Designing a dual-function skin-stretching device with 3D printing for mechanotransduction analysis and scar prevention: A preliminary study

Wu, Xiaoyi; Chen, Heng; Luo, Tianhao; Wang, Zhuo; Wei, Zequan; Li, Lin; Yang, Xuewen; Sa, Guodong; Sa, Guoliang

doi:10.1016/j.matdes.2022.110862

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Therapeutics Based On Mechanical Regulation1

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2024

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“…Western blot showed that the mechanical sensitive molecule YAP was related to the mechanical force applied on the skin. 131 Table 2. Materials for regulating wound mechanical forces.…”

Section: Therapeutics Based On Mechanical Regulationmentioning

confidence: 99%

New insights into balancing wound healing and scarless skin repair

Zhou

Xie

et al. 2023

J Tissue Eng

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Scars caused by skin injuries after burns, wounds, abrasions and operations have serious physical and psychological effects on patients. In recent years, the research of scar free wound repair has been greatly expanded. However, understanding the complex mechanisms of wound healing, in which various cells, cytokines and mechanical force interact, is critical to developing a treatment that can achieve scarless wound healing. Therefore, this paper reviews the types of wounds, the mechanism of scar formation in the healing process, and the current research progress on the dual consideration of wound healing and scar prevention, and some strategies for the treatment of scar free wound repair.

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“…Western blot showed that the mechanical sensitive molecule YAP was related to the mechanical force applied on the skin. 131 Table 2. Materials for regulating wound mechanical forces.…”

Section: Therapeutics Based On Mechanical Regulationmentioning

confidence: 99%