Destruction of porous spherical Mo132 nanocluster polyoxometallate of keplerate type in aqueous solutions

Остроушко, А. А.; Tonkushina, M. O.

doi:10.1134/s0036024416020229

Cited by 19 publications

(19 citation statements)

References 26 publications

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“…Looking for additional applications of POM–dye associates, bioinspired technologies are also promising. Owing to the pH‐dependent destruction of giant POMs in aqueous media, these nanoclusters can reversibly bind the 10–20‐fold molecular excess of cationic dye without loss of colloidal stability and deactivate their fluorescence signal. Administrated into some living tissues through injection or iontophoresis, such associates will gradually release the dye molecules during POM destruction at physiological pH (7.2–7.4).…”

Section: Resultsmentioning

confidence: 99%

Fundamental Aspects of Xanthene Dye Aggregation on the Surfaces of Nanocluster Polyoxometalates: H‐ to J‐Aggregate Switching

Fazylova

Shevtsev

Михайлов

et al. 2020

Chemistry A European J

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The induced aggregation of the xanthenedye rho-damineB (RhB) on metal oxide centers belonging to the highly symmetric surfaces of precise nanoscale templates with Keplerate (Mo 132 )o rtoroidal (Mo 138 )s tructures has been studied. With the joint use of the Langmuir isotherma nd full Stern-Volmer models, the thermodynamic reasons for dye adsorption on the nanocluster surface, such as amixture of monomer,H -aggregate (H-dimer), and J-aggregate forms (which can coexist or switch one into another under the exact conditions), were established:t his was shown through UV/Vis and fluorescence spectroscopies. By using the frame-work of the excitonm odel, it is shownt hat the angle( a)b etweent he transition dipole moments of RhB is very sensitive to surface strain inside the dye sub-monolayer.A saresult, it is possible to switch from H-to J-aggregates by the postfunctionalization of polyoxometalate (POM)-RhB associates by the surfactant bilayer shell, which allows the surface strain to grow.R ecommendations are provided for managing the appearance of H-or J-aggregates on metal oxide (or polyelectrolyte) surfacesd uring photovoltaico rb ioimaging applications.[a] V. Fazylova, N. Shevtsev,S .M ikhailov, Prof. [b] G. Kim Institute of Organic Synthesis Ural Branch of the Russian Academyo fSciences 22 AkademicheskayaS t.,6 20990 Ekaterinburg (Russia) Supporting information and the ORCID identification number(s) for the author(s) of this article can be found under: https://doi.

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Section: Resultsmentioning

confidence: 99%

Fundamental Aspects of Xanthene Dye Aggregation on the Surfaces of Nanocluster Polyoxometalates: H‐ to J‐Aggregate Switching

Fazylova

Shevtsev

Михайлов

et al. 2020

Chemistry A European J

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“…The competitive interaction of drug cations with the existing complexing anions also complicates the formation of the cation-POM complexes [197]. On the other hand, there is a way to obtain transportable associates of anionic bioactive substances with POM, for example, through the bridging calcium cations [119,198]. The discovered POM stabilization in associates with calcium will be discussed below.…”

Section: Association Of Poms With Bioactive Substances and Polymersmentioning

confidence: 99%

“…The thiamine-POM ratio in the associates was estimated as 4:1, with the retention of the total negative charge of the conjugate. Mo 72 Fe 30 associates with substances belonging to the class of immunomodulators, e.g., with 2-morpholino-5-phenyl-6H-1,3,4-thiadiazine bromide [197][198][199][200][201][202].…”

Section: Association Of Poms With Bioactive Substances and Polymersmentioning

confidence: 99%

“…At the same time, it was shown that a thorough spectroscopic analysis and a comprehensive interpretation of the results are necessary [280,286] in order to avoid unreliable conclusions [284] about the POMs' thermal stability. The features of the processes of POMs destruction in solutions have been considered in the earlier performed works [135,198]. For each of the considered POM, there is a region of stable state in aqueous solutions in terms of POM concentration and medium pH.…”

Section: Poms Desrtuction Process and Their Stabilizationmentioning

confidence: 99%

“…The destruction of Mo 132 has also been investigated [198]. An analysis of the spectrophotometric data from experiments on the destruction of Mo 132 POM showed that the time dependencies of the optical density and, accordingly, of the POM concentration, have an induction period when the concentration decreases rather slowly.…”

Section: Poms Desrtuction Process and Their Stabilizationmentioning

confidence: 99%

See 2 more Smart Citations

Physicochemical and biochemical properties of the Keplerate-type nanocluster polyoxomolybdates as promising components for biomedical use

Ostroushko¹,

Grzhegorzhevskii²,

Medvedeva³

et al. 2021

Nanosystems: Phys. Chem. Math.

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The paper discusses the results of a research on physicochemical and biochemical properties of the Keplerate-type molybdenum-based nanocluster polyoxometalates (POMs), which show promise in the field of biomedicine as a means of targeted drug delivery, including the transport to immune privileged organs. POMs can be considered as components of releasing systems, including the long-acting ones with feedback (for controlling the drug active component release rate). POMs are promising drugs for the treatment of anemia. Also, the paper deals with the results of studies of POM effect on living systems at the molecular and cellular levels, at that of individual organs, and on the organism as a whole. The mechanism and kinetics of POM destruction and possibilities of stabilization, the oscillatory phenomena manifestation, the formation of POM conjugates with bioactive substances which can be released during the destruction of POM, with polymer components, and with indicator fluorescent dyes, as well as forecasts for further research, are considered.

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Association of Spherical Porous Nanocluster Keplerate-Type Polyoxometalate Mo72Fe30 with Biologically Active Substances

et al. 2017

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Destruction of porous spherical Mo132 nanocluster polyoxometallate of keplerate type in aqueous solutions

Cited by 19 publications

References 26 publications

Fundamental Aspects of Xanthene Dye Aggregation on the Surfaces of Nanocluster Polyoxometalates: H‐ to J‐Aggregate Switching

Fundamental Aspects of Xanthene Dye Aggregation on the Surfaces of Nanocluster Polyoxometalates: H‐ to J‐Aggregate Switching

Physicochemical and biochemical properties of the Keplerate-type nanocluster polyoxomolybdates as promising components for biomedical use

Association of Spherical Porous Nanocluster Keplerate-Type Polyoxometalate Mo72Fe30 with Biologically Active Substances

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