.68 mm olarak ölçüldü. Psoriazis grubu ile ankilozan spondilit ve kontrol grupları arasında tırnak yatak ve tırnak plak kalınlıkları açısından istatistiksel olarak fark yoktu.(p=0.13,p=0.45)Tırnak yatak kalınlığı, sağ el ikinci parmak tırnağı tutulumu olan hastalarda, olmayanlara göre istatistiksel olarak daha yüksek ölçüldü. (p=0.030) Sonuç: Sonuç olarak çalışmamızda tırnak plak ve tırnak yatak kalınlıkları ultrasonografik olarak değerlendirildiğinde psoriazis grubu ile kontrol grubu ve ankilozan spondilit hastaları arasında fark bulunmadı. Ultrasonografik olarak ölçülen tırnak yatak kalınlıkları sağ el ikinci parmak tırnağı tutulumu olan hastalarda, olmayanlara göre istatistiksel olarak daha yüksekti.Anahtar Kelimeler: Psoriazis; tırnak; ultrasonografi ABSTRACT Objective: Psoriasis is an inflammatory and erythematousscaly disease which involve the skin, joint and nail. It's prevalence is 1-3%. The incidence of nail involvement in psoriasis patient ranged between 15-69 %. Ultrasonography is a noninvasive imaging method widely using for assess the soft tissue image nowadays. In this study we aimed to assess the nail bed and nail plate thickness in psoriasis patient with and without nail involvement and compare with ankylosing spondylitis and control groups. Material and Methods:Thirty-seven patient with psoriasis, 39 patient with ankylosing spondylitis and 33 healthy control were included to the study. Nail bad and nail plate thicknesses was measured with grey scale USG(LOGIQ5Pre, GE, 4-11-MHz lineer prob) from the right hand's second finger(index finger), when the patient seated with the hands in a neutral position over the table.Results: Nail bad thicknesses were measured as 1.60, 1.58, 1.51 mm respectively in psoriasis, an...

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Detailed Analysis of Specific Nail Psoriasis Features and Their Correlations with Clinical Parameters: A Cross-Sectional Study

Cited by 36 publications

References 39 publications

The Epidemiology of Psoriatic Arthritis

The Epidemiology of Psoriatic Arthritis

Potential Use of Optical Coherence Tomography and High-Frequency Ultrasound for the Assessment of Nail Disease in Psoriasis and Psoriatic Arthritis

Tırnak Tutulumu Olan ve Olmayan Psoriazis Hastalarında Tırnak Yatağı ve Tırnak Plağı Kalınlığının Sonografik Olarak Değerlendirilmesi

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