The Epidemiology of Psoriatic Arthritis

Psoriasis and comorbid diseases

“…124 The prevalence of inflammatory arthritis in psoriasis patients ranges between 6–42% depending on the definitions used and populations studied. 125–138 The prevalence of PsA increases with greater psoriasis severity 125,133,139 and duration, 125,140 however, the severity of skin disease is only weakly associated with severity of joint disease.…”

“…125–138 The prevalence of PsA increases with greater psoriasis severity 125,133,139 and duration, 125,140 however, the severity of skin disease is only weakly associated with severity of joint disease. PsA has been associated with the distribution of psoriasis involvement (i.e., scalp, intergluteal, perianal) 141 and the presence of nail dystrophy, which is suggested to indicate early enthesial inflammation 124,141,142 .…”

“…The differential diagnosis includes osteoarthritis, RA, crystal arthropathy (e.g., gout or calcium pyrophosphate disease), and fibromyalgia. 124,143–147 . Undiagnosed PsA among psoriasis patients seen in the dermatology setting is prevalent and estimated at 15.5%.…”

Risk of uveitis and inflammatory bowel disease in people with psoriatic arthritis: a population-based cohort study

“…Psoriatic arthritis (PsA) is a chronic inflammatory arthritis which has been reported to affect between 10% and 40% of individuals with psoriasis 1. In the majority of patients, PsA presents after, or synchronously with, the onset of psoriasis.…”

Comparative Effectiveness of Adalimumab versus Secukinumab for the Treatment of Psoriatic Arthritis: A Matching-Adjusted Indirect Comparison

“…The prevalence of PsA is 0.3-1.0% in the general population and around 10-40% of psoriasis patients will develop PsA in their lifetime [1][2][3][4][5]. Disease severity varies amongst individuals and can range from mild swelling and inflammation to joint incapacitation.…”