Values such as historical and cultural heritage and natural beauties belonging to a destination are very important in terms of identity creation and marketing of destinations. The attractiveness of these values, which are in the tourism sector, which is developing with a rapidly increasing momentum today, makes great contributions to the destinations. In addition, effective destination marketing provides an economic contribution to the region. In this context, Turkey, which is an important touristic destination with its rich tourism diversity, has important cultural routes. In the study, cultural routes in Turkey are examined in terms of political, economic, social and technological possibilities with PEST Analysis. According to the results of the evaluation, it has been determined that Turkey has a great potential in terms of cultural routes where millions of visitors walk every year in the world, but sufficient steps have not been taken in terms of tourism and destination marketing. In addition, it was concluded that the routes could not be protected due to the inadequacy of legal regulations and cooperation projects could not be made between the regions, and various suggestions were presented in this direction.