Design, Synthesis, and Characterization of Nucleic-Acid-Functionalized Gold Surfaces for Biomarker Detection

Adams, Nicholas M.; Jackson, Stephen R.; Haselton, Frederick R.; Wright, David W.

doi:10.1021/la2028862

Cited by 41 publications

(26 citation statements)

References 80 publications

(252 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Immobilization of aptamers on the electrode surface is highly important. Several immobilization techniques, such as thiolation, diazonium coupling, and click chemistry, are reported [73][74][75]. Among all, diazotization coupling provides better immobilization impact due to the lack of leakage of bio-recognition elements on storage.…”

Section: Aptamer-based Sensing Strategies For Aflatoxins (Afs) Detectionmentioning

confidence: 99%

Recent Advances in Electrochemical-Based Sensing Platforms for Aflatoxins Detection

et al. 2016

View full text Add to dashboard Cite

Abstract:Mycotoxin are small (MW~700 Da), toxic secondary metabolites produced by fungal species that readily colonize crops and contaminate them at both pre-and post-harvesting. Among all, aflatoxins (AFs) are mycotoxins of major significance due to their presence in common food commodities and the potential threat to human health worldwide. Based on the severity of illness and increased incidences of AFs poisoning, a broad range of conventional and analytical detection techniques that could be useful and practical have already been reported. However, due to the variety of structural analogous of these toxins, it is impossible to use one common technique for their analysis. Numerous recent research efforts have been directed to explore alternative detection technologies. Recently, immunosensors and aptasensors have gained promising potential in the area of sample preparation and detection systems. These sensors offer the advantages of disposability, portability, miniaturization, and on-site analysis. In a typical design of an aptasensor, an aptamer (ssDNA or RNA) is used as a bio-recognition element either integrated within or in intimate association with the transducer surface. This review paper is focused on the recent advances in electrochemical immunoand aptasensing platforms for detection of AFs in real samples.

show abstract

Section: Aptamer-based Sensing Strategies For Aflatoxins (Afs) Detectionmentioning

confidence: 99%

Recent Advances in Electrochemical-Based Sensing Platforms for Aflatoxins Detection

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Then, nanoparticles are released on the chip. Many highperformance systems are based on this principle and differ mainly in their transduction mode (Campolongo et al 2010;Pei et al 2013;Adams et al 2012). While the magnetic nanoparticle is always used, the detection nanoparticle nature is adapted to the transduction mode.…”

Section: Enzyme-assisted Dna-labelled Antibody Amplificationmentioning

confidence: 99%

DNA for Non-nucleic Acid Sensing

2015

View full text Add to dashboard Cite

“…The advantages of high stability, superior biocompatibility, high surface energy, strong amplification effect on signals, etc., made them excellent choices for biosensor applications. [6][7][8][9][10][11][12][13][14][15][16][17][18] For this review, literature search was conducted in PubMed, Web of Science, as well as Google Scholar. Various types of sensors for biological detections are discussed in this review.…”

Section: Introductionmentioning

confidence: 99%

Nanomaterial-based biosensors for biological detections

Su¹,

Li²,

Jin³

et al. 2017

AHCT

View full text Add to dashboard Cite

Nanomaterial-based biosensors have become one of the major topics in the field of diagnostics. With the growing demand on devices with improved sensitivity and selectivity, rapid response time, and low cost, four categories of nanomaterials have become popular in biosensor research: gold nanoparticles, graphene, carbon nanotubes, and photonic crystals. The ongoing research has brought new designs of biosensors based on nanomaterials, which have greatly improved the potential of field-deployable microfabricated devices. This review describes the recent technologies employing the aforementioned nanomaterials for electrochemical detection of biomolecules, including glucose, DNA, protein, toxins, and so on. We envisage that miniaturized lab-on-a-chip devices employing these nanomaterials will soon be an essential part of our daily life.

show abstract

Design, Synthesis, and Characterization of Nucleic-Acid-Functionalized Gold Surfaces for Biomarker Detection

Cited by 41 publications

References 80 publications

Recent Advances in Electrochemical-Based Sensing Platforms for Aflatoxins Detection

Recent Advances in Electrochemical-Based Sensing Platforms for Aflatoxins Detection

DNA for Non-nucleic Acid Sensing

Nanomaterial-based biosensors for biological detections

Contact Info

Product

Resources

About