Designing highly crystalline multifunctional multicolor-luminescence nanosystem for tracking breast cancer heterogeneity

Abstract

Fruit based nanosystem can identify triple negative breast cancer cells.

Bio-Conjugated Magnetic-Fluorescence Nanoarchitectures for the Capture and Identification of Lung-Tumor-Derived Programmed Cell Death Lighand 1-Positive Exosomes

“…Figure 2 F shows the XPS data for the YFCDs, which clearly indicate the presence of a C 1s peak at 284.8 eV, an O 1s peak at 532.5 eV, and a N 1s peak at 398.1 eV. 30 − 33 On the basis of the XPS and EDX data, we can conclude that YFCDs contains both carboxy and amine groups in the surface, as shown in Figure 1 A.…”

“…The second broad peak is visible around λ max = 570 nm of the emission, which is mainly due to the surface −OH, −NH, —C=O functional groups and other groups bonded to the cores of the YFCDs. 30 − 33 We observed only one emission peak when the YFCDs were excited at 480 nm, as shown in Figure 3 E. The observed broad peak is around 570 nm, showing that the broad luminescence spectrum remains unchanged for YFCDs even when the the excitation wavelength is varied from 300 to 480 nm. To measure the photoluminescence quantum yield (PLQY), we used quinine sulfate as a standard (QY = 54%).…”

“… 30 − 32 On the other hand, the second lower-energy absorption peak, which is mainly due to the n → π* transitions in C–O bonds originating from the surface functional groups attached to the carbon backbone of YFCDs, was observed at 436 nm. 30 − 33 Panels B and C in Figure 3 show photographs of the YFCDs in the presence and absence of 380 nm UV light, respectively. The photograph shown in Figure 3 C clearly shows the emission of strong yellow fluorescence from the YFCDs in the presence of 380 nm UV light.…”

“…To measure the photoluminescence quantum yield (PLQY), we used quinine sulfate as a standard (QY = 54%). 20 , 31 − 33 By measuring the fluorescence intensity from a standard and the YFCDs, we determined the PLQY for YFCDS is 0.31 at an excitation wavelength of 480 nm. Figure 3 F shows the time-dependent photoluminescence decay profiles for YFCDs at an excitation wavelength of 480 nm.…”

“…As shown in Figure 1 B, we used a coprecipitation method with ferric chloride and 1,6-hexanedioic acid for this purpose. 31 − 33 The experimental details are reported in the Supporting Information . After the reaction between ferric chloride and 1,6-hexanedioic acid was complete, the black precipitate was separated using a neodymium magnet.…”